85 related articles for article (PubMed ID: 22483389)
1. Dimerization of β-tryptase inhibitors, does it work for both basic and neutral P1 groups?
Liang G; Choi-Sledeski YM; Chen X; Gong Y; MacMillan EW; Tsay J; Sides K; Cairns J; Kulitzscher B; Aldous DJ; Morize I; Pauls HW
Bioorg Med Chem Lett; 2012 May; 22(9):3370-6. PubMed ID: 22483389
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of human beta-tryptase by Bowman-Birk inhibitor derived peptides: creation of a new tri-functional inhibitor.
Scarpi D; McBride JD; Leatherbarrow RJ
Bioorg Med Chem; 2004 Dec; 12(23):6045-52. PubMed ID: 15519150
[TBL] [Abstract][Full Text] [Related]
3. Structure-guided design of peptide-based tryptase inhibitors.
McGrath ME; Sprengeler PA; Hirschbein B; Somoza JR; Lehoux I; Janc JW; Gjerstad E; Graupe M; Estiarte A; Venkataramani C; Liu Y; Yee R; Ho JD; Green MJ; Lee CS; Liu L; Tai V; Spencer J; Sperandio D; Katz BA
Biochemistry; 2006 May; 45(19):5964-73. PubMed ID: 16681368
[TBL] [Abstract][Full Text] [Related]
4. A new approach to inhibit human β-tryptase by protein surface binding of four-armed peptide ligands with two different sets of arms.
Jiang QQ; Bartsch L; Sicking W; Wich PR; Heider D; Hoffmann D; Schmuck C
Org Biomol Chem; 2013 Feb; 11(10):1631-9. PubMed ID: 23358683
[TBL] [Abstract][Full Text] [Related]
5. The arginine mimicking β-amino acid β³hPhe(3-H₂N-CH₂) as S1 ligand in cyclotheonamide-based β-tryptase inhibitors.
Janke D; Sommerhoff CP; Schaschke N
Bioorg Med Chem; 2011 Dec; 19(23):7236-43. PubMed ID: 22047802
[TBL] [Abstract][Full Text] [Related]
6. Formation of active monomers from tetrameric human beta-tryptase.
Fajardo I; Pejler G
Biochem J; 2003 Feb; 369(Pt 3):603-10. PubMed ID: 12387726
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and biological activity of a targeted library of potential tryptase inhibitors.
García M; del Rio X; Silvestre S; Rubiralta M; Lozoya E; Segarra V; Fernández D; Miralpeix M; Aparici M; Diez A
Org Biomol Chem; 2004 Jun; 2(11):1633-42. PubMed ID: 15162216
[TBL] [Abstract][Full Text] [Related]
8. A fluorescent light-up probe as an inhibitor of intracellular β-tryptase.
Wang Q; Shi X; Zhu X; Ehlers M; Wu J; Schmuck C
Chem Commun (Camb); 2014 Jun; 50(46):6120-2. PubMed ID: 24776645
[TBL] [Abstract][Full Text] [Related]
9. Reversible and noncompetitive inhibition of beta-tryptase by protein surface binding of tetravalent peptide ligands identified from a combinatorial split-mix library.
Wich PR; Schmuck C
Angew Chem Int Ed Engl; 2010 Jun; 49(24):4113-6. PubMed ID: 20432495
[No Abstract] [Full Text] [Related]
10. Mast cell tryptase beta as a target in allergic inflammation: an evolving story.
Sommerhoff CP; Schaschke N
Curr Pharm Des; 2007; 13(3):313-32. PubMed ID: 17313363
[TBL] [Abstract][Full Text] [Related]
11. Novel pyrazinone inhibitors of mast cell tryptase: synthesis and SAR evaluation.
Hopkins C; Neuenschwander K; Scotese A; Jackson S; Nieduzak T; Pauls H; Liang G; Sides K; Cramer D; Cairns J; Maignan S; Mathieu M
Bioorg Med Chem Lett; 2004 Oct; 14(19):4819-23. PubMed ID: 15341931
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and evaluation of 4-substituted benzylamine derivatives as beta-tryptase inhibitors.
Miyazaki Y; Kato Y; Manabe T; Shimada H; Mizuno M; Egusa T; Ohkouchi M; Shiromizu I; Matsusue T; Yamamoto I
Bioorg Med Chem Lett; 2006 Jun; 16(11):2986-90. PubMed ID: 16540315
[TBL] [Abstract][Full Text] [Related]
13. Designed calix[8]arene-based ligands for selective tryptase surface recognition.
Mecca T; Consoli GM; Geraci C; Cunsolo F
Bioorg Med Chem; 2004 Oct; 12(19):5057-62. PubMed ID: 15351389
[TBL] [Abstract][Full Text] [Related]
14. Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.
Sutton JC; Bolton SA; Davis ME; Hartl KS; Jacobson B; Mathur A; Ogletree ML; Slusarchyk WA; Zahler R; Seiler SM; Bisacchi GS
Bioorg Med Chem Lett; 2004 May; 14(9):2233-9. PubMed ID: 15081015
[TBL] [Abstract][Full Text] [Related]
15. Peptidyl beta-homo-aspartals (3-amino-4-carboxybutyraldehydes): new specific inhibitors of caspases.
Bajusz S; Fauszt I; Németh K; Barabás E; Juhász A; Patthy M; Bauer PI
Biopolymers; 1999; 51(1):109-18. PubMed ID: 10380358
[TBL] [Abstract][Full Text] [Related]
16. Human beta-tryptase: detection and characterization of the active monomer and prevention of tetramer reconstitution by protease inhibitors.
Fukuoka Y; Schwartz LB
Biochemistry; 2004 Aug; 43(33):10757-64. PubMed ID: 15311937
[TBL] [Abstract][Full Text] [Related]
17. Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase.
Giardina SF; Werner DS; Pingle M; Feinberg PB; Foreman KW; Bergstrom DE; Arnold LD; Barany F
J Med Chem; 2020 Mar; 63(6):3004-3027. PubMed ID: 32057241
[TBL] [Abstract][Full Text] [Related]
18. Efficient synthesis of an enantiopure beta-lactam as an advanced precursor of thrombin and tryptase inhibitors.
Annunziata R; Benaglia M; Cinquini M; Cozzi F; Maggioni F; Puglisi A
J Org Chem; 2003 Apr; 68(7):2952-5. PubMed ID: 12662075
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of human beta-tryptase by Bowman-Birk inhibitor derived peptides.
Scarpi D; McBride JD; Leatherbarrow RJ
J Pept Res; 2002 Feb; 59(2):90-3. PubMed ID: 11906611
[TBL] [Abstract][Full Text] [Related]
20. Novel thrombin inhibitors incorporating weakly basic heterobicyclic P1-arginine mimetics: optimization via modification of P1 and P3 moieties.
Kranjc A; Peterlin-Masic L; Ilas J; Prezelj A; Stegnar M; Kikelj D
Bioorg Med Chem Lett; 2004 Jun; 14(12):3251-6. PubMed ID: 15149685
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]