BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 22477152)

  • 1. Recent advances in the genetics of the ALS-FTLD complex.
    Morris HR; Waite AJ; Williams NM; Neal JW; Blake DJ
    Curr Neurol Neurosci Rep; 2012 Jun; 12(3):243-50. PubMed ID: 22477152
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum.
    Van Langenhove T; van der Zee J; Van Broeckhoven C
    Ann Med; 2012 Dec; 44(8):817-28. PubMed ID: 22420316
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.
    Gallagher MD; Suh E; Grossman M; Elman L; McCluskey L; Van Swieten JC; Al-Sarraj S; Neumann M; Gelpi E; Ghetti B; Rohrer JD; Halliday G; Van Broeckhoven C; Seilhean D; Shaw PJ; Frosch MP; Alafuzoff I; Antonell A; Bogdanovic N; Brooks W; Cairns NJ; Cooper-Knock J; Cotman C; Cras P; Cruts M; De Deyn PP; DeCarli C; Dobson-Stone C; Engelborghs S; Fox N; Galasko D; Gearing M; Gijselinck I; Grafman J; Hartikainen P; Hatanpaa KJ; Highley JR; Hodges J; Hulette C; Ince PG; Jin LW; Kirby J; Kofler J; Kril J; Kwok JB; Levey A; Lieberman A; Llado A; Martin JJ; Masliah E; McDermott CJ; McKee A; McLean C; Mead S; Miller CA; Miller J; Munoz DG; Murrell J; Paulson H; Piguet O; Rossor M; Sanchez-Valle R; Sano M; Schneider J; Silbert LC; Spina S; van der Zee J; Van Langenhove T; Warren J; Wharton SB; White CL; Woltjer RL; Trojanowski JQ; Lee VM; Van Deerlin V; Chen-Plotkin AS
    Acta Neuropathol; 2014 Mar; 127(3):407-18. PubMed ID: 24442578
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mixed tau, TDP-43 and p62 pathology in FTLD associated with a C9ORF72 repeat expansion and p.Ala239Thr MAPT (tau) variant.
    King A; Al-Sarraj S; Troakes C; Smith BN; Maekawa S; Iovino M; Spillantini MG; Shaw CE
    Acta Neuropathol; 2013 Feb; 125(2):303-10. PubMed ID: 23053136
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia.
    Lashley T; Rohrer JD; Mahoney C; Gordon E; Beck J; Mead S; Warren J; Rossor M; Revesz T
    Neuropathol Appl Neurobiol; 2014 Jun; 40(4):502-13. PubMed ID: 24286341
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine.
    Irwin DJ; Cairns NJ; Grossman M; McMillan CT; Lee EB; Van Deerlin VM; Lee VM; Trojanowski JQ
    Acta Neuropathol; 2015 Apr; 129(4):469-91. PubMed ID: 25549971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders.
    Janssens J; Van Broeckhoven C
    Hum Mol Genet; 2013 Oct; 22(R1):R77-87. PubMed ID: 23900071
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases.
    Bit-Ivan EN; Suh E; Shim HS; Weintraub S; Hyman BT; Arnold SE; McCarty-Wood E; Van Deerlin VM; Schneider JA; Trojanowski JQ; Frosch MP; Baker MC; Rademakers R; Mesulam M; Bigio EH
    J Neuropathol Exp Neurol; 2014 May; 73(5):467-73. PubMed ID: 24709683
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutation analysis of VCP in British familial and sporadic amyotrophic lateral sclerosis patients.
    Miller JW; Smith BN; Topp SD; Al-Chalabi A; Shaw CE; Vance C
    Neurobiol Aging; 2012 Nov; 33(11):2721.e1-2. PubMed ID: 22789697
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility.
    Gleixner AM; Verdone BM; Otte CG; Anderson EN; Ramesh N; Shapiro OR; Gale JR; Mauna JC; Mann JR; Copley KE; Daley EL; Ortega JA; Cicardi ME; Kiskinis E; Kofler J; Pandey UB; Trotti D; Donnelly CJ
    Nat Commun; 2022 Jun; 13(1):3380. PubMed ID: 35697676
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amyotrophic lateral sclerosis-frontotemporal lobar dementia in 3 families with p.Ala382Thr TARDBP mutations.
    Chiò A; Calvo A; Moglia C; Restagno G; Ossola I; Brunetti M; Montuschi A; Cistaro A; Ticca A; Traynor BJ; Schymick JC; Mutani R; Marrosu MG; Murru MR; Borghero G
    Arch Neurol; 2010 Aug; 67(8):1002-9. PubMed ID: 20697052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Screening for C9ORF72 repeat expansion in FTLD.
    Ferrari R; Mok K; Moreno JH; Cosentino S; Goldman J; Pietrini P; Mayeux R; Tierney MC; Kapogiannis D; Jicha GA; Murrell JR; Ghetti B; Wassermann EM; Grafman J; Hardy J; Huey ED; Momeni P
    Neurobiol Aging; 2012 Aug; 33(8):1850.e1-11. PubMed ID: 22459598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population.
