BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 22493445)

  • 21. ALK1-Fc inhibits multiple mediators of angiogenesis and suppresses tumor growth.
    Mitchell D; Pobre EG; Mulivor AW; Grinberg AV; Castonguay R; Monnell TE; Solban N; Ucran JA; Pearsall RS; Underwood KW; Seehra J; Kumar R
    Mol Cancer Ther; 2010 Feb; 9(2):379-88. PubMed ID: 20124460
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction.
    Lebrin F; Goumans MJ; Jonker L; Carvalho RL; Valdimarsdottir G; Thorikay M; Mummery C; Arthur HM; ten Dijke P
    EMBO J; 2004 Oct; 23(20):4018-28. PubMed ID: 15385967
    [TBL] [Abstract][Full Text] [Related]  

  • 23. BMP10 functions independently from BMP9 for the development of a proper arteriovenous network.
    Choi H; Kim BG; Kim YH; Lee SJ; Lee YJ; Oh SP
    Angiogenesis; 2023 Feb; 26(1):167-186. PubMed ID: 36348215
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Expression of vascular endothelial growth factor is coordinately regulated by the activin-like kinase receptors 1 and 5 in endothelial cells.
    Shao ES; Lin L; Yao Y; Boström KI
    Blood; 2009 Sep; 114(10):2197-206. PubMed ID: 19506300
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies.
    Hu-Lowe DD; Chen E; Zhang L; Watson KD; Mancuso P; Lappin P; Wickman G; Chen JH; Wang J; Jiang X; Amundson K; Simon R; Erbersdobler A; Bergqvist S; Feng Z; Swanson TA; Simmons BH; Lippincott J; Casperson GF; Levin WJ; Stampino CG; Shalinsky DR; Ferrara KW; Fiedler W; Bertolini F
    Cancer Res; 2011 Feb; 71(4):1362-73. PubMed ID: 21212415
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors.
    Hawinkels LJ; de Vinuesa AG; Paauwe M; Kruithof-de Julio M; Wiercinska E; Pardali E; Mezzanotte L; Keereweer S; Braumuller TM; Heijkants RC; Jonkers J; Löwik CW; Goumans MJ; ten Hagen TL; ten Dijke P
    Clin Cancer Res; 2016 Jan; 22(1):96-106. PubMed ID: 26373572
    [TBL] [Abstract][Full Text] [Related]  

  • 27. BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer.
    Ouarné M; Bouvard C; Boneva G; Mallet C; Ribeiro J; Desroches-Castan A; Soleilhac E; Tillet E; Peyruchaud O; Bailly S
    J Exp Clin Cancer Res; 2018 Aug; 37(1):209. PubMed ID: 30165893
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.
    Cunha SI; Pardali E; Thorikay M; Anderberg C; Hawinkels L; Goumans MJ; Seehra J; Heldin CH; ten Dijke P; Pietras K
    J Exp Med; 2010 Jan; 207(1):85-100. PubMed ID: 20065063
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Key role of the endothelial TGF-β/ALK1/endoglin signaling pathway in humans and rodents pulmonary hypertension.
    Gore B; Izikki M; Mercier O; Dewachter L; Fadel E; Humbert M; Dartevelle P; Simonneau G; Naeije R; Lebrin F; Eddahibi S
    PLoS One; 2014; 9(6):e100310. PubMed ID: 24956016
    [TBL] [Abstract][Full Text] [Related]  

  • 30. ALK1 regulates the internalization of endoglin and the type III TGF-β receptor.
    Tazat K; Pomeraniec-Abudy L; Hector-Greene M; Szilágyi SS; Sharma S; Cai EM; Corona AL; Ehrlich M; Blobe GC; Henis YI
    Mol Biol Cell; 2021 Apr; 32(7):605-621. PubMed ID: 33566682
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis.
    Somekawa S; Imagawa K; Hayashi H; Sakabe M; Ioka T; Sato GE; Inada K; Iwamoto T; Mori T; Uemura S; Nakagawa O; Saito Y
    Proc Natl Acad Sci U S A; 2012 Jul; 109(30):12064-9. PubMed ID: 22783020
    [TBL] [Abstract][Full Text] [Related]  

  • 32. EPDR1 is a noncanonical effector of insulin-mediated angiogenesis regulated by an endothelial-specific TGF-β receptor complex.
    Ahmed T; Flores PC; Pan CC; Ortiz HR; Lee YS; Langlais PR; Mythreye K; Lee NY
    J Biol Chem; 2022 Sep; 298(9):102297. PubMed ID: 35872017
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Bone morphogenetic protein-9 is a circulating vascular quiescence factor.
    David L; Mallet C; Keramidas M; Lamandé N; Gasc JM; Dupuis-Girod S; Plauchu H; Feige JJ; Bailly S
    Circ Res; 2008 Apr; 102(8):914-22. PubMed ID: 18309101
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A Bone Morphogenetic Protein (BMP)-derived Peptide Based on the Type I Receptor-binding Site Modifies Cell-type Dependent BMP Signalling.
    Tong Z; Guo J; Glen RC; Morrell NW; Li W
    Sci Rep; 2019 Sep; 9(1):13446. PubMed ID: 31530856
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes.
    Mendez PL; Obendorf L; Jatzlau J; Burdzinski W; Reichenbach M; Nageswaran V; Haghikia A; Stangl V; Hiepen C; Knaus P
    BMC Biol; 2022 Sep; 20(1):210. PubMed ID: 36171573
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.
    Yoshimatsu Y; Lee YG; Akatsu Y; Taguchi L; Suzuki HI; Cunha SI; Maruyama K; Suzuki Y; Yamazaki T; Katsura A; Oh SP; Zimmers TA; Lee SJ; Pietras K; Koh GY; Miyazono K; Watabe T
    Proc Natl Acad Sci U S A; 2013 Nov; 110(47):18940-5. PubMed ID: 24133138
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations.
    Ricard N; Bidart M; Mallet C; Lesca G; Giraud S; Prudent R; Feige JJ; Bailly S
    Blood; 2010 Sep; 116(9):1604-12. PubMed ID: 20501893
    [TBL] [Abstract][Full Text] [Related]  

  • 38. SEMA3G regulates BMP9 inhibition of VEGF-mediated migration and network formation in pulmonary endothelial cells.
    Mirza SL; Upton PD; Hodgson J; Gräf S; Morrell NW; Dunmore BJ
    Vascul Pharmacol; 2024 Jun; 155():107381. PubMed ID: 38795838
    [TBL] [Abstract][Full Text] [Related]  

  • 39. BMP9 regulates endoglin-dependent chemokine responses in endothelial cells.
    Young K; Conley B; Romero D; Tweedie E; O'Neill C; Pinz I; Brogan L; Lindner V; Liaw L; Vary CP
    Blood; 2012 Nov; 120(20):4263-73. PubMed ID: 23018639
    [TBL] [Abstract][Full Text] [Related]  

  • 40. ALK1 signaling in development and disease: new paradigms.
    Roman BL; Hinck AP
    Cell Mol Life Sci; 2017 Dec; 74(24):4539-4560. PubMed ID: 28871312
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.