188 related articles for article (PubMed ID: 22496447)
1. Invariant gly residue is important for α-defensin folding, dimerization, and function: a case study of the human neutrophil α-defensin HNP1.
Zhao L; Ericksen B; Wu X; Zhan C; Yuan W; Li X; Pazgier M; Lu W
J Biol Chem; 2012 Jun; 287(23):18900-12. PubMed ID: 22496447
[TBL] [Abstract][Full Text] [Related]
2. Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
Xie C; Prahl A; Ericksen B; Wu Z; Zeng P; Li X; Lu WY; Lubkowski J; Lu W
J Biol Chem; 2005 Sep; 280(38):32921-9. PubMed ID: 15894545
[TBL] [Abstract][Full Text] [Related]
3. Functional determinants of human enteric α-defensin HD5: crucial role for hydrophobicity at dimer interface.
Rajabi M; Ericksen B; Wu X; de Leeuw E; Zhao L; Pazgier M; Lu W
J Biol Chem; 2012 Jun; 287(26):21615-27. PubMed ID: 22573326
[TBL] [Abstract][Full Text] [Related]
4. Single, double and quadruple alanine substitutions at oligomeric interfaces identify hydrophobicity as the key determinant of human neutrophil alpha defensin HNP1 function.
Zhao L; Tolbert WD; Ericksen B; Zhan C; Wu X; Yuan W; Li X; Pazgier M; Lu W
PLoS One; 2013; 8(11):e78937. PubMed ID: 24236072
[TBL] [Abstract][Full Text] [Related]
5. Systematic mutational analysis of human neutrophil α-defensin HNP4.
Hu H; Di B; Tolbert WD; Gohain N; Yuan W; Gao P; Ma B; He Q; Pazgier M; Zhao L; Lu W
Biochim Biophys Acta Biomembr; 2019 Apr; 1861(4):835-844. PubMed ID: 30658057
[TBL] [Abstract][Full Text] [Related]
6. Sometimes it takes two to tango: contributions of dimerization to functions of human α-defensin HNP1 peptide.
Pazgier M; Wei G; Ericksen B; Jung G; Wu Z; de Leeuw E; Yuan W; Szmacinski H; Lu WY; Lubkowski J; Lehrer RI; Lu W
J Biol Chem; 2012 Mar; 287(12):8944-53. PubMed ID: 22270360
[TBL] [Abstract][Full Text] [Related]
7. Impact of pro segments on the folding and function of human neutrophil alpha-defensins.
Wu Z; Li X; Ericksen B; de Leeuw E; Zou G; Zeng P; Xie C; Li C; Lubkowski J; Lu WY; Lu W
J Mol Biol; 2007 Apr; 368(2):537-49. PubMed ID: 17355880
[TBL] [Abstract][Full Text] [Related]
8. Trp-26 imparts functional versatility to human alpha-defensin HNP1.
Wei G; Pazgier M; de Leeuw E; Rajabi M; Li J; Zou G; Jung G; Yuan W; Lu WY; Lehrer RI; Lu W
J Biol Chem; 2010 May; 285(21):16275-85. PubMed ID: 20220136
[TBL] [Abstract][Full Text] [Related]
9. Why is the Arg5-Glu13 salt bridge conserved in mammalian alpha-defensins?
Wu Z; Li X; de Leeuw E; Ericksen B; Lu W
J Biol Chem; 2005 Dec; 280(52):43039-47. PubMed ID: 16246847
[TBL] [Abstract][Full Text] [Related]
10. Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs.
Zou G; de Leeuw E; Li C; Pazgier M; Li C; Zeng P; Lu WY; Lubkowski J; Lu W
J Biol Chem; 2007 Jul; 282(27):19653-65. PubMed ID: 17452329
[TBL] [Abstract][Full Text] [Related]
11. Through the looking glass, mechanistic insights from enantiomeric human defensins.
Wei G; de Leeuw E; Pazgier M; Yuan W; Zou G; Wang J; Ericksen B; Lu WY; Lehrer RI; Lu W
J Biol Chem; 2009 Oct; 284(42):29180-92. PubMed ID: 19640840
[TBL] [Abstract][Full Text] [Related]
12. The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability.
Rajabi M; de Leeuw E; Pazgier M; Li J; Lubkowski J; Lu W
J Biol Chem; 2008 Aug; 283(31):21509-18. PubMed ID: 18499668
[TBL] [Abstract][Full Text] [Related]
13. From pro defensins to defensins: synthesis and characterization of human neutrophil pro alpha-defensin-1 and its mature domain.
Wu Z; Prahl A; Powell R; Ericksen B; Lubkowski J; Lu W
J Pept Res; 2003 Aug; 62(2):53-62. PubMed ID: 12823617
[TBL] [Abstract][Full Text] [Related]
14. The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.
Andersson HS; Figueredo SM; Haugaard-Kedström LM; Bengtsson E; Daly NL; Qu X; Craik DJ; Ouellette AJ; Rosengren KJ
Amino Acids; 2012 Oct; 43(4):1471-83. PubMed ID: 22286872
[TBL] [Abstract][Full Text] [Related]
15. High fidelity processing and activation of the human α-defensin HNP1 precursor by neutrophil elastase and proteinase 3.
Tongaonkar P; Golji AE; Tran P; Ouellette AJ; Selsted ME
PLoS One; 2012; 7(3):e32469. PubMed ID: 22448222
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, structure, and activities of an oral mucosal alpha-defensin from rhesus macaque.
Vasudevan S; Yuan J; Osapay G; Tran P; Tai K; Liang W; Kumar V; Selsted ME; Cocco MJ
J Biol Chem; 2008 Dec; 283(51):35869-77. PubMed ID: 18930922
[TBL] [Abstract][Full Text] [Related]
17. Large-scale synthesis and functional elements for the antimicrobial activity of defensins.
Raj PA; Antonyraj KJ; Karunakaran T
Biochem J; 2000 May; 347 Pt 3(Pt 3):633-41. PubMed ID: 10769165
[TBL] [Abstract][Full Text] [Related]
18. Antimicrobial activity of human α-defensin 6 analogs: insights into the physico-chemical reasons behind weak bactericidal activity of HD6 in vitro.
Mathew B; Nagaraj R
J Pept Sci; 2015 Nov; 21(11):811-8. PubMed ID: 26400692
[TBL] [Abstract][Full Text] [Related]
19. Hydrophobic determinants of α-defensin bactericidal activity.
Tai KP; Le VV; Selsted ME; Ouellette AJ
Infect Immun; 2014 Jun; 82(6):2195-202. PubMed ID: 24614658
[TBL] [Abstract][Full Text] [Related]
20. Effects of single D-amino acid substitutions on disruption of beta-sheet structure and hydrophobicity in cyclic 14-residue antimicrobial peptide analogs related to gramicidin S.
Lee DL; Powers JP; Pflegerl K; Vasil ML; Hancock RE; Hodges RS
J Pept Res; 2004 Feb; 63(2):69-84. PubMed ID: 15009528
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]