BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

367 related articles for article (PubMed ID: 22506026)

  • 1. Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK).
    Plötz M; Hossini AM; Gillissen B; Daniel PT; Stockfleth E; Eberle J
    PLoS One; 2012; 7(4):e34549. PubMed ID: 22506026
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH; Wei MC; Weiler S; Flavell RA; Mak TW; Lindsten T; Korsmeyer SJ
    Mol Cell; 2001 Sep; 8(3):705-11. PubMed ID: 11583631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells.
    Plötz M; Gillissen B; Hossini AM; Daniel PT; Eberle J
    Cell Death Differ; 2012 Dec; 19(12):1928-38. PubMed ID: 22705850
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC; Kanai M; Inoue-Yamauchi A; Tu HC; Huang Y; Ren D; Kim H; Takeda S; Reyna DE; Chan PM; Ganesan YT; Liao CP; Gavathiotis E; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2015 Oct; 17(10):1270-81. PubMed ID: 26344567
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H; Wolf J; Schafer B; Moldoveanu T; Chipuk JE; Kuwana T
    J Biol Chem; 2011 Jan; 286(1):491-501. PubMed ID: 21041309
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
    J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C; Anwari K; Ninnis RL; Brouwer J; O'Hely M; Evangelista M; Hinds MG; Czabotar PE; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Dis; 2015 Apr; 6(4):e1735. PubMed ID: 25906158
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
    Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Direct interaction of Bax and Bak proteins with Bcl-2 homology domain 3 (BH3)-only proteins in living cells revealed by fluorescence complementation.
    Vela L; Gonzalo O; Naval J; Marzo I
    J Biol Chem; 2013 Feb; 288(7):4935-46. PubMed ID: 23283967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
    Sheridan C; Delivani P; Cullen SP; Martin SJ
    Mol Cell; 2008 Aug; 31(4):570-585. PubMed ID: 18722181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T; Bouchier-Hayes L; Chipuk JE; Bonzon C; Sullivan BA; Green DR; Newmeyer DD
    Mol Cell; 2005 Feb; 17(4):525-35. PubMed ID: 15721256
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway.
    Gillissen B; Essmann F; Graupner V; Stärck L; Radetzki S; Dörken B; Schulze-Osthoff K; Daniel PT
    EMBO J; 2003 Jul; 22(14):3580-90. PubMed ID: 12853473
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the anti-apoptotic mechanism of Bcl-B.
    Zhai D; Ke N; Zhang H; Ladror U; Joseph M; Eichinger A; Godzik A; Ng SC; Reed JC
    Biochem J; 2003 Nov; 376(Pt 1):229-36. PubMed ID: 12921534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. AICAR induces Bax/Bak-dependent apoptosis through upregulation of the BH3-only proteins Bim and Noxa in mouse embryonic fibroblasts.
    González-Gironès DM; Moncunill-Massaguer C; Iglesias-Serret D; Cosialls AM; Pérez-Perarnau A; Palmeri CM; Rubio-Patiño C; Villunger A; Pons G; Gil J
    Apoptosis; 2013 Aug; 18(8):1008-16. PubMed ID: 23605481
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.
    Nakajima W; Tanaka N
    J Nippon Med Sch; 2007 Apr; 74(2):148-57. PubMed ID: 17507791
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BCL-2 proteins and apoptosis: Recent insights and unknowns.
    Edlich F
    Biochem Biophys Res Commun; 2018 May; 500(1):26-34. PubMed ID: 28676391
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.