These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Characterization of Cysteinylation and Trisulfide Bonds in a Recombinant Monoclonal Antibody. Kita A; Ponniah G; Nowak C; Liu H Anal Chem; 2016 May; 88(10):5430-7. PubMed ID: 27115984 [TBL] [Abstract][Full Text] [Related]
5. Evidence for trisulfide bonds in a recombinant variant of a human IgG2 monoclonal antibody. Pristatsky P; Cohen SL; Krantz D; Acevedo J; Ionescu R; Vlasak J Anal Chem; 2009 Aug; 81(15):6148-55. PubMed ID: 19591437 [TBL] [Abstract][Full Text] [Related]
6. Identification and prevention of antibody disulfide bond reduction during cell culture manufacturing. Trexler-Schmidt M; Sargis S; Chiu J; Sze-Khoo S; Mun M; Kao YH; Laird MW Biotechnol Bioeng; 2010 Jun; 106(3):452-61. PubMed ID: 20178122 [TBL] [Abstract][Full Text] [Related]
7. A predictive high-throughput scale-down model of monoclonal antibody production in CHO cells. Legmann R; Schreyer HB; Combs RG; McCormick EL; Russo AP; Rodgers ST Biotechnol Bioeng; 2009 Dec; 104(6):1107-20. PubMed ID: 19623562 [TBL] [Abstract][Full Text] [Related]
8. Step-up/step-down perfusion approach for increased mAb 520C9 production by a hybridoma cell line. Sen S; Roychoudhury PK Biotechnol Lett; 2013 Feb; 35(2):153-63. PubMed ID: 23086570 [TBL] [Abstract][Full Text] [Related]
9. Trisulfide modification impacts the reduction step in antibody-drug conjugation process. Cumnock K; Tully T; Cornell C; Hutchinson M; Gorrell J; Skidmore K; Chen Y; Jacobson F Bioconjug Chem; 2013 Jul; 24(7):1154-60. PubMed ID: 23713462 [TBL] [Abstract][Full Text] [Related]
10. Culture temperature modulates aggregation of recombinant antibody in cho cells. Gomez N; Subramanian J; Ouyang J; Nguyen MD; Hutchinson M; Sharma VK; Lin AA; Yuk IH Biotechnol Bioeng; 2012 Jan; 109(1):125-36. PubMed ID: 21965146 [TBL] [Abstract][Full Text] [Related]
11. An empirical modeling platform to evaluate the relative control discrete CHO cell synthetic processes exert over recombinant monoclonal antibody production process titer. McLeod J; O'Callaghan PM; Pybus LP; Wilkinson SJ; Root T; Racher AJ; James DC Biotechnol Bioeng; 2011 Sep; 108(9):2193-204. PubMed ID: 21445882 [TBL] [Abstract][Full Text] [Related]
12. Characterization of a novel modification to monoclonal antibodies: thioether cross-link of heavy and light chains. Tous GI; Wei Z; Feng J; Bilbulian S; Bowen S; Smith J; Strouse R; McGeehan P; Casas-Finet J; Schenerman MA Anal Chem; 2005 May; 77(9):2675-82. PubMed ID: 15859580 [TBL] [Abstract][Full Text] [Related]
13. Impact of S-sulfocysteine on fragments and trisulfide bond linkages in monoclonal antibodies. Seibel R; Maier S; Schnellbaecher A; Bohl S; Wehsling M; Zeck A; Zimmer A MAbs; 2017; 9(6):889-897. PubMed ID: 28581887 [TBL] [Abstract][Full Text] [Related]
14. Effects of buffering conditions and culture pH on production rates and glycosylation of clinical phase I anti-melanoma mouse IgG3 monoclonal antibody R24. Müthing J; Kemminer SE; Conradt HS; Sagi D; Nimtz M; Kärst U; Peter-Katalinić J Biotechnol Bioeng; 2003 Aug; 83(3):321-34. PubMed ID: 12783488 [TBL] [Abstract][Full Text] [Related]
15. Metabolomics profiling of extracellular metabolites in recombinant Chinese Hamster Ovary fed-batch culture. Chong WP; Goh LT; Reddy SG; Yusufi FN; Lee DY; Wong NS; Heng CK; Yap MG; Ho YS Rapid Commun Mass Spectrom; 2009 Dec; 23(23):3763-71. PubMed ID: 19902412 [TBL] [Abstract][Full Text] [Related]
16. Development toward rapid and efficient screening for high performance hydrolysate lots in a recombinant monoclonal antibody manufacturing process. Luo Y; Pierce KM Biotechnol Prog; 2012 Jul; 28(4):1061-8. PubMed ID: 22641483 [TBL] [Abstract][Full Text] [Related]
17. Perfusion culture of hybridoma cells for hyperproduction of IgG(2a) monoclonal antibody in a wave bioreactor-perfusion culture system. Tang YJ; Ohashi R; Hamel JF Biotechnol Prog; 2007; 23(1):255-64. PubMed ID: 17269696 [TBL] [Abstract][Full Text] [Related]
18. Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule. Ouellette D; Alessandri L; Chin A; Grinnell C; Tarcsa E; Radziejewski C; Correia I Anal Biochem; 2010 Feb; 397(1):37-47. PubMed ID: 19766583 [TBL] [Abstract][Full Text] [Related]
19. A high-yielding, generic fed-batch cell culture process for production of recombinant antibodies. Sauer PW; Burky JE; Wesson MC; Sternard HD; Qu L Biotechnol Bioeng; 2000 Mar; 67(5):585-97. PubMed ID: 10649233 [TBL] [Abstract][Full Text] [Related]
20. On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells. Schlatter S; Stansfield SH; Dinnis DM; Racher AJ; Birch JR; James DC Biotechnol Prog; 2005; 21(1):122-33. PubMed ID: 15903249 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]