    Beck J; Poulter M; Hensman D; Rohrer JD; Mahoney CJ; Adamson G; Campbell T; Uphill J; Borg A; Fratta P; Orrell RW; Malaspina A; Rowe J; Brown J; Hodges J; Sidle K; Polke JM; Houlden H; Schott JM; Fox NC; Rossor MN; Tabrizi SJ; Isaacs AM; Hardy J; Warren JD; Collinge J; Mead S
    Am J Hum Genet; 2013 Mar; 92(3):345-53. PubMed ID: 23434116
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion.
    Udine E; DeJesus-Hernandez M; Tian S; das Neves SP; Crook R; Finch NA; Baker MC; Pottier C; Graff-Radford NR; Boeve BF; Petersen RC; Knopman DS; Josephs KA; Oskarsson B; Da Mesquita S; Petrucelli L; Gendron TF; Dickson DW; Rademakers R; van Blitterswijk M
    Acta Neuropathol; 2024 Apr; 147(1):73. PubMed ID: 38641715
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity.
    Nicholson AM; Zhou X; Perkerson RB; Parsons TM; Chew J; Brooks M; DeJesus-Hernandez M; Finch NA; Matchett BJ; Kurti A; Jansen-West KR; Perkerson E; Daughrity L; Castanedes-Casey M; Rousseau L; Phillips V; Hu F; Gendron TF; Murray ME; Dickson DW; Fryer JD; Petrucelli L; Rademakers R
    Acta Neuropathol Commun; 2018 May; 6(1):42. PubMed ID: 29855382
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy.
    Gitcho MA; Bigio EH; Mishra M; Johnson N; Weintraub S; Mesulam M; Rademakers R; Chakraverty S; Cruchaga C; Morris JC; Goate AM; Cairns NJ
    Acta Neuropathol; 2009 Nov; 118(5):633-45. PubMed ID: 19618195
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
    Pottier C; Ren Y; Perkerson RB; Baker M; Jenkins GD; van Blitterswijk M; DeJesus-Hernandez M; van Rooij JGJ; Murray ME; Christopher E; McDonnell SK; Fogarty Z; Batzler A; Tian S; Vicente CT; Matchett B; Karydas AM; Hsiung GR; Seelaar H; Mol MO; Finger EC; Graff C; Öijerstedt L; Neumann M; Heutink P; Synofzik M; Wilke C; Prudlo J; Rizzu P; Simon-Sanchez J; Edbauer D; Roeber S; Diehl-Schmid J; Evers BM; King A; Mesulam MM; Weintraub S; Geula C; Bieniek KF; Petrucelli L; Ahern GL; Reiman EM; Woodruff BK; Caselli RJ; Huey ED; Farlow MR; Grafman J; Mead S; Grinberg LT; Spina S; Grossman M; Irwin DJ; Lee EB; Suh E; Snowden J; Mann D; Ertekin-Taner N; Uitti RJ; Wszolek ZK; Josephs KA; Parisi JE; Knopman DS; Petersen RC; Hodges JR; Piguet O; Geier EG; Yokoyama JS; Rissman RA; Rogaeva E; Keith J; Zinman L; Tartaglia MC; Cairns NJ; Cruchaga C; Ghetti B; Kofler J; Lopez OL; Beach TG; Arzberger T; Herms J; Honig LS; Vonsattel JP; Halliday GM; Kwok JB; White CL; Gearing M; Glass J; Rollinson S; Pickering-Brown S; Rohrer JD; Trojanowski JQ; Van Deerlin V; Bigio EH; Troakes C; Al-Sarraj S; Asmann Y; Miller BL; Graff-Radford NR; Boeve BF; Seeley WW; Mackenzie IRA; van Swieten JC; Dickson DW; Biernacka JM; Rademakers R
    Acta Neuropathol; 2019 Jun; 137(6):879-899. PubMed ID: 30739198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuronal VCP loss of function recapitulates FTLD-TDP pathology.
    Wani A; Zhu J; Ulrich JD; Eteleeb A; Sauerbeck AD; Reitz SJ; Arhzaouy K; Ikenaga C; Yuede CM; Pittman SK; Wang F; Li S; Benitez BA; Cruchaga C; Kummer TT; Harari O; Chou TF; Schröder R; Clemen CS; Weihl CC
    Cell Rep; 2021 Jul; 36(3):109399. PubMed ID: 34289347
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New genes, new dilemmas: FTLD genetics and its implications for families.
    Goldman JS; Adamson J; Karydas A; Miller BL; Hutton M
    Am J Alzheimers Dis Other Demen; 2007 Dec-2008 Jan; 22(6):507-15. PubMed ID: 18166610
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recent advances in the molecular genetics of frontotemporal lobar degeneration.
    Rainero I; Rubino E; Michelerio A; D'Agata F; Gentile S; Pinessi L
    Funct Neurol; 2017; 32(1):7-16. PubMed ID: 28380318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.