These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 22488688)

  • 1. Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.
    Pritchett J; Harvey E; Athwal V; Berry A; Rowe C; Oakley F; Moles A; Mann DA; Bobola N; Sharrocks AD; Thomson BJ; Zaitoun AM; Irving WL; Guha IN; Hanley NA; Hanley KP
    Hepatology; 2012 Sep; 56(3):1108-16. PubMed ID: 22488688
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis.
    Syn WK; Choi SS; Liaskou E; Karaca GF; Agboola KM; Oo YH; Mi Z; Pereira TA; Zdanowicz M; Malladi P; Chen Y; Moylan C; Jung Y; Bhattacharya SD; Teaberry V; Omenetti A; Abdelmalek MF; Guy CD; Adams DH; Kuo PC; Michelotti GA; Whitington PF; Diehl AM
    Hepatology; 2011 Jan; 53(1):106-15. PubMed ID: 20967826
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells.
    Pritchett J; Athwal VS; Harvey E; Martin K; Llewellyn J; Ireland P; Nicolaides A; Humphries MJ; Bobola N; Hanley NA; Piper Hanley K
    PLoS One; 2014; 9(6):e100091. PubMed ID: 24971829
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling.
    Urtasun R; Lopategi A; George J; Leung TM; Lu Y; Wang X; Ge X; Fiel MI; Nieto N
    Hepatology; 2012 Feb; 55(2):594-608. PubMed ID: 21953216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.
    Athwal VS; Pritchett J; Martin K; Llewellyn J; Scott J; Harvey E; Zaitoun AM; Mullan AF; Zeef LAH; Friedman SL; Irving WL; Hanley NA; Guha IN; Piper Hanley K
    Sci Rep; 2018 Dec; 8(1):17905. PubMed ID: 30559459
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Osteopontin promotes collagen I synthesis in hepatic stellate cells by miRNA-129-5p inhibition.
    Chen Y; Ou Y; Dong J; Yang G; Zeng Z; Liu Y; Liu B; Li W; He X; Lan T
    Exp Cell Res; 2018 Jan; 362(2):343-348. PubMed ID: 29196165
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury.
    Arriazu E; Ge X; Leung TM; Magdaleno F; Lopategi A; Lu Y; Kitamura N; Urtasun R; Theise N; Antoine DJ; Nieto N
    Gut; 2017 Jun; 66(6):1123-1137. PubMed ID: 26818617
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease.
    Syn WK; Agboola KM; Swiderska M; Michelotti GA; Liaskou E; Pang H; Xie G; Philips G; Chan IS; Karaca GF; Pereira Tde A; Chen Y; Mi Z; Kuo PC; Choi SS; Guy CD; Abdelmalek MF; Diehl AM
    Gut; 2012 Sep; 61(9):1323-9. PubMed ID: 22427237
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Osteopontin induces ductular reaction contributing to liver fibrosis.
    Wang X; Lopategi A; Ge X; Lu Y; Kitamura N; Urtasun R; Leung TM; Fiel MI; Nieto N
    Gut; 2014 Nov; 63(11):1805-18. PubMed ID: 24496779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice.
    Coombes JD; Swiderska-Syn M; Dollé L; Reid D; Eksteen B; Claridge L; Briones-Orta MA; Shetty S; Oo YH; Riva A; Chokshi S; Papa S; Mi Z; Kuo PC; Williams R; Canbay A; Adams DH; Diehl AM; van Grunsven LA; Choi SS; Syn WK
    Gut; 2015 Jul; 64(7):1120-31. PubMed ID: 24902765
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thrombin cleavage of osteopontin controls activation of hepatic stellate cells and is essential for liver fibrogenesis.
    Cui G; Chen J; Wu Z; Huang H; Wang L; Liang Y; Zeng P; Yang J; Uede T; Diao H
    J Cell Physiol; 2019 Jun; 234(6):8988-8997. PubMed ID: 30350863
    [TBL] [Abstract][Full Text] [Related]  

  • 12.
    Yan J; Hu B; Shi W; Wang X; Shen J; Chen Y; Huang H; Jin L
    Am J Physiol Gastrointest Liver Physiol; 2021 May; 320(5):G720-G728. PubMed ID: 33728992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gant61 ameliorates CCl
    Jiayuan S; Junyan Y; Xiangzhen W; Zuping L; Jian N; Baowei H; Lifang J
    Toxicol Appl Pharmacol; 2020 Jan; 387():114853. PubMed ID: 31816328
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects and regulation of osteopontin in rat hepatic stellate cells.
    Lee SH; Seo GS; Park YN; Yoo TM; Sohn DH
    Biochem Pharmacol; 2004 Dec; 68(12):2367-78. PubMed ID: 15548383
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.
    Athwal VS; Pritchett J; Llewellyn J; Martin K; Camacho E; Raza SM; Phythian-Adams A; Birchall LJ; Mullan AF; Su K; Pearmain L; Dolman G; Zaitoun AM; Friedman SL; MacDonald A; Irving WL; Guha IN; Hanley NA; Piper Hanley K
    EMBO Mol Med; 2017 Dec; 9(12):1696-1710. PubMed ID: 29109128
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fam20C-mediated phosphorylation of osteopontin is critical for its secretion but dispensable for its action as a cytokine in the activation of hepatic stellate cells in liver fibrogenesis.
    Tibaldi E; Brocca A; Sticca A; Gola E; Pizzi M; Bordin L; Pagano MA; Mazzorana M; Donà G; Violi P; Marin O; Romano A; Angeli P; Carraro A; Brunati AM
    FASEB J; 2020 Jan; 34(1):1122-1135. PubMed ID: 31914633
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma.
    Kawai T; Yasuchika K; Ishii T; Miyauchi Y; Kojima H; Yamaoka R; Katayama H; Yoshitoshi EY; Ogiso S; Kita S; Yasuda K; Fukumitsu K; Komori J; Hatano E; Kawaguchi Y; Uemoto S
    Sci Rep; 2016 Jul; 6():30489. PubMed ID: 27457505
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of GSK-3β induces AP-1-mediated osteopontin expression to promote cholestatic liver fibrosis.
    Zhuang S; Hua X; He K; Zhou T; Zhang J; Wu H; Ma X; Xia Q; Zhang J
    FASEB J; 2018 Aug; 32(8):4494-4503. PubMed ID: 29529390
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MicroRNA‑200a suppresses epithelial‑to‑mesenchymal transition in rat hepatic stellate cells via GLI family zinc finger 2.
    Yu F; Zheng Y; Hong W; Chen B; Dong P; Zheng J
    Mol Med Rep; 2015 Dec; 12(6):8121-8. PubMed ID: 26499180
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation.
    Seth D; Duly A; Kuo PC; McCaughan GW; Haber PS
    World J Gastroenterol; 2014 Sep; 20(36):13088-104. PubMed ID: 25278703
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.