BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 22496568)

  • 21. N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice.
    Baek RC; Kasperzyk JL; Platt FM; Seyfried TN
    Neurochem Int; 2008 May; 52(6):1125-33. PubMed ID: 18207611
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Diminished parkin solubility and co-localization with intraneuronal amyloid-β are associated with autophagic defects in Alzheimer's disease.
    Lonskaya I; Shekoyan AR; Hebron ML; Desforges N; Algarzae NK; Moussa CE
    J Alzheimers Dis; 2013; 33(1):231-47. PubMed ID: 22954671
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Evidence that small molecule enhancement of β-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aβ.
    Knight EM; Williams HN; Stevens AC; Kim SH; Kottwitz JC; Morant AD; Steele JW; Klein WL; Yanagisawa K; Boyd RE; Lockhart DJ; Sjoberg ER; Ehrlich ME; Wustman BA; Gandy S
    Mol Psychiatry; 2015 Feb; 20(1):109-17. PubMed ID: 25349165
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Thymic involution and corticosterone level in Sandhoff disease model mice: new aspects the pathogenesis of GM2 gangliosidosis.
    Matsuoka K; Tsuji D; Taki T; Itoh K
    J Inherit Metab Dis; 2011 Oct; 34(5):1061-8. PubMed ID: 21598013
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Comparative analysis of brain lipids in mice, cats, and humans with Sandhoff disease.
    Baek RC; Martin DR; Cox NR; Seyfried TN
    Lipids; 2009 Mar; 44(3):197-205. PubMed ID: 19034545
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein.
    Kaur G; Pawlik M; Gandy SE; Ehrlich ME; Smiley JF; Levy E
    Mol Psychiatry; 2017 Jul; 22(7):981-989. PubMed ID: 27777419
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Composition of gangliosides and neutral glycosphingolipids of brain in classical Tay-Sachs and Sandhoff disease: more lyso-GM2 in Sandhoff disease?
    Rosengren B; Månsson JE; Svennerholm L
    J Neurochem; 1987 Sep; 49(3):834-40. PubMed ID: 3612128
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Metabolic correction in microglia derived from Sandhoff disease model mice.
    Tsuji D; Kuroki A; Ishibashi Y; Itakura T; Itoh K
    J Neurochem; 2005 Sep; 94(6):1631-8. PubMed ID: 16092933
    [TBL] [Abstract][Full Text] [Related]  

  • 29. GM2 ganglioside accumulation causes neuroinflammation and behavioral alterations in a mouse model of early onset Tay-Sachs disease.
    Demir SA; Timur ZK; Ateş N; Martínez LA; Seyrantepe V
    J Neuroinflammation; 2020 Sep; 17(1):277. PubMed ID: 32951593
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Reversibility of neuropathology in Tay-Sachs-related diseases.
    Cachón-González MB; Wang SZ; Ziegler R; Cheng SH; Cox TM
    Hum Mol Genet; 2014 Feb; 23(3):730-48. PubMed ID: 24057669
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cerebral organoids derived from Sandhoff disease-induced pluripotent stem cells exhibit impaired neurodifferentiation.
    Allende ML; Cook EK; Larman BC; Nugent A; Brady JM; Golebiowski D; Sena-Esteves M; Tifft CJ; Proia RL
    J Lipid Res; 2018 Mar; 59(3):550-563. PubMed ID: 29358305
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Abeta polymerization through interaction with membrane gangliosides.
    Matsuzaki K; Kato K; Yanagisawa K
    Biochim Biophys Acta; 2010 Aug; 1801(8):868-77. PubMed ID: 20117237
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.
    España J; Giménez-Llort L; Valero J; Miñano A; Rábano A; Rodriguez-Alvarez J; LaFerla FM; Saura CA
    Biol Psychiatry; 2010 Mar; 67(6):513-21. PubMed ID: 19664757
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Endogenous Murine Amyloid-β Peptide Assembles into Aggregates in the Aged C57BL/6J Mouse Suggesting These Animals as a Model to Study Pathogenesis of Amyloid-β Plaque Formation.
    Ahlemeyer B; Halupczok S; Rodenberg-Frank E; Valerius KP; Baumgart-Vogt E
    J Alzheimers Dis; 2018; 61(4):1425-1450. PubMed ID: 29376876
    [TBL] [Abstract][Full Text] [Related]  

  • 35. APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.
    Maulik M; Peake K; Chung J; Wang Y; Vance JE; Kar S
    Hum Mol Genet; 2015 Dec; 24(24):7132-50. PubMed ID: 26433932
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of calcium uptake via the sarco/endoplasmic reticulum Ca2+-ATPase in a mouse model of Sandhoff disease and prevention by treatment with N-butyldeoxynojirimycin.
    Pelled D; Lloyd-Evans E; Riebeling C; Jeyakumar M; Platt FM; Futerman AH
    J Biol Chem; 2003 Aug; 278(32):29496-501. PubMed ID: 12756243
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
    Winton MJ; Lee EB; Sun E; Wong MM; Leight S; Zhang B; Trojanowski JQ; Lee VM
    J Neurosci; 2011 May; 31(21):7691-9. PubMed ID: 21613482
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease.
    Chen Y; Jian J; Hettinghouse A; Zhao X; Setchell KDR; Sun Y; Liu CJ
    J Mol Med (Berl); 2018 Dec; 96(12):1359-1373. PubMed ID: 30341570
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.
    Grimm MO; Zinser EG; Grösgen S; Hundsdörfer B; Rothhaar TL; Burg VK; Kaestner L; Bayer TA; Lipp P; Müller U; Grimm HS; Hartmann T
    PLoS One; 2012; 7(3):e34095. PubMed ID: 22470521
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Plasmid-based gene transfer ameliorates visceral storage in a mouse model of Sandhoff disease.
    Yamaguchi A; Katsuyama K; Suzuki K; Kosaka K; Aoki I; Yamanaka S
    J Mol Med (Berl); 2003 Mar; 81(3):185-93. PubMed ID: 12682727
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.