187 related articles for article (PubMed ID: 22493258)
1. Y265C DNA polymerase beta knockin mice survive past birth and accumulate base excision repair intermediate substrates.
Senejani AG; Dalal S; Liu Y; Nottoli TP; McGrath JM; Clairmont CS; Sweasy JB
Proc Natl Acad Sci U S A; 2012 Apr; 109(17):6632-7. PubMed ID: 22493258
[TBL] [Abstract][Full Text] [Related]
2. DNA polymerase β-dependent cell survival independent of XRCC1 expression.
Horton JK; Gassman NR; Dunigan BD; Stefanick DF; Wilson SH
DNA Repair (Amst); 2015 Feb; 26():23-9. PubMed ID: 25541391
[TBL] [Abstract][Full Text] [Related]
3. Mammalian DNA beta-polymerase in base excision repair of alkylation damage.
Sobol RW; Wilson SH
Prog Nucleic Acid Res Mol Biol; 2001; 68():57-74. PubMed ID: 11554313
[TBL] [Abstract][Full Text] [Related]
4. DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model.
Paluri SL; Burak M; Senejani AG; Levinson M; Rahim T; Clairmont K; Kashgarian M; Alvarado-Cruz I; Meas R; Cardó-Vila M; Zeiss C; Maher S; Bothwell ALM; Coskun E; Kant M; Jaruga P; Dizdaroglu M; Stephen Lloyd R; Sweasy JB
DNA Repair (Amst); 2021 Sep; 105():103152. PubMed ID: 34186496
[TBL] [Abstract][Full Text] [Related]
5. Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens.
Cabelof DC; Guo Z; Raffoul JJ; Sobol RW; Wilson SH; Richardson A; Heydari AR
Cancer Res; 2003 Sep; 63(18):5799-807. PubMed ID: 14522902
[TBL] [Abstract][Full Text] [Related]
6. Mutation of DNA Polymerase β R137Q Results in Retarded Embryo Development Due to Impaired DNA Base Excision Repair in Mice.
Pan F; Zhao J; Zhou T; Kuang Z; Dai H; Wu H; Sun H; Zhou X; Wu X; Hu Z; He L; Shen B; Guo Z
Sci Rep; 2016 Jun; 6():28614. PubMed ID: 27358192
[TBL] [Abstract][Full Text] [Related]
7. Colon cancer-associated DNA polymerase β variant induces genomic instability and cellular transformation.
Nemec AA; Donigan KA; Murphy DL; Jaeger J; Sweasy JB
J Biol Chem; 2012 Jul; 287(28):23840-9. PubMed ID: 22573322
[TBL] [Abstract][Full Text] [Related]
8. Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage.
Ochs K; Sobol RW; Wilson SH; Kaina B
Cancer Res; 1999 Apr; 59(7):1544-51. PubMed ID: 10197627
[TBL] [Abstract][Full Text] [Related]
9. Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo.
Cabelof DC; Raffoul JJ; Yanamadala S; Guo Z; Heydari AR
Carcinogenesis; 2002 Sep; 23(9):1419-25. PubMed ID: 12189182
[TBL] [Abstract][Full Text] [Related]
10. The K167I variant of DNA polymerase β that is found in Esophageal Carcinoma patients impairs polymerase activity and BER.
Wang Y; Zang W; Du Y; Chen X; Zhao G
Sci Rep; 2015 Nov; 5():15986. PubMed ID: 26527528
[TBL] [Abstract][Full Text] [Related]
11. DNA synthesis and dRPase activities of polymerase beta are both essential for single-nucleotide patch base excision repair in mammalian cell extracts.
Podlutsky AJ; Dianova II; Wilson SH; Bohr VA; Dianov GL
Biochemistry; 2001 Jan; 40(3):809-13. PubMed ID: 11170398
[TBL] [Abstract][Full Text] [Related]
12. The E295K DNA polymerase beta gastric cancer-associated variant interferes with base excision repair and induces cellular transformation.
Lang T; Dalal S; Chikova A; DiMaio D; Sweasy JB
Mol Cell Biol; 2007 Aug; 27(15):5587-96. PubMed ID: 17526740
[TBL] [Abstract][Full Text] [Related]
13. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress.
Sobol RW; Watson DE; Nakamura J; Yakes FM; Hou E; Horton JK; Ladapo J; Van Houten B; Swenberg JA; Tindall KR; Samson LD; Wilson SH
Proc Natl Acad Sci U S A; 2002 May; 99(10):6860-5. PubMed ID: 11983862
[TBL] [Abstract][Full Text] [Related]
14. DNA polymerase beta is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide.
Fortini P; Pascucci B; Belisario F; Dogliotti E
Nucleic Acids Res; 2000 Aug; 28(16):3040-6. PubMed ID: 10931918
[TBL] [Abstract][Full Text] [Related]
15. A germline polymorphism of DNA polymerase beta induces genomic instability and cellular transformation.
Yamtich J; Nemec AA; Keh A; Sweasy JB
PLoS Genet; 2012; 8(11):e1003052. PubMed ID: 23144635
[TBL] [Abstract][Full Text] [Related]
16. Human DNA polymerase beta polymorphism, Arg137Gln, impairs its polymerase activity and interaction with PCNA and the cellular base excision repair capacity.
Guo Z; Zheng L; Dai H; Zhou M; Xu H; Shen B
Nucleic Acids Res; 2009 Jun; 37(10):3431-41. PubMed ID: 19336415
[TBL] [Abstract][Full Text] [Related]
17. The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 cells.
Clairmont CA; Narayanan L; Sun KW; Glazer PM; Sweasy JB
Proc Natl Acad Sci U S A; 1999 Aug; 96(17):9580-5. PubMed ID: 10449735
[TBL] [Abstract][Full Text] [Related]
18. The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency.
Nemec AA; Murphy DL; Donigan KA; Sweasy JB
J Biol Chem; 2014 May; 289(20):13708-16. PubMed ID: 24668809
[TBL] [Abstract][Full Text] [Related]
19. R152C DNA Pol β mutation impairs base excision repair and induces cellular transformation.
Zhou T; Pan F; Cao Y; Han Y; Zhao J; Sun H; Zhou X; Wu X; He L; Hu Z; Chen H; Shen B; Guo Z
Oncotarget; 2016 Feb; 7(6):6902-15. PubMed ID: 26760506
[TBL] [Abstract][Full Text] [Related]
20. Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair.
Horton JK; Prasad R; Hou E; Wilson SH
J Biol Chem; 2000 Jan; 275(3):2211-8. PubMed ID: 10636928
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
