302 related articles for article (PubMed ID: 22493445)
1. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.
van Meeteren LA; Thorikay M; Bergqvist S; Pardali E; Stampino CG; Hu-Lowe D; Goumans MJ; ten Dijke P
J Biol Chem; 2012 May; 287(22):18551-61. PubMed ID: 22493445
[TBL] [Abstract][Full Text] [Related]
2. Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells.
Upton PD; Davies RJ; Trembath RC; Morrell NW
J Biol Chem; 2009 Jun; 284(23):15794-804. PubMed ID: 19366699
[TBL] [Abstract][Full Text] [Related]
3. BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II.
Kim JH; Peacock MR; George SC; Hughes CC
Angiogenesis; 2012 Sep; 15(3):497-509. PubMed ID: 22622516
[TBL] [Abstract][Full Text] [Related]
4. BMP9 (Bone Morphogenetic Protein-9)/Alk1 (Activin-Like Kinase Receptor Type I) Signaling Prevents Hyperglycemia-Induced Vascular Permeability.
Akla N; Viallard C; Popovic N; Lora Gil C; Sapieha P; Larrivée B
Arterioscler Thromb Vasc Biol; 2018 Aug; 38(8):1821-1836. PubMed ID: 29880487
[TBL] [Abstract][Full Text] [Related]
5. Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.
Mitrofan CG; Appleby SL; Nash GB; Mallat Z; Chilvers ER; Upton PD; Morrell NW
J Biol Chem; 2017 Aug; 292(33):13714-13726. PubMed ID: 28646109
[TBL] [Abstract][Full Text] [Related]
6. Regulation of the ALK1 ligands, BMP9 and BMP10.
Li W; Salmon RM; Jiang H; Morrell NW
Biochem Soc Trans; 2016 Aug; 44(4):1135-41. PubMed ID: 27528761
[TBL] [Abstract][Full Text] [Related]
7. Endoglin requirement for BMP9 signaling in endothelial cells reveals new mechanism of action for selective anti-endoglin antibodies.
Nolan-Stevaux O; Zhong W; Culp S; Shaffer K; Hoover J; Wickramasinghe D; Ruefli-Brasse A
PLoS One; 2012; 7(12):e50920. PubMed ID: 23300529
[TBL] [Abstract][Full Text] [Related]
8. Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1.
Yao Y; Zebboudj AF; Shao E; Perez M; Boström K
J Biol Chem; 2006 Nov; 281(45):33921-30. PubMed ID: 16950789
[TBL] [Abstract][Full Text] [Related]
9. Specificity and structure of a high affinity activin receptor-like kinase 1 (ALK1) signaling complex.
Townson SA; Martinez-Hackert E; Greppi C; Lowden P; Sako D; Liu J; Ucran JA; Liharska K; Underwood KW; Seehra J; Kumar R; Grinberg AV
J Biol Chem; 2012 Aug; 287(33):27313-25. PubMed ID: 22718755
[TBL] [Abstract][Full Text] [Related]
10. Serum/glucocorticoid-regulated kinase 1 as a novel transcriptional target of bone morphogenetic protein-ALK1 receptor signaling in vascular endothelial cells.
Araki M; Hisamitsu T; Kinugasa-Katayama Y; Tanaka T; Harada Y; Nakao S; Hanada S; Ishii S; Fujita M; Kawamura T; Saito Y; Nishiyama K; Watanabe Y; Nakagawa O
Angiogenesis; 2018 May; 21(2):415-423. PubMed ID: 29478089
[TBL] [Abstract][Full Text] [Related]
11. Homeobox D3, A Novel Link Between Bone Morphogenetic Protein 9 and Transforming Growth Factor Beta 1 Signaling.
Wang L; Yao J; Yu T; Zhang D; Qiao X; Yao Z; Wu X; Zhang L; Boström KI; Yao Y
J Mol Biol; 2020 Mar; 432(7):2030-2041. PubMed ID: 32061928
[TBL] [Abstract][Full Text] [Related]
12. BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis.
Scharpfenecker M; van Dinther M; Liu Z; van Bezooijen RL; Zhao Q; Pukac L; Löwik CW; ten Dijke P
J Cell Sci; 2007 Mar; 120(Pt 6):964-72. PubMed ID: 17311849
[TBL] [Abstract][Full Text] [Related]
13. Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains.
Kienast Y; Jucknischke U; Scheiblich S; Thier M; de Wouters M; Haas A; Lehmann C; Brand V; Bernicke D; Honold K; Lorenz S
J Biol Chem; 2016 Feb; 291(7):3395-410. PubMed ID: 26677222
[TBL] [Abstract][Full Text] [Related]
14. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells.
David L; Mallet C; Mazerbourg S; Feige JJ; Bailly S
Blood; 2007 Mar; 109(5):1953-61. PubMed ID: 17068149
[TBL] [Abstract][Full Text] [Related]
15. BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration.
Ntumba K; Akla N; Oh SP; Eichmann A; Larrivée B
Oncotarget; 2016 Aug; 7(35):55957-55969. PubMed ID: 27517154
[TBL] [Abstract][Full Text] [Related]
16. BMP9 and BMP10 are critical for postnatal retinal vascular remodeling.
Ricard N; Ciais D; Levet S; Subileau M; Mallet C; Zimmers TA; Lee SJ; Bidart M; Feige JJ; Bailly S
Blood; 2012 Jun; 119(25):6162-71. PubMed ID: 22566602
[TBL] [Abstract][Full Text] [Related]
17. Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms.
Salmon RM; Guo J; Wood JH; Tong Z; Beech JS; Lawera A; Yu M; Grainger DJ; Reckless J; Morrell NW; Li W
Nat Commun; 2020 Apr; 11(1):1621. PubMed ID: 32238803
[TBL] [Abstract][Full Text] [Related]
18. ALK1 Loss Results in Vascular Hyperplasia in Mice and Humans Through PI3K Activation.
Alsina-Sanchís E; García-Ibáñez Y; Figueiredo AM; Riera-Domingo C; Figueras A; Matias-Guiu X; Casanovas O; Botella LM; Pujana MA; Riera-Mestre A; Graupera M; Viñals F
Arterioscler Thromb Vasc Biol; 2018 May; 38(5):1216-1229. PubMed ID: 29449337
[TBL] [Abstract][Full Text] [Related]
19. TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells.
Luo J; Tang M; Huang J; He BC; Gao JL; Chen L; Zuo GW; Zhang W; Luo Q; Shi Q; Zhang BQ; Bi Y; Luo X; Jiang W; Su Y; Shen J; Kim SH; Huang E; Gao Y; Zhou JZ; Yang K; Luu HH; Pan X; Haydon RC; Deng ZL; He TC
J Biol Chem; 2010 Sep; 285(38):29588-98. PubMed ID: 20628059
[TBL] [Abstract][Full Text] [Related]
20. BMP9 Induces Cord Blood-Derived Endothelial Progenitor Cell Differentiation and Ischemic Neovascularization via ALK1.
Kim J; Kim M; Jeong Y; Lee WB; Park H; Kwon JY; Kim YM; Hwang D; Kwon YG
Arterioscler Thromb Vasc Biol; 2015 Sep; 35(9):2020-31. PubMed ID: 26229139
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
