BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 22498647)

  • 41. High-throughput cytochrome p450 inhibition assays by ultrafast gradient liquid chromatography with tandem mass spectrometry using monolithic columns.
    Peng SX; Barbone AG; Ritchie DM
    Rapid Commun Mass Spectrom; 2003; 17(6):509-18. PubMed ID: 12621611
    [TBL] [Abstract][Full Text] [Related]  

  • 42. HPLC-high-resolution mass spectrometry with polarity switching for increasing throughput of human in vitro cocktail drug-drug interaction assay.
    Ramanathan R; Ghosal A; Ramanathan L; Comstock K; Shen H; Ramanathan D
    Bioanalysis; 2018 May; 10(9):659-671. PubMed ID: 29749249
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Rapid determination of six metabolites from multiple cytochrome P450 probe substrates in human liver microsome by liquid chromatography/mass spectrometry: application to high-throughput inhibition screening of terpenoids.
    He F; Bi HC; Xie ZY; Zuo Z; Li JK; Li X; Zhao LZ; Chen X; Huang M
    Rapid Commun Mass Spectrom; 2007; 21(5):635-43. PubMed ID: 17279482
    [TBL] [Abstract][Full Text] [Related]  

  • 44. In vitro and in vivo assessment of the effect of dalcetrapib on a panel of CYP substrates.
    Derks M; Fowler S; Kuhlmann O
    Curr Med Res Opin; 2009 Apr; 25(4):891-902. PubMed ID: 19245299
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Validated assays for human cytochrome P450 activities.
    Walsky RL; Obach RS
    Drug Metab Dispos; 2004 Jun; 32(6):647-60. PubMed ID: 15155557
    [TBL] [Abstract][Full Text] [Related]  

  • 46. An improved substrate cocktail for assessing direct inhibition and time-dependent inhibition of multiple cytochrome P450s.
    Chen ZH; Zhang SX; Long N; Lin LS; Chen T; Zhang FP; Lv XQ; Ye PZ; Li N; Zhang KZ
    Acta Pharmacol Sin; 2016 May; 37(5):708-18. PubMed ID: 27063220
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.
    Mössner LD; Schmitz A; Theurillat R; Thormann W; Mevissen M
    Am J Vet Res; 2011 Nov; 72(11):1505-13. PubMed ID: 22023129
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Characterisation of cytochrome P450 isoenzyme activity in sheep liver and placental microsomes.
    Meakin AS; Amirmostofian M; Darby JR; Holman SL; Morrison JL; Wiese MD
    Placenta; 2023 Jan; 131():82-89. PubMed ID: 36527743
    [TBL] [Abstract][Full Text] [Related]  

  • 49. A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probe drugs and their corresponding metabolites in human serum and urine.
    Puris E; Pasanen M; Gynther M; Häkkinen MR; Pihlajamäki J; Keränen T; Honkakoski P; Raunio H; Petsalo A
    Anal Bioanal Chem; 2017 Jan; 409(1):251-268. PubMed ID: 27734142
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [TBL] [Abstract][Full Text] [Related]  

  • 51. A cocktail approach for assessing the in vitro activity of human cytochrome P450s: an overview of current methodologies.
    Spaggiari D; Geiser L; Daali Y; Rudaz S
    J Pharm Biomed Anal; 2014 Dec; 101():221-37. PubMed ID: 24746851
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Simultaneous evaluation of substrate-dependent CYP3A inhibition using a CYP3A probe substrates cocktail.
    Lee E; Shon JC; Liu KH
    Biopharm Drug Dispos; 2016 Sep; 37(6):366-72. PubMed ID: 27323294
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Development and validation of a sensitive and specific LC-MS/MS cocktail assay for CYP450 enzymes: Application to study the effect of catechin on rat hepatic CYP activity.
    Nguyen V; Espiritu M; Elbarbry F
    Biomed Chromatogr; 2020 Mar; 34(3):e4789. PubMed ID: 31885091
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Validated method for rapid inhibition screening of six cytochrome P450 enzymes by liquid chromatography-tandem mass spectrometry.
    Li X; Chen X; Li Q; Wang L; Zhong D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jun; 852(1-2):128-37. PubMed ID: 17267297
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Development and validation of a liquid-chromatography high-resolution tandem mass spectrometry approach for quantification of nine cytochrome P450 (CYP) model substrate metabolites in an in vitro CYP inhibition cocktail.
    Dinger J; Meyer MR; Maurer HH
    Anal Bioanal Chem; 2014 Jul; 406(18):4453-64. PubMed ID: 24830396
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP; Otten JN; Hingorani GP; Hartley DP; Franklin RB
    J Pharmacol Toxicol Methods; 2011; 63(3):223-6. PubMed ID: 21111054
    [TBL] [Abstract][Full Text] [Related]  

  • 57. The potential for CYP2D6 inhibition screening using a novel scintillation proximity assay-based approach.
    Delaporte E; Slaughter DE; Egan MA; Gatto GJ; Santos A; Shelley J; Price E; Howells L; Dean DC; Rodrigues AD
    J Biomol Screen; 2001 Aug; 6(4):225-31. PubMed ID: 11689122
    [TBL] [Abstract][Full Text] [Related]  

  • 58. [The in vitro inhibition and induction of cytochrome P450 activities by bentysrepinine: a novel candidate of anti-hepatitis B virus drug].
    Fan HR; Ci XY; Li W; Dong SQ; Zeng Y; Yi XL; Si DY; Liu CX
    Yao Xue Xue Bao; 2016 Dec; 51(12):1864-70. PubMed ID: 29908557
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes.
    Kim JH; Kwon SS; Jeong HU; Lee HS
    Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28468305
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Strategies to in vitro assessment of major human CYP enzyme activities by using liquid chromatography tandem mass spectrometry.
    Lahoz A; Donato MT; Castell JV; Gómez-Lechón MJ
    Curr Drug Metab; 2008 Jan; 9(1):12-9. PubMed ID: 18220567
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.