212 related articles for article (PubMed ID: 22483633)
1. On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
da Silva Júnior EN; de Melo IM; Diogo EB; Costa VA; de Souza Filho JD; Valença WO; Camara CA; de Oliveira RN; de Araujo AS; Emery FS; dos Santos MR; de Simone CA; Menna-Barreto RF; de Castro SL
Eur J Med Chem; 2012 Jun; 52():304-12. PubMed ID: 22483633
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
Diogo EB; Dias GG; Rodrigues BL; Guimarães TT; Valença WO; Camara CA; de Oliveira RN; da Silva MG; Ferreira VF; de Paiva YG; Goulart MO; Menna-Barreto RF; de Castro SL; da Silva Júnior EN
Bioorg Med Chem; 2013 Nov; 21(21):6337-48. PubMed ID: 24074878
[TBL] [Abstract][Full Text] [Related]
3. Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi.
da Silva EN; Menna-Barreto RF; Pinto Mdo C; Silva RS; Teixeira DV; de Souza MC; De Simone CA; De Castro SL; Ferreira VF; Pinto AV
Eur J Med Chem; 2008 Aug; 43(8):1774-80. PubMed ID: 18045742
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.
da Silva Júnior EN; de Souza MC; Fernandes MC; Menna-Barreto RF; Pinto Mdo C; de Assis Lopes F; de Simone CA; Andrade CK; Pinto AV; Ferreira VF; de Castro SL
Bioorg Med Chem; 2008 May; 16(9):5030-8. PubMed ID: 18378461
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological activity against Trypanosoma cruzi of substituted 1,4-naphthoquinones.
Olímpio da Silva A; da Silva Lopes R; Vieira de Lima R; Santos Suniga Tozatti C; Marques MR; de Albuquerque S; Beatriz A; Pires de Lima D
Eur J Med Chem; 2013 Feb; 60():51-6. PubMed ID: 23279867
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of naphthofuranquinones with activity against Trypanosoma cruzi.
Silva RS; Costa EM; Trindade UL; Teixeira DV; Pinto Mde C; Santos GL; Malta VR; De Simone CA; Pinto AV; de Castro SL
Eur J Med Chem; 2006 Apr; 41(4):526-30. PubMed ID: 16500733
[TBL] [Abstract][Full Text] [Related]
7. New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms.
Carneiro PF; do Nascimento SB; Pinto AV; Pinto Mdo C; Lechuga GC; Santos DO; dos Santos Júnior HM; Resende JA; Bourguignon SC; Ferreira VF
Bioorg Med Chem; 2012 Aug; 20(16):4995-5000. PubMed ID: 22795899
[TBL] [Abstract][Full Text] [Related]
8. Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
Salas C; Tapia RA; Ciudad K; Armstrong V; Orellana M; Kemmerling U; Ferreira J; Maya JD; Morello A
Bioorg Med Chem; 2008 Jan; 16(2):668-74. PubMed ID: 18029184
[TBL] [Abstract][Full Text] [Related]
9. Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound.
Lara LS; Moreira CS; Calvet CM; Lechuga GC; Souza RS; Bourguignon SC; Ferreira VF; Rocha D; Pereira MCS
Eur J Med Chem; 2018 Jan; 144():572-581. PubMed ID: 29289882
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and anti-Trypanosoma cruzi activity of new 3-phenylthio-nor-β-lapachone derivatives.
Cardoso MFDC; Salomão K; Bombaça AC; da Rocha DR; da Silva FC; Cavaleiro JAS; de Castro SL; Ferreira VF
Bioorg Med Chem; 2015 Aug; 23(15):4763-4768. PubMed ID: 26118339
[TBL] [Abstract][Full Text] [Related]
11. 1,2,3-Triazole-based analogue of benznidazole displays remarkable activity against Trypanosoma cruzi.
de Andrade P; Galo OA; Carvalho MR; Lopes CD; Carneiro ZA; Sesti-Costa R; de Melo EB; Silva JS; Carvalho I
Bioorg Med Chem; 2015 Nov; 23(21):6815-26. PubMed ID: 26476667
[TBL] [Abstract][Full Text] [Related]
12. The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles.
da Silva EN; Guimarães TT; Menna-Barreto RF; Pinto Mdo C; de Simone CA; Pessoa C; Cavalcanti BC; Sabino JR; Andrade CK; Goulart MO; de Castro SL; Pinto AV
Bioorg Med Chem; 2010 May; 18(9):3224-30. PubMed ID: 20378360
[TBL] [Abstract][Full Text] [Related]
13. Isoxazolylnaphthoquinone effects on the growth of Trypanosoma cruzi.
Amuchástegui PI; Moretti ER; Basso B; Sperandeo N; de Bertorello MM
Rev Argent Microbiol; 1990; 22(4):199-207. PubMed ID: 2129475
[TBL] [Abstract][Full Text] [Related]
14. Natural and synthetic naphthoquinones active against Trypanosoma cruzi: an initial step towards new drugs for Chagas disease.
Salas CO; Faúndez M; Morello A; Maya JD; Tapia RA
Curr Med Chem; 2011; 18(1):144-61. PubMed ID: 21110810
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues.
Ferreira SB; Salomão K; de Carvalho da Silva F; Pinto AV; Kaiser CR; Pinto AC; Ferreira VF; de Castro SL
Eur J Med Chem; 2011 Jul; 46(7):3071-7. PubMed ID: 21450374
[TBL] [Abstract][Full Text] [Related]
16. 2-Phenylaminonaphthoquinones and related compounds: synthesis, trypanocidal and cytotoxic activities.
Sieveking I; Thomas P; Estévez JC; Quiñones N; Cuéllar MA; Villena J; Espinosa-Bustos C; Fierro A; Tapia RA; Maya JD; López-Muñoz R; Cassels BK; Estévez RJ; Salas CO
Bioorg Med Chem; 2014 Sep; 22(17):4609-20. PubMed ID: 25127463
[TBL] [Abstract][Full Text] [Related]
17. Trypanocidal activity of synthetic heterocyclic derivatives of active quinones from Tabebuia sp.
Pinto AV; Pinto CN; Pinto Mdo C; Rita RS; Pezzella CA; de Castro SL
Arzneimittelforschung; 1997 Jan; 47(1):74-9. PubMed ID: 9037448
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and antitrypanosomal activity of some nitrofurazone 1,2,4-triazolic bioisosteric analogues.
Silva FT; Franco CH; Favaro DC; Freitas-Junior LH; Moraes CB; Ferreira EI
Eur J Med Chem; 2016 Oct; 121():553-560. PubMed ID: 27318979
[TBL] [Abstract][Full Text] [Related]
19. Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi.
Wood JM; Satam NS; Almeida RG; Cristani VS; de Lima DP; Dantas-Pereira L; Salomão K; Menna-Barreto RFS; Namboothiri INN; Bower JF; da Silva Júnior EN
Bioorg Med Chem; 2020 Aug; 28(15):115565. PubMed ID: 32631558
[TBL] [Abstract][Full Text] [Related]
20. Effect of 9-hydroxy-α- and 7-hydroxy-β-pyran naphthoquinones on Trypanosoma cruzi and structure-activity relationship studies.
da Rochaa DR; de Souza AM; de Souza AC; Castro HC; Rodrigues CR; Menna-Barreto RF; de Castro SL; Ferreira VF
Med Chem; 2014; 10(6):564-70. PubMed ID: 24372389
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
