BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 22472693)

  • 61. Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation.
    Bolognesi ML; Andrisano V; Bartolini M; Banzi R; Melchiorre C
    J Med Chem; 2005 Jan; 48(1):24-7. PubMed ID: 15633997
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Structure-based pharmacophore design and virtual screening for novel angiotensin converting enzyme 2 inhibitors.
    Rella M; Rushworth CA; Guy JL; Turner AJ; Langer T; Jackson RM
    J Chem Inf Model; 2006; 46(2):708-16. PubMed ID: 16563001
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Shao D; Zou C; Luo C; Tang X; Li Y
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4639-42. PubMed ID: 15324879
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Molecular modelling and enzymatic studies of acetylcholinesterase and butyrylcholinesterase recognition with paraquat and related compounds.
    Alcaro S; Arcone R; Vecchio I; Ortuso F; Gallelli A; Pasceri R; Procopio A; Iannone M
    SAR QSAR Environ Res; 2007; 18(5-6):595-602. PubMed ID: 17654339
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Discovery of huperzine A-tacrine hybrids as potent inhibitors of human cholinesterases targeting their midgorge recognition sites.
    Gemma S; Gabellieri E; Huleatt P; Fattorusso C; Borriello M; Catalanotti B; Butini S; De Angelis M; Novellino E; Nacci V; Belinskaya T; Saxena A; Campiani G
    J Med Chem; 2006 Jun; 49(11):3421-5. PubMed ID: 16722663
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Blood-brain barrier permeable anticholinesterase aurones: synthesis, structure-activity relationship, and drug-like properties.
    Liew KF; Chan KL; Lee CY
    Eur J Med Chem; 2015 Apr; 94():195-210. PubMed ID: 25768702
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Acetylcholinesterase capillary enzyme reactor for screening and characterization of selective inhibitors.
    da Silva JI; de Moraes MC; Vieira LC; Corrêa AG; Cass QB; Cardoso CL
    J Pharm Biomed Anal; 2013 Jan; 73():44-52. PubMed ID: 22391555
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Designing Second Generation Anti-Alzheimer Compounds as Inhibitors of Human Acetylcholinesterase: Computational Screening of Synthetic Molecules and Dietary Phytochemicals.
    Amat-Ur-Rasool H; Ahmed M
    PLoS One; 2015; 10(9):e0136509. PubMed ID: 26325402
    [TBL] [Abstract][Full Text] [Related]  

  • 70. The discovery of novel β-secretase inhibitors: pharmacophore modeling, virtual screening, and docking studies.
    Niu Y; Ma C; Jin H; Xu F; Gao H; Liu P; Li Y; Wang C; Yang G; Xu P
    Chem Biol Drug Des; 2012 Jun; 79(6):972-80. PubMed ID: 22381116
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Lead identification of acetylcholinesterase inhibitors-histamine H3 receptor antagonists from molecular modeling.
    Bembenek SD; Keith JM; Letavic MA; Apodaca R; Barbier AJ; Dvorak L; Aluisio L; Miller KL; Lovenberg TW; Carruthers NI
    Bioorg Med Chem; 2008 Mar; 16(6):2968-73. PubMed ID: 18249544
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease.
    Marco-Contelles J; León R; de Los Ríos C; Guglietta A; Terencio J; López MG; García AG; Villarroya M
    J Med Chem; 2006 Dec; 49(26):7607-10. PubMed ID: 17181144
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Synthesis and acetylcholinesterase and butyrylcholinesterase inhibitory activities of 7-alkoxyl substituted indolizinoquinoline-5,12-dione derivatives.
    Wu ZP; Wu XW; Shen T; Li YP; Cheng X; Gu LQ; Huang ZS; An LK
    Arch Pharm (Weinheim); 2012 Mar; 345(3):175-84. PubMed ID: 21989769
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Molecular evaluation of herbal compounds as potent inhibitors of acetylcholinesterase for the treatment of Alzheimer's disease.
    Chen YX; Li GZ; Zhang B; Xia ZY; Zhang M
    Mol Med Rep; 2016 Jul; 14(1):446-52. PubMed ID: 27176468
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors--analogues of SAD-128.
    Musilek K; Roder J; Komloova M; Holas O; Hrabinova M; Pohanka M; Dohnal V; Opletalova V; Kuca K; Jung YS
    Bioorg Med Chem Lett; 2011 Jan; 21(1):150-4. PubMed ID: 21144749
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimer's disease.
    Szymański P; Janik A; Zurek E; Mikiciuk-Olasik E
    Pharmazie; 2011 Jun; 66(6):399-403. PubMed ID: 21699076
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Pharmacophore-based drug design for potential AChE inhibitors from Traditional Chinese Medicine Database.
    Jiang Y; Gao H
    Bioorg Chem; 2018 Feb; 76():400-414. PubMed ID: 29258018
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Identification of novel acetylcholinesterase inhibitors through e-pharmacophore-based virtual screening and molecular dynamics simulations.
    Malik R; Choudhary BS; Srivastava S; Mehta P; Sharma M
    J Biomol Struct Dyn; 2017 Nov; 35(15):3268-3284. PubMed ID: 27782777
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Design, synthesis, and evaluation of 2-phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors.
    Sheng R; Lin X; Li J; Jiang Y; Shang Z; Hu Y
    Bioorg Med Chem Lett; 2005 Sep; 15(17):3834-7. PubMed ID: 15993600
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Catechol alkenyls from Semecarpus anacardium: acetylcholinesterase inhibition and binding mode predictions.
    Adhami HR; Linder T; Kaehlig H; Schuster D; Zehl M; Krenn L
    J Ethnopharmacol; 2012 Jan; 139(1):142-8. PubMed ID: 22075454
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.