BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

423 related articles for article (PubMed ID: 22508511)

  • 1. 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
    Martínez P; Flores JM; Blasco MA
    J Cell Biol; 2012 Apr; 197(2):283-300. PubMed ID: 22508511
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Removal of shelterin reveals the telomere end-protection problem.
    Sfeir A; de Lange T
    Science; 2012 May; 336(6081):593-7. PubMed ID: 22556254
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple roles for MRE11 at uncapped telomeres.
    Deng Y; Guo X; Ferguson DO; Chang S
    Nature; 2009 Aug; 460(7257):914-8. PubMed ID: 19633651
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
    Celli GB; de Lange T
    Nat Cell Biol; 2005 Jul; 7(7):712-8. PubMed ID: 15968270
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2.
    Dimitrova N; de Lange T
    Mol Cell Biol; 2009 Oct; 29(20):5552-63. PubMed ID: 19667071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
    Rybanska-Spaeder I; Ghosh R; Franco S
    PLoS One; 2014; 9(9):e108731. PubMed ID: 25264618
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
    Denchi EL; de Lange T
    Nature; 2007 Aug; 448(7157):1068-71. PubMed ID: 17687332
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA-damage response and repair activities at uncapped telomeres depend on RNF8.
    Peuscher MH; Jacobs JJ
    Nat Cell Biol; 2011 Aug; 13(9):1139-45. PubMed ID: 21857671
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of 53BP1 oligomerization in regulating double-strand break repair.
    Lottersberger F; Bothmer A; Robbiani DF; Nussenzweig MC; de Lange T
    Proc Natl Acad Sci U S A; 2013 Feb; 110(6):2146-51. PubMed ID: 23345425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.
    Shibata A; Barton O; Noon AT; Dahm K; Deckbar D; Goodarzi AA; Löbrich M; Jeggo PA
    Mol Cell Biol; 2010 Jul; 30(13):3371-83. PubMed ID: 20421415
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.
    Martínez P; Thanasoula M; Muñoz P; Liao C; Tejera A; McNees C; Flores JM; Fernández-Capetillo O; Tarsounas M; Blasco MA
    Genes Dev; 2009 Sep; 23(17):2060-75. PubMed ID: 19679647
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SMCHD1 promotes ATM-dependent DNA damage signaling and repair of uncapped telomeres.
    Vančevska A; Ahmed W; Pfeiffer V; Feretzaki M; Boulton SJ; Lingner J
    EMBO J; 2020 Apr; 39(7):e102668. PubMed ID: 32080884
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
    Dimitrova N; Chen YC; Spector DL; de Lange T
    Nature; 2008 Nov; 456(7221):524-8. PubMed ID: 18931659
    [TBL] [Abstract][Full Text] [Related]  

  • 14. No overt nucleosome eviction at deprotected telomeres.
    Wu P; de Lange T
    Mol Cell Biol; 2008 Sep; 28(18):5724-35. PubMed ID: 18625717
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line.
    Muraki K; Han L; Miller D; Murnane JP
    PLoS Genet; 2013 Mar; 9(3):e1003386. PubMed ID: 23555296
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development.
    Liu X; Jiang W; Dubois RL; Yamamoto K; Wolner Z; Zha S
    Proc Natl Acad Sci U S A; 2012 Mar; 109(10):3903-8. PubMed ID: 22355127
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair.
    Lam YC; Akhter S; Gu P; Ye J; Poulet A; Giraud-Panis MJ; Bailey SM; Gilson E; Legerski RJ; Chang S
    EMBO J; 2010 Jul; 29(13):2230-41. PubMed ID: 20551906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.
    Guo X; Deng Y; Lin Y; Cosme-Blanco W; Chan S; He H; Yuan G; Brown EJ; Chang S
    EMBO J; 2007 Nov; 26(22):4709-19. PubMed ID: 17948054
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks.
    Kishi S; Zhou XZ; Ziv Y; Khoo C; Hill DE; Shiloh Y; Lu KP
    J Biol Chem; 2001 Aug; 276(31):29282-91. PubMed ID: 11375976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells.
    Kishi S; Lu KP
    J Biol Chem; 2002 Mar; 277(9):7420-9. PubMed ID: 11744712
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.