BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 22509825)

  • 1. Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist.
    Takusagawa S; Yajima K; Miyashita A; Uehara S; Iwatsubo T; Usui T
    Xenobiotica; 2012 Oct; 42(10):957-67. PubMed ID: 22509825
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro inhibition and induction of human cytochrome P450 enzymes by mirabegron, a potent and selective β3-adrenoceptor agonist.
    Takusagawa S; Miyashita A; Iwatsubo T; Usui T
    Xenobiotica; 2012 Dec; 42(12):1187-96. PubMed ID: 22834478
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Absorption, metabolism and excretion of [(14)C]mirabegron (YM178), a potent and selective β(3)-adrenoceptor agonist, after oral administration to healthy male volunteers.
    Takusagawa S; van Lier JJ; Suzuki K; Nagata M; Meijer J; Krauwinkel W; Schaddelee M; Sekiguchi M; Miyashita A; Iwatsubo T; van Gelderen M; Usui T
    Drug Metab Dispos; 2012 Apr; 40(4):815-24. PubMed ID: 22269146
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of cytochrome p450 isoenzymes 3A and 2D6 in the in vivo metabolism of mirabegron, a β3-adrenoceptor agonist.
    Lee J; Moy S; Meijer J; Krauwinkel W; Sawamoto T; Kerbusch V; Kowalski D; Roy M; Marion A; Takusagawa S; van Gelderen M; Keirns J
    Clin Drug Investig; 2013 Jun; 33(6):429-40. PubMed ID: 23625188
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone.
    Kitamura A; Mizuno Y; Natsui K; Yabuki M; Komuro S; Kanamaru H
    Biopharm Drug Dispos; 2005 Mar; 26(2):59-65. PubMed ID: 15619261
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective inhibition of the cytochrome P450 isoform by hyperoside and its potent inhibition of CYP2D6.
    Song M; Hong M; Lee MY; Jee JG; Lee YM; Bae JS; Jeong TC; Lee S
    Food Chem Toxicol; 2013 Sep; 59():549-53. PubMed ID: 23835282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist.
    Usmani KA; Chen WG; Sadeque AJ
    Drug Metab Dispos; 2012 Apr; 40(4):761-71. PubMed ID: 22266842
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment.
    Konishi K; Minematsu T; Nagasaka Y; Tabata K
    Biopharm Drug Dispos; 2019 May; 40(5-6):176-187. PubMed ID: 30985942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mirabegron, a β₃-adrenoceptor agonist for the potential treatment of urinary frequency, urinary incontinence or urgency associated with overactive bladder.
    Tyagi P; Tyagi V
    IDrugs; 2010 Oct; 13(10):713-22. PubMed ID: 20878594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies on the cytochrome P450 (CYP)-mediated metabolic properties of miocamycin: evaluation of the possibility of a metabolic intermediate complex formation with CYP, and identification of the human CYP isoforms.
    Kasahara M; Suzuki H; Komiya I
    Drug Metab Dispos; 2000 Apr; 28(4):409-17. PubMed ID: 10725309
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist.
    Ghosal A; Lu X; Penner N; Gao L; Ramanathan R; Chowdhury SK; Kishnani NS; Alton KB
    Drug Metab Dispos; 2011 Jan; 39(1):30-8. PubMed ID: 20926621
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M; Shindo M; Shimada T
    Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of human cytochrome P-450 isoforms involved in metabolism of R(+)- and S(-)-gallopamil: utility of in vitro disappearance rate.
    Suzuki A; Iida I; Tanaka F; Akimoto M; Fukushima K; Tani M; Ishizaki T; Chiba K
    Drug Metab Dispos; 1999 Nov; 27(11):1254-9. PubMed ID: 10534309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of metabolites and human P450 isoforms involved in the microsomal metabolism of mesaconitine.
    Ye L; Tang L; Gong Y; Lv C; Zheng Z; Jiang Z; Liu Z
    Xenobiotica; 2011 Jan; 41(1):46-58. PubMed ID: 21105783
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW; Dean DC; Miller RR; Rasmusson GH; Chiu SH
    Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of human liver cytochrome P450 enzymes involved in the metabolism of a new H+/K+-ATPase inhibitor KR-60436.
    Ji HY; Lee HW; Kim HH; Choi JK; Lee HS
    Toxicol Lett; 2005 Jan; 155(1):103-14. PubMed ID: 15585365
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator.
    Jornil J; Jensen KG; Larsen F; Linnet K
    Drug Metab Dispos; 2010 Mar; 38(3):376-85. PubMed ID: 20007670
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.