BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

385 related articles for article (PubMed ID: 22483397)

  • 1. High-sensitivity liquid chromatography-tandem mass spectrometry for the simultaneous determination of five drugs and their cytochrome P450-specific probe metabolites in human plasma.
    Oh KS; Park SJ; Shinde DD; Shin JG; Kim DH
    J Chromatogr B Analyt Technol Biomed Life Sci; 2012 May; 895-896():56-64. PubMed ID: 22483397
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats.
    Zhang S; Song N; Li Q; Fan H; Liu C
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Aug; 871(1):78-89. PubMed ID: 18614408
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapid determination of five probe drugs and their metabolites in human plasma and urine by liquid chromatography/tandem mass spectrometry: application to cytochrome P450 phenotyping studies.
    Yin OQ; Lam SS; Lo CM; Chow MS
    Rapid Commun Mass Spectrom; 2004; 18(23):2921-33. PubMed ID: 15529418
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simultaneous LC-MS/MS analysis of the plasma concentrations of a cocktail of 5 cytochrome P450 substrate drugs and their metabolites.
    Tanaka S; Uchida S; Inui N; Takeuchi K; Watanabe H; Namiki N
    Biol Pharm Bull; 2014; 37(1):18-25. PubMed ID: 24389476
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.
    Zhang W; Han F; Guo P; Zhao H; Lin ZJ; Huang MQ; Bertelsen K; Weng N
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(15-16):1169-77. PubMed ID: 20378422
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Highly sensitive LC-MS/MS methods for the determination of seven human CYP450 activities using small oral doses of probe-drugs in human.
    Grangeon A; Gravel S; Gaudette F; Turgeon J; Michaud V
    J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Jan; 1040():144-158. PubMed ID: 27978469
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A rapid and simple LC-MS/MS method for the simultaneous evaluation of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 hydroxylation capacity.
    de Andrés F; Sosa-Macías M; Llerena A
    Bioanalysis; 2014 Mar; 6(5):683-96. PubMed ID: 24620810
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LC-MS/MS analysis of the plasma concentrations of a cocktail of 5 cytochrome P450 and P-glycoprotein probe substrates and their metabolites using subtherapeutic doses.
    Cusinato DAC; Filgueira GCO; Rocha A; Cintra MACT; Lanchote VL; Coelho EB
    J Pharm Biomed Anal; 2019 Feb; 164():430-441. PubMed ID: 30445356
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probe drugs and their corresponding metabolites in human serum and urine.
    Puris E; Pasanen M; Gynther M; Häkkinen MR; Pihlajamäki J; Keränen T; Honkakoski P; Raunio H; Petsalo A
    Anal Bioanal Chem; 2017 Jan; 409(1):251-268. PubMed ID: 27734142
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simultaneous Determination of Five Cytochrome P450 Probe Substrates and Their Metabolites and Organic Anion Transporting Polypeptide Probe Substrate in Human Plasma Using Liquid Chromatography-Tandem Mass Spectrometry.
    Heo JK; Kim HJ; Lee GH; Ohk B; Lee S; Song KS; Song IS; Liu KH; Yoon YR
    Pharmaceutics; 2018 Jul; 10(3):. PubMed ID: 30004443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An improved cytochrome P450 phenotyping cocktail with a simplified and highly sensitive UHPLC-MS/MS assay in human plasma.
    Eagles SK; Wang X; Gross AS; McLachlan AJ
    J Chromatogr B Analyt Technol Biomed Life Sci; 2020 Mar; 1140():122013. PubMed ID: 32050158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma.
    Bosilkovska M; Déglon J; Samer C; Walder B; Desmeules J; Staub C; Daali Y
    Bioanalysis; 2014 Jan; 6(2):151-64. PubMed ID: 24423593
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous determination of bupropion, metroprolol, midazolam, phenacetin, omeprazole and tolbutamide in rat plasma by UPLC-MS/MS and its application to cytochrome P450 activity study in rats.
    Ma J; Wang S; Zhang M; Zhang Q; Zhou Y; Lin C; Lin G; Wang X
    Biomed Chromatogr; 2015 Aug; 29(8):1203-12. PubMed ID: 25582505
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of nine drugs and their cytochrome P450-specific probe metabolites from urine by liquid chromatography-tandem mass spectrometry utilizing sub 2 microm particle size column.
    Petsalo A; Turpeinen M; Pelkonen O; Tolonen A
    J Chromatogr A; 2008 Dec; 1215(1-2):107-15. PubMed ID: 19019380
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A UHPLC-MS/MS method coupled with liquid-liquid extraction for the quantitation of phenacetin, omeprazole, metoprolol, midazolam and their metabolites in rat plasma and its application to the study of four CYP450 activities.
    Wang Z; Sun W; Lin ZF; Sun R; Huang CK; Ye WJ; Dong YY; Zhang XD; Chen RJ
    J Pharm Biomed Anal; 2019 Jan; 163():204-210. PubMed ID: 30317077
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry.
    Qin CZ; Ren X; Tan ZR; Chen Y; Yin JY; Yu J; Qu J; Zhou HH; Liu ZQ
    Biomed Chromatogr; 2014 Feb; 28(2):197-203. PubMed ID: 23946123
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
    Liu LY; Han YL; Zhu JH; Yu Q; Yang QJ; Lu J; Guo C
    Biomed Chromatogr; 2015 Mar; 29(3):437-44. PubMed ID: 25098274
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and validation of a sensitive and specific LC-MS/MS cocktail assay for CYP450 enzymes: Application to study the effect of catechin on rat hepatic CYP activity.
    Nguyen V; Espiritu M; Elbarbry F
    Biomed Chromatogr; 2020 Mar; 34(3):e4789. PubMed ID: 31885091
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LC-MS/MS method for the simultaneous quantification of intestinal CYP and UGT activity.
    Busch D; Fritz A; Partecke LI; Heidecke CD; Oswald S
    J Pharm Biomed Anal; 2018 Jun; 155():194-201. PubMed ID: 29649788
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simultaneous determination of febuxostat and its three active metabolites in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study in Chinese healthy volunteers.
    Wu Y; Mao Z; Liu Y; Wang X; Di X
    J Pharm Biomed Anal; 2015 Oct; 114():216-21. PubMed ID: 26072013
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.