BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 22472693)

  • 41. Pharmacophore Modeling, virtual and in vitro screening for acetylcholinesterase inhibitors and their effects on amyloid-β self- assembly.
    Bag S; Tulsan R; Sood A; Datta S; Török M
    Curr Comput Aided Drug Des; 2013 Mar; 9(1):2-14. PubMed ID: 22734711
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonism.
    Lange JH; Coolen HK; van der Neut MA; Borst AJ; Stork B; Verveer PC; Kruse CG
    J Med Chem; 2010 Feb; 53(3):1338-46. PubMed ID: 20047331
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Synthesis, biological evaluation and molecular modeling of aloe-emodin derivatives as new acetylcholinesterase inhibitors.
    Shi DH; Huang W; Li C; Wang LT; Wang SF
    Bioorg Med Chem; 2013 Mar; 21(5):1064-73. PubMed ID: 23380475
    [TBL] [Abstract][Full Text] [Related]  

  • 44. On the value of homology models for virtual screening: discovering hCXCR3 antagonists by pharmacophore-based and structure-based approaches.
    Huang D; Gu Q; Ge H; Ye J; Salam NK; Hagler A; Chen H; Xu J
    J Chem Inf Model; 2012 May; 52(5):1356-66. PubMed ID: 22545675
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
    Camps P; Formosa X; Galdeano C; Muñoz-Torrero D; Ramírez L; Gómez E; Isambert N; Lavilla R; Badia A; Clos MV; Bartolini M; Mancini F; Andrisano V; Arce MP; Rodríguez-Franco MI; Huertas O; Dafni T; Luque FJ
    J Med Chem; 2009 Sep; 52(17):5365-79. PubMed ID: 19663388
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.
    Alonso D; Dorronsoro I; Rubio L; Muñoz P; García-Palomero E; Del Monte M; Bidon-Chanal A; Orozco M; Luque FJ; Castro A; Medina M; Martínez A
    Bioorg Med Chem; 2005 Dec; 13(24):6588-97. PubMed ID: 16230018
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors.
    Pisani L; Catto M; Giangreco I; Leonetti F; Nicolotti O; Stefanachi A; Cellamare S; Carotti A
    ChemMedChem; 2010 Sep; 5(9):1616-30. PubMed ID: 20677317
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819).
    Bartolucci C; Siotto M; Ghidini E; Amari G; Bolzoni PT; Racchi M; Villetti G; Delcanale M; Lamba D
    J Med Chem; 2006 Aug; 49(17):5051-8. PubMed ID: 16913695
    [TBL] [Abstract][Full Text] [Related]  

  • 49. In silico Structure-based Identification of Novel Acetylcholinesterase Inhibitors Against Alzheimer's Disease.
    Iman K; Mirza MU; Mazhar N; Vanmeert M; Irshad I; Kamal MA
    CNS Neurol Disord Drug Targets; 2018 Apr; 17(1):54-68. PubMed ID: 29336270
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Novel tacrine-melatonin hybrids as dual-acting drugs for Alzheimer disease, with improved acetylcholinesterase inhibitory and antioxidant properties.
    Rodríguez-Franco MI; Fernández-Bachiller MI; Pérez C; Hernández-Ledesma B; Bartolomé B
    J Med Chem; 2006 Jan; 49(2):459-62. PubMed ID: 16420031
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Use of ligand-based pharmacophore modeling and docking approach to find novel acetylcholinesterase inhibitors for treating Alzheimer's.
    Dhanjal JK; Sharma S; Grover A; Das A
    Biomed Pharmacother; 2015 Apr; 71():146-52. PubMed ID: 25960230
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Structure-Based Discovery of Dual-Target Hits for Acetylcholinesterase and the α7 Nicotinic Acetylcholine Receptors: In Silico Studies and In Vitro Confirmation.
    Oddsson S; Kowal NM; Ahring PK; Olafsdottir ES; Balle T
    Molecules; 2020 Jun; 25(12):. PubMed ID: 32580406
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Virtual screening of acetylcholinesterase inhibitors using the Lipinski's rule of five and ZINC databank.
    Nogara PA; Saraiva Rde A; Caeran Bueno D; Lissner LJ; Lenz Dalla Corte C; Braga MM; Rosemberg DB; Rocha JB
    Biomed Res Int; 2015; 2015():870389. PubMed ID: 25685814
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Substituted spiro [2.3'] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase.
    Ali MA; Ismail R; Choon TS; Yoon YK; Wei AC; Pandian S; Kumar RS; Osman H; Manogaran E
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7064-6. PubMed ID: 20951037
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis and biological evaluation of tacrine-thiadiazolidinone hybrids as dual acetylcholinesterase inhibitors.
    Dorronsoro I; Alonso D; Castro A; del Monte M; García-Palomero E; Martínez A
    Arch Pharm (Weinheim); 2005 Jan; 338(1):18-23. PubMed ID: 15674800
    [TBL] [Abstract][Full Text] [Related]  

  • 56. A combinatorial feature selection approach to describe the QSAR of dual site inhibitors of acetylcholinesterase.
    Asadabadi EB; Abdolmaleki P; Barkooie SM; Jahandideh S; Rezaei MA
    Comput Biol Med; 2009 Dec; 39(12):1089-95. PubMed ID: 19854437
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Novel non-peptide beta-secretase inhibitors derived from structure-based virtual screening and bioassay.
    Xu W; Chen G; Liew OW; Zuo Z; Jiang H; Zhu W
    Bioorg Med Chem Lett; 2009 Jun; 19(12):3188-92. PubMed ID: 19447035
    [TBL] [Abstract][Full Text] [Related]  

  • 58. The discovery of potential acetylcholinesterase inhibitors: a combination of pharmacophore modeling, virtual screening, and molecular docking studies.
    Lu SH; Wu JW; Liu HL; Zhao JH; Liu KT; Chuang CK; Lin HY; Tsai WB; Ho Y
    J Biomed Sci; 2011 Jan; 18(1):8. PubMed ID: 21251245
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.
    Camps P; El Achab R; Görbig DM; Morral J; Muñoz-Torrero D; Badia A; Eladi Baños J; Vivas NM; Barril X; Orozco M; Luque FJ
    J Med Chem; 1999 Aug; 42(17):3227-42. PubMed ID: 10464010
    [TBL] [Abstract][Full Text] [Related]  

  • 60. AChE inhibitor: a regio- and stereo-selective 1,3-dipolar cycloaddition for the synthesis of novel substituted 5,6-dimethoxy spiro[5.3']-oxindole-spiro-[6.3″]-2,3-dihydro-1H-inden-1″-one-7-(substituted aryl)-tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole.
    Ashraf Ali M; Ismail R; Choon TS; Kumar RS; Osman H; Arumugam N; Almansour AI; Elumalai K; Singh A
    Bioorg Med Chem Lett; 2012 Jan; 22(1):508-11. PubMed ID: 22142546
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.