300 related articles for article (PubMed ID: 22504320)
1. Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease.
Qosa H; Abuznait AH; Hill RA; Kaddoumi A
J Alzheimers Dis; 2012; 31(1):151-65. PubMed ID: 22504320
[TBL] [Abstract][Full Text] [Related]
2. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.
Storck SE; Hartz AMS; Bernard J; Wolf A; Kachlmeier A; Mahringer A; Weggen S; Pahnke J; Pietrzik CU
Brain Behav Immun; 2018 Oct; 73():21-33. PubMed ID: 30041013
[TBL] [Abstract][Full Text] [Related]
3. Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.
Qosa H; Abuasal BS; Romero IA; Weksler B; Couraud PO; Keller JN; Kaddoumi A
Neuropharmacology; 2014 Apr; 79():668-78. PubMed ID: 24467845
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
Shackleton B; Crawford F; Bachmeier C
Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
[TBL] [Abstract][Full Text] [Related]
5. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
[TBL] [Abstract][Full Text] [Related]
6. 1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport.
Guo YX; He LY; Zhang M; Wang F; Liu F; Peng WX
Neuroscience; 2016 May; 322():28-38. PubMed ID: 26820600
[TBL] [Abstract][Full Text] [Related]
7. Olive-oil-derived oleocanthal enhances β-amyloid clearance as a potential neuroprotective mechanism against Alzheimer's disease: in vitro and in vivo studies.
Abuznait AH; Qosa H; Busnena BA; El Sayed KA; Kaddoumi A
ACS Chem Neurosci; 2013 Jun; 4(6):973-82. PubMed ID: 23414128
[TBL] [Abstract][Full Text] [Related]
8. The role of LRP1 in Aβ efflux transport across the blood-brain barrier and cognitive dysfunction in diabetes mellitus.
P X; Zz L; Gg J; Lp W; Cm B; Yl W; Chen MF; W L
Neurochem Int; 2022 Nov; 160():105417. PubMed ID: 36067928
[TBL] [Abstract][Full Text] [Related]
9. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.
Kanekiyo T; Liu CC; Shinohara M; Li J; Bu G
J Neurosci; 2012 Nov; 32(46):16458-65. PubMed ID: 23152628
[TBL] [Abstract][Full Text] [Related]
10. Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease.
Abuznait AH; Cain C; Ingram D; Burk D; Kaddoumi A
J Pharm Pharmacol; 2011 Aug; 63(8):1111-8. PubMed ID: 21718295
[TBL] [Abstract][Full Text] [Related]
11. Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.
Singh I; Sagare AP; Coma M; Perlmutter D; Gelein R; Bell RD; Deane RJ; Zhong E; Parisi M; Ciszewski J; Kasper RT; Deane R
Proc Natl Acad Sci U S A; 2013 Sep; 110(36):14771-6. PubMed ID: 23959870
[TBL] [Abstract][Full Text] [Related]
12. Age-Dependent Regulation of the Blood-Brain Barrier Influx/Efflux Equilibrium of Amyloid-β Peptide in a Mouse Model of Alzheimer's Disease (3xTg-AD).
Do TM; Dodacki A; Alata W; Calon F; Nicolic S; Scherrmann JM; Farinotti R; Bourasset F
J Alzheimers Dis; 2016; 49(2):287-300. PubMed ID: 26484906
[TBL] [Abstract][Full Text] [Related]
13. ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier.
Do TM; Noel-Hudson MS; Ribes S; Besengez C; Smirnova M; Cisternino S; Buyse M; Calon F; Chimini G; Chacun H; Scherrmann JM; Farinotti R; Bourasset F
J Alzheimers Dis; 2012; 30(1):155-66. PubMed ID: 22391220
[TBL] [Abstract][Full Text] [Related]
14. Amylin Enhances Amyloid-β Peptide Brain to Blood Efflux Across the Blood-Brain Barrier.
Mohamed LA; Zhu H; Mousa YM; Wang E; Qiu WQ; Kaddoumi A
J Alzheimers Dis; 2017; 56(3):1087-1099. PubMed ID: 28059785
[TBL] [Abstract][Full Text] [Related]
15. Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.
Kanekiyo T; Zhang J; Liu Q; Liu CC; Zhang L; Bu G
J Neurosci; 2011 Feb; 31(5):1644-51. PubMed ID: 21289173
[TBL] [Abstract][Full Text] [Related]
16. Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.
Storck SE; Meister S; Nahrath J; Meißner JN; Schubert N; Di Spiezio A; Baches S; Vandenbroucke RE; Bouter Y; Prikulis I; Korth C; Weggen S; Heimann A; Schwaninger M; Bayer TA; Pietrzik CU
J Clin Invest; 2016 Jan; 126(1):123-36. PubMed ID: 26619118
[TBL] [Abstract][Full Text] [Related]
17. Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.
Liu CC; Hu J; Zhao N; Wang J; Wang N; Cirrito JR; Kanekiyo T; Holtzman DM; Bu G
J Neurosci; 2017 Apr; 37(15):4023-4031. PubMed ID: 28275161
[TBL] [Abstract][Full Text] [Related]
18. Role of the cannabinoid system in the transit of beta-amyloid across the blood-brain barrier.
Bachmeier C; Beaulieu-Abdelahad D; Mullan M; Paris D
Mol Cell Neurosci; 2013 Sep; 56():255-62. PubMed ID: 23831388
[TBL] [Abstract][Full Text] [Related]
19. Neuronal clearance of amyloid-β by endocytic receptor LRP1.
Kanekiyo T; Cirrito JR; Liu CC; Shinohara M; Li J; Schuler DR; Shinohara M; Holtzman DM; Bu G
J Neurosci; 2013 Dec; 33(49):19276-83. PubMed ID: 24305823
[TBL] [Abstract][Full Text] [Related]
20. LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier.
Pflanzner T; Janko MC; André-Dohmen B; Reuss S; Weggen S; Roebroek AJ; Kuhlmann CR; Pietrzik CU
Neurobiol Aging; 2011 Dec; 32(12):2323.e1-11. PubMed ID: 20630619
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
