291 related articles for article (PubMed ID: 22473810)
1. Probing of C-terminal lysine variation in a recombinant monoclonal antibody production using Chinese hamster ovary cells with chemically defined media.
Luo J; Zhang J; Ren D; Tsai WL; Li F; Amanullah A; Hudson T
Biotechnol Bioeng; 2012 Sep; 109(9):2306-15. PubMed ID: 22473810
[TBL] [Abstract][Full Text] [Related]
2. Culture temperature modulates monoclonal antibody charge variation distribution in Chinese hamster ovary cell cultures.
Zhang X; Sun YT; Tang H; Fan L; Hu D; Liu J; Liu X; Tan WS
Biotechnol Lett; 2015 Nov; 37(11):2151-7. PubMed ID: 26149578
[TBL] [Abstract][Full Text] [Related]
3. C-terminal lysine variants in fully human monoclonal antibodies: investigation of test methods and possible causes.
Dick LW; Qiu D; Mahon D; Adamo M; Cheng KC
Biotechnol Bioeng; 2008 Aug; 100(6):1132-43. PubMed ID: 18553400
[TBL] [Abstract][Full Text] [Related]
4. Carboxypeptidase D is the only enzyme responsible for antibody C-terminal lysine cleavage in Chinese hamster ovary (CHO) cells.
Hu Z; Zhang H; Haley B; Macchi F; Yang F; Misaghi S; Elich J; Yang R; Tang Y; Joly JC; Snedecor BR; Shen A
Biotechnol Bioeng; 2016 Oct; 113(10):2100-6. PubMed ID: 26989081
[TBL] [Abstract][Full Text] [Related]
5. Bcl-x(L) mediates increased production of humanized monoclonal antibodies in Chinese hamster ovary cells.
Chiang GG; Sisk WP
Biotechnol Bioeng; 2005 Sep; 91(7):779-92. PubMed ID: 15986489
[TBL] [Abstract][Full Text] [Related]
6. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.
Dorai H; Corisdeo S; Ellis D; Kinney C; Chomo M; Hawley-Nelson P; Moore G; Betenbaugh MJ; Ganguly S
Biotechnol Bioeng; 2012 Apr; 109(4):1016-30. PubMed ID: 22068683
[TBL] [Abstract][Full Text] [Related]
7. Development of a fed-batch culture process for enhanced production of recombinant human antithrombin by Chinese hamster ovary cells.
Kuwae S; Ohda T; Tamashima H; Miki H; Kobayashi K
J Biosci Bioeng; 2005 Nov; 100(5):502-10. PubMed ID: 16384788
[TBL] [Abstract][Full Text] [Related]
8. Impact of cell culture process changes on endogenous retrovirus expression.
Brorson K; De Wit C; Hamilton E; Mustafa M; Swann PG; Kiss R; Taticek R; Polastri G; Stein KE; Xu Y
Biotechnol Bioeng; 2002 Nov; 80(3):257-67. PubMed ID: 12226857
[TBL] [Abstract][Full Text] [Related]
9. A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells.
Legmann R; Schreyer HB; Combs RG; McCormick EL; Russo AP; Rodgers ST
Biotechnol Bioeng; 2009 Dec; 104(6):1107-20. PubMed ID: 19623562
[TBL] [Abstract][Full Text] [Related]
10. Elucidating the effects of arginine and lysine on a monoclonal antibody C-terminal lysine variation in CHO cell cultures.
Zhang X; Tang H; Sun YT; Liu X; Tan WS; Fan L
Appl Microbiol Biotechnol; 2015 Aug; 99(16):6643-52. PubMed ID: 25947244
[TBL] [Abstract][Full Text] [Related]
11. Increase in efficiency of media utilization for recombinant protein production in Chinese hamster ovary culture through dilution.
Thombre S; Gadgil M
Biotechnol Appl Biochem; 2011; 58(1):25-31. PubMed ID: 21446956
[TBL] [Abstract][Full Text] [Related]
12. Chemometrics and in-line near infrared spectroscopic monitoring of a biopharmaceutical Chinese hamster ovary cell culture: prediction of multiple cultivation variables.
Clavaud M; Roggo Y; Von Daeniken R; Liebler A; Schwabe JO
Talanta; 2013 Jul; 111():28-38. PubMed ID: 23622522
[TBL] [Abstract][Full Text] [Related]
13. A single nutrient feed supports both chemically defined NS0 and CHO fed-batch processes: Improved productivity and lactate metabolism.
Ma N; Ellet J; Okediadi C; Hermes P; McCormick E; Casnocha S
Biotechnol Prog; 2009; 25(5):1353-63. PubMed ID: 19637321
[TBL] [Abstract][Full Text] [Related]
14. Effects of cell culture conditions on antibody N-linked glycosylation--what affects high mannose 5 glycoform.
Pacis E; Yu M; Autsen J; Bayer R; Li F
Biotechnol Bioeng; 2011 Oct; 108(10):2348-58. PubMed ID: 21557201
[TBL] [Abstract][Full Text] [Related]
15. Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed.
Chaderjian WB; Chin ET; Harris RJ; Etcheverry TM
Biotechnol Prog; 2005; 21(2):550-3. PubMed ID: 15801797
[TBL] [Abstract][Full Text] [Related]
16. Control of culture environment for improved polyethylenimine-mediated transient production of recombinant monoclonal antibodies by CHO cells.
Galbraith DJ; Tait AS; Racher AJ; Birch JR; James DC
Biotechnol Prog; 2006; 22(3):753-62. PubMed ID: 16739959
[TBL] [Abstract][Full Text] [Related]
17. Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed-batch culture.
Chong WP; Goh LT; Reddy SG; Yusufi FN; Lee DY; Wong NS; Heng CK; Yap MG; Ho YS
Rapid Commun Mass Spectrom; 2009 Dec; 23(23):3763-71. PubMed ID: 19902412
[TBL] [Abstract][Full Text] [Related]
18. Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment.
Huang YM; Hu W; Rustandi E; Chang K; Yusuf-Makagiansar H; Ryll T
Biotechnol Prog; 2010; 26(5):1400-10. PubMed ID: 20945494
[TBL] [Abstract][Full Text] [Related]
19. Amino acid and glucose metabolism in fed-batch CHO cell culture affects antibody production and glycosylation.
Fan Y; Jimenez Del Val I; Müller C; Wagtberg Sen J; Rasmussen SK; Kontoravdi C; Weilguny D; Andersen MR
Biotechnol Bioeng; 2015 Mar; 112(3):521-35. PubMed ID: 25220616
[TBL] [Abstract][Full Text] [Related]
20. Defining process design space for monoclonal antibody cell culture.
Abu-Absi SF; Yang L; Thompson P; Jiang C; Kandula S; Schilling B; Shukla AA
Biotechnol Bioeng; 2010 Aug; 106(6):894-905. PubMed ID: 20589669
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
