BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 22505453)

  • 1. Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.
    Nacerddine K; Beaudry JB; Ginjala V; Westerman B; Mattiroli F; Song JY; van der Poel H; Ponz OB; Pritchard C; Cornelissen-Steijger P; Zevenhoven J; Tanger E; Sixma TK; Ganesan S; van Lohuizen M
    J Clin Invest; 2012 May; 122(5):1920-32. PubMed ID: 22505453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Essential role for activation of the Polycomb group (PcG) protein chromatin silencing pathway in metastatic prostate cancer.
    Berezovska OP; Glinskii AB; Yang Z; Li XM; Hoffman RM; Glinsky GV
    Cell Cycle; 2006 Aug; 5(16):1886-901. PubMed ID: 16963837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PTEN inhibits BMI1 function independently of its phosphatase activity.
    Fan C; He L; Kapoor A; Rybak AP; De Melo J; Cutz JC; Tang D
    Mol Cancer; 2009 Nov; 8():98. PubMed ID: 19903340
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair.
    Ginjala V; Nacerddine K; Kulkarni A; Oza J; Hill SJ; Yao M; Citterio E; van Lohuizen M; Ganesan S
    Mol Cell Biol; 2011 May; 31(10):1972-82. PubMed ID: 21383063
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair.
    Ismail IH; Andrin C; McDonald D; Hendzel MJ
    J Cell Biol; 2010 Oct; 191(1):45-60. PubMed ID: 20921134
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Monoubiquitination of H2AX protein regulates DNA damage response signaling.
    Pan MR; Peng G; Hung WC; Lin SY
    J Biol Chem; 2011 Aug; 286(32):28599-607. PubMed ID: 21676867
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RUNX2 overexpression and PTEN haploinsufficiency cooperate to promote CXCR7 expression and cellular trafficking, AKT hyperactivation and prostate tumorigenesis.
    Bai Y; Yang Y; Yan Y; Zhong J; Blee AM; Pan Y; Ma T; Karnes RJ; Jimenez R; Xu W; Huang H
    Theranostics; 2019; 9(12):3459-3475. PubMed ID: 31281490
    [No Abstract]   [Full Text] [Related]  

  • 8. Akt phosphorylates the transcriptional repressor bmi1 to block its effects on the tumor-suppressing ink4a-arf locus.
    Liu Y; Liu F; Yu H; Zhao X; Sashida G; Deblasio A; Harr M; She QB; Chen Z; Lin HK; Di Giandomenico S; Elf SE; Yang Y; Miyata Y; Huang G; Menendez S; Mellinghoff IK; Rosen N; Pandolfi PP; Hedvat CV; Nimer SD
    Sci Signal; 2012 Oct; 5(247):ra77. PubMed ID: 23092893
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma.
    Adisetiyo H; Liang M; Liao CP; Aycock-Williams A; Cohen MB; Xu S; Neamati N; Conway EM; Cheng CY; Nikitin AY; Roy-Burman P
    PLoS One; 2013; 8(7):e69484. PubMed ID: 23936028
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features.
    van Leenders GJ; Dukers D; Hessels D; van den Kieboom SW; Hulsbergen CA; Witjes JA; Otte AP; Meijer CJ; Raaphorst FM
    Eur Urol; 2007 Aug; 52(2):455-63. PubMed ID: 17134822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The E3 ubiquitin-ligase Bmi1/Ring1A controls the proteasomal degradation of Top2alpha cleavage complex - a potentially new drug target.
    Alchanati I; Teicher C; Cohen G; Shemesh V; Barr HM; Nakache P; Ben-Avraham D; Idelevich A; Angel I; Livnah N; Tuvia S; Reiss Y; Taglicht D; Erez O
    PLoS One; 2009 Dec; 4(12):e8104. PubMed ID: 19956605
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis.
    Jefferies MT; Cox AC; Shorning BY; Meniel V; Griffiths D; Kynaston HG; Smalley MJ; Clarke AR
    J Pathol; 2017 Dec; 243(4):442-456. PubMed ID: 29134654
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.
    Bruggeman SW; Hulsman D; Tanger E; Buckle T; Blom M; Zevenhoven J; van Tellingen O; van Lohuizen M
    Cancer Cell; 2007 Oct; 12(4):328-41. PubMed ID: 17936558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery.
    Facchino S; Abdouh M; Chatoo W; Bernier G
    J Neurosci; 2010 Jul; 30(30):10096-111. PubMed ID: 20668194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperation between FGF8b overexpression and PTEN deficiency in prostate tumorigenesis.
    Zhong C; Saribekyan G; Liao CP; Cohen MB; Roy-Burman P
    Cancer Res; 2006 Feb; 66(4):2188-94. PubMed ID: 16489020
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein.
    Geng C; Kaochar S; Li M; Rajapakshe K; Fiskus W; Dong J; Foley C; Dong B; Zhang L; Kwon OJ; Shah SS; Bolaki M; Xin L; Ittmann M; O'Malley BW; Coarfa C; Mitsiades N
    Oncogene; 2017 Aug; 36(33):4767-4777. PubMed ID: 28414305
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way.
    Zhang X; Wang D; Liu B; Jin X; Wang X; Pan J; Tu W; Shao Y
    J Exp Clin Cancer Res; 2020 Sep; 39(1):190. PubMed ID: 32938489
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells.
    Song LB; Li J; Liao WT; Feng Y; Yu CP; Hu LJ; Kong QL; Xu LH; Zhang X; Liu WL; Li MZ; Zhang L; Kang TB; Fu LW; Huang WL; Xia YF; Tsao SW; Li M; Band V; Band H; Shi QH; Zeng YX; Zeng MS
    J Clin Invest; 2009 Dec; 119(12):3626-36. PubMed ID: 19884659
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cooperation between Stat3 and Akt signaling leads to prostate tumor development in transgenic mice.
    Blando JM; Carbajal S; Abel E; Beltran L; Conti C; Fischer S; DiGiovanni J
    Neoplasia; 2011 Mar; 13(3):254-65. PubMed ID: 21390188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b.
    Buchwald G; van der Stoop P; Weichenrieder O; Perrakis A; van Lohuizen M; Sixma TK
    EMBO J; 2006 Jun; 25(11):2465-74. PubMed ID: 16710298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.