These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 22495586)

  • 1. Phosphodiesterase-4 inhibition as a therapeutic approach to treat capillary leakage in systemic inflammation.
    Schick MA; Wunder C; Wollborn J; Roewer N; Waschke J; Germer CT; Schlegel N
    J Physiol; 2012 Jun; 590(11):2693-708. PubMed ID: 22495586
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphodiesterase-4 inhibition reduces ECLS-induced vascular permeability and improves microcirculation in a rodent model of extracorporeal resuscitation.
    Wollborn J; Siemering S; Steiger C; Buerkle H; Goebel U; Schick MA
    Am J Physiol Heart Circ Physiol; 2019 Mar; 316(3):H751-H761. PubMed ID: 30681364
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis.
    Flemming S; Schlegel N; Wunder C; Meir M; Baar W; Wollborn J; Roewer N; Germer CT; Schick MA
    Shock; 2014 Jun; 41(6):537-45. PubMed ID: 24569506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Roflumilast inhibits leukocyte-endothelial cell interactions, expression of adhesion molecules and microvascular permeability.
    Sanz MJ; Cortijo J; Taha MA; Cerdá-Nicolás M; Schatton E; Burgbacher B; Klar J; Tenor H; Schudt C; Issekutz AC; Hatzelmann A; Morcillo EJ
    Br J Pharmacol; 2007 Oct; 152(4):481-92. PubMed ID: 17704822
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The unrecognized effects of phosphodiesterase 4 on epithelial cells in pulmonary inflammation.
    Konrad FM; Bury A; Schick MA; Ngamsri KC; Reutershan J
    PLoS One; 2015; 10(4):e0121725. PubMed ID: 25909327
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cardiovascular effects of Roflumilast during sepsis: Risks or benefits?
    Ferreira Alves G; Oliveira JG; Nakashima MA; Delfrate G; Sordi R; Assreuy J; da Silva-Santos JE; Collino M; Fernandes D
    Eur J Pharmacol; 2024 Nov; 983():177015. PubMed ID: 39332796
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lipopolysaccharide-induced endothelial barrier breakdown is cyclic adenosine monophosphate dependent in vivo and in vitro.
    Schlegel N; Baumer Y; Drenckhahn D; Waschke J
    Crit Care Med; 2009 May; 37(5):1735-43. PubMed ID: 19325485
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Phosphodiesterase 4 inhibition for treatment of endothelial barrier and microcirculation disorders in sepsis].
    Wollborn J; Schlegel N; Schick MA
    Anaesthesist; 2017 May; 66(5):347-352. PubMed ID: 28429038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation.
    Dozier KC; Cureton EL; Kwan RO; Curran B; Sadjadi J; Victorino GP
    Peptides; 2009 Sep; 30(9):1735-41. PubMed ID: 19560500
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of rolipram and roflumilast, phosphodiesterase-4 inhibitors, on hypertension-induced defects in memory function in rats.
    Jabaris SG; Sumathy H; Kumar RS; Narayanan S; Thanikachalam S; Babu CS
    Eur J Pharmacol; 2015 Jan; 746():138-47. PubMed ID: 25446433
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphodiesterase 4 inhibition attenuates plasma volume loss and transvascular exchange in volume-expanded mice.
    Lin YC; Adamson RH; Clark JF; Reed RK; Curry FR
    J Physiol; 2012 Jan; 590(2):309-22. PubMed ID: 22083598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roflumilast Reduces Cerebral Inflammation in a Rat Model of Experimental Subarachnoid Hemorrhage.
    Wu Q; Qi L; Li H; Mao L; Yang M; Xie R; Yang X; Wang J; Zhang Z; Kong J; Sun B
    Inflammation; 2017 Aug; 40(4):1245-1253. PubMed ID: 28451841
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
    Jabaris SS; Sumathy H; Girish R; Narayanan S; Sugumar M; Saravana Babu C; Thanikachalam S; Thanikachalam M
    Brain Res; 2015 Oct; 1622():279-91. PubMed ID: 26168894
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Effect of Roflumilast on Lipopolysaccharide-induced Acute Lung Injury During Neutropenia Recovery in Mice.
    Kim KY; Kim YA; Joo HS; Kim JW
    In Vivo; 2024; 38(3):1127-1132. PubMed ID: 38688656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of tadalafil (PDE5 inhibitor) and roflumilast (PDE4 inhibitor) on airway reactivity and markers of inflammation in ovalbumin-induced airway hyperresponsiveness in guinea pigs.
    Mokry J; Urbanova A; Medvedova I; Kertys M; Mikolka P; Kosutova P; Mokra D
    J Physiol Pharmacol; 2017 Oct; 68(5):721-730. PubMed ID: 29375047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Roflumilast: clinical review of a new option for the treatment of inflammation in COPD].
    Martínez FJ
    Arch Bronconeumol; 2010 Nov; 46 Suppl 9():8-11. PubMed ID: 21320811
    [No Abstract]   [Full Text] [Related]  

  • 17. Phosphodiestrase-1 and 4 inhibitors ameliorate liver fibrosis in rats: Modulation of cAMP/CREB/TLR4 inflammatory and fibrogenic pathways.
    Essam RM; Ahmed LA; Abdelsalam RM; El-Khatib AS
    Life Sci; 2019 Apr; 222():245-254. PubMed ID: 30858122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PDE4 inhibitors roflumilast and rolipram augment PGE2 inhibition of TGF-{beta}1-stimulated fibroblasts.
    Togo S; Liu X; Wang X; Sugiura H; Kamio K; Kawasaki S; Kobayashi T; Ertl RF; Ahn Y; Holz O; Magnussen H; Fredriksson K; Skold CM; Rennard SI
    Am J Physiol Lung Cell Mol Physiol; 2009 Jun; 296(6):L959-69. PubMed ID: 19304913
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Direct Inhibitory Effect of the PDE4 Inhibitor Roflumilast on Neutrophil Migration in Chronic Obstructive Pulmonary Disease.
    Dunne AE; Kawamatawong T; Fenwick PS; Davies CM; Tullett H; Barnes PJ; Donnelly LE
    Am J Respir Cell Mol Biol; 2019 Apr; 60(4):445-453. PubMed ID: 30395484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways.
    Kwak HJ; Park KM; Choi HE; Chung KS; Lim HJ; Park HY
    Cell Signal; 2008 May; 20(5):803-14. PubMed ID: 18276108
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.