These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

674 related articles for article (PubMed ID: 22483801)

  • 1. Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
    Jin T; Perry A; Jiang J; Smith P; Curry JA; Unterholzner L; Jiang Z; Horvath G; Rathinam VA; Johnstone RW; Hornung V; Latz E; Bowie AG; Fitzgerald KA; Xiao TS
    Immunity; 2012 Apr; 36(4):561-71. PubMed ID: 22483801
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.
    Li H; Wang J; Wang J; Cao LS; Wang ZX; Wu JW
    Acta Crystallogr F Struct Biol Commun; 2014 Jan; 70(Pt 1):21-9. PubMed ID: 24419611
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the absent in melanoma 2 (AIM2) pyrin domain provides insights into the mechanisms of AIM2 autoinhibition and inflammasome assembly.
    Jin T; Perry A; Smith P; Jiang J; Xiao TS
    J Biol Chem; 2013 May; 288(19):13225-35. PubMed ID: 23530044
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The emerging role of human PYHIN proteins in innate immunity: implications for health and disease.
    Connolly DJ; Bowie AG
    Biochem Pharmacol; 2014 Dec; 92(3):405-14. PubMed ID: 25199457
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential Activation of NLRP3, AIM2, and IFI16 Inflammasomes in Humans with Acute and Chronic Hepatitis B.
    Chen H; He G; Chen Y; Zhang X; Wu S
    Viral Immunol; 2018 Nov; 31(9):639-645. PubMed ID: 30222506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses.
    Dutta D; Dutta S; Veettil MV; Roy A; Ansari MA; Iqbal J; Chikoti L; Kumar B; Johnson KE; Chandran B
    PLoS Pathog; 2015 Jun; 11(6):e1005030. PubMed ID: 26121674
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The nucleic acid-sensing inflammasomes.
    Xiao TS
    Immunol Rev; 2015 May; 265(1):103-11. PubMed ID: 25879287
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanism for p202-mediated specific inhibition of AIM2 inflammasome activation.
    Yin Q; Sester DP; Tian Y; Hsiao YS; Lu A; Cridland JA; Sagulenko V; Thygesen SJ; Choubey D; Hornung V; Walz T; Stacey KJ; Wu H
    Cell Rep; 2013 Jul; 4(2):327-39. PubMed ID: 23850291
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16.
    Ni X; Ru H; Ma F; Zhao L; Shaw N; Feng Y; Ding W; Gong W; Wang Q; Ouyang S; Cheng G; Liu ZJ
    J Mol Cell Biol; 2016 Feb; 8(1):51-61. PubMed ID: 26246511
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interferon-inducible p200-family protein IFI16, an innate immune sensor for cytosolic and nuclear double-stranded DNA: regulation of subcellular localization.
    Veeranki S; Choubey D
    Mol Immunol; 2012 Jan; 49(4):567-71. PubMed ID: 22137500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of
    Fan Z; Chen R; Yin W; Xie X; Wang S; Hao C
    Viral Immunol; 2023 Sep; 36(7):438-448. PubMed ID: 37585649
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystallographic characterization of mouse AIM2 HIN-200 domain bound to a 15 bp and an 18 bp double-stranded DNA.
    Sung MW; Watts T; Li P
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Sep; 68(Pt 9):1081-4. PubMed ID: 22949200
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16.
    Wang PH; Ye ZW; Deng JJ; Siu KL; Gao WW; Chaudhary V; Cheng Y; Fung SY; Yuen KS; Ho TH; Chan CP; Zhang Y; Kok KH; Yang W; Chan CP; Jin DY
    EMBO Rep; 2018 Oct; 19(10):. PubMed ID: 30104205
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells.
    Bosso M; Prelli Bozzo C; Hotter D; Volcic M; Stürzel CM; Rammelt A; Ni Y; Urban S; Becker M; Schelhaas M; Wittmann S; Christensen MH; Schmidt FI; Gramberg T; Sparrer KMJ; Sauter D; Kirchhoff F
    PLoS Pathog; 2020 Aug; 16(8):e1008752. PubMed ID: 32760121
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural mechanism of DNA recognition by the p204 HIN domain.
    Fan X; Jiang J; Zhao D; Chen F; Ma H; Smith P; Unterholzner L; Xiao TS; Jin T
    Nucleic Acids Res; 2021 Mar; 49(5):2959-2972. PubMed ID: 33619523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts.
    Duan X; Ponomareva L; Veeranki S; Panchanathan R; Dickerson E; Choubey D
    Mol Cancer Res; 2011 May; 9(5):589-602. PubMed ID: 21471287
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes.
    Veeranki S; Duan X; Panchanathan R; Liu H; Choubey D
    PLoS One; 2011; 6(10):e27040. PubMed ID: 22046441
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease.
    Vanhove W; Peeters PM; Staelens D; Schraenen A; Van der Goten J; Cleynen I; De Schepper S; Van Lommel L; Reynaert NL; Schuit F; Van Assche G; Ferrante M; De Hertogh G; Wouters EF; Rutgeerts P; Vermeire S; Nys K; Arijs I
    Inflamm Bowel Dis; 2015 Nov; 21(11):2673-82. PubMed ID: 26313692
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interferon-inducible protein 16: insight into the interaction with tumor suppressor p53.
    Liao JC; Lam R; Brazda V; Duan S; Ravichandran M; Ma J; Xiao T; Tempel W; Zuo X; Wang YX; Chirgadze NY; Arrowsmith CH
    Structure; 2011 Mar; 19(3):418-29. PubMed ID: 21397192
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Impact of nsSNPs in human AIM2 and IFI16 gene: a comprehensive
    Sahoo S; Son S; Lee HK; Lee JY; Gosu V; Shin D
    J Biomol Struct Dyn; 2024 Mar; 42(5):2603-2615. PubMed ID: 37139544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.