243 related articles for article (PubMed ID: 22509942)
1. Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity.
Huang FC; Chang CC; Wang JM; Chang TC; Lin JJ
Br J Pharmacol; 2012 Sep; 167(2):393-406. PubMed ID: 22509942
[TBL] [Abstract][Full Text] [Related]
2. G-quadruplex stabilizer 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells.
Huang FC; Chang CC; Lou PJ; Kuo IC; Chien CW; Chen CT; Shieh FY; Chang TC; Lin JJ
Mol Cancer Res; 2008 Jun; 6(6):955-64. PubMed ID: 18515756
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers.
Wang JM; Huang FC; Kuo MH; Wang ZF; Tseng TY; Chang LC; Yen SJ; Chang TC; Lin JJ
J Biol Chem; 2014 May; 289(21):14612-23. PubMed ID: 24713700
[TBL] [Abstract][Full Text] [Related]
4. G-quadruplex stabilizer Tetra-Pt(bpy) disrupts telomere maintenance and impairs FAK-mediated migration of telomerase-positive cells.
Shen Z; Zheng R; Yang H; Xing S; Jin X; Yan H; Zhu J; Mei Y; Lin F; Zheng X
Int J Biol Macromol; 2022 Jul; 213():858-870. PubMed ID: 35697164
[TBL] [Abstract][Full Text] [Related]
5. Interaction between human telomere and a carbazole derivative: a molecular dynamics simulation of a quadruplex stabilizer and telomerase inhibitor.
Yang DY; Chang TC; Sheu SY
J Phys Chem A; 2007 Sep; 111(38):9224-32. PubMed ID: 17630723
[TBL] [Abstract][Full Text] [Related]
6. A G-quadruplex-interactive potent small-molecule inhibitor of telomerase exhibiting in vitro and in vivo antitumor activity.
Gowan SM; Harrison JR; Patterson L; Valenti M; Read MA; Neidle S; Kelland LR
Mol Pharmacol; 2002 May; 61(5):1154-62. PubMed ID: 11961134
[TBL] [Abstract][Full Text] [Related]
7. Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands.
Chen CY; Wang Q; Liu JQ; Hao YH; Tan Z
J Am Chem Soc; 2011 Sep; 133(38):15036-44. PubMed ID: 21846102
[TBL] [Abstract][Full Text] [Related]
8. c-Myc quadruplex-forming sequence Pu-27 induces extensive damage in both telomeric and nontelomeric regions of DNA.
Islam MA; Thomas SD; Murty VV; Sedoris KJ; Miller DM
J Biol Chem; 2014 Mar; 289(12):8521-31. PubMed ID: 24464582
[TBL] [Abstract][Full Text] [Related]
9. G-Quadruplex DNA as a target for drug design.
Kerwin SM
Curr Pharm Des; 2000 Mar; 6(4):441-78. PubMed ID: 10788591
[TBL] [Abstract][Full Text] [Related]
10. Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase.
Gomez D; Aouali N; Renaud A; Douarre C; Shin-Ya K; Tazi J; Martinez S; Trentesaux C; Morjani H; Riou JF
Cancer Res; 2003 Oct; 63(19):6149-53. PubMed ID: 14559794
[TBL] [Abstract][Full Text] [Related]
11. Targeting pancreatic cancer with a G-quadruplex ligand.
Gunaratnam M; de la Fuente M; Hampel SM; Todd AK; Reszka AP; Schätzlein A; Neidle S
Bioorg Med Chem; 2011 Dec; 19(23):7151-7. PubMed ID: 22041170
[TBL] [Abstract][Full Text] [Related]
12. G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells.
Amato R; Valenzuela M; Berardinelli F; Salvati E; Maresca C; Leone S; Antoccia A; Sgura A
Genes (Basel); 2020 Mar; 11(3):. PubMed ID: 32183119
[TBL] [Abstract][Full Text] [Related]
13. The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.
Burger AM; Dai F; Schultes CM; Reszka AP; Moore MJ; Double JA; Neidle S
Cancer Res; 2005 Feb; 65(4):1489-96. PubMed ID: 15735037
[TBL] [Abstract][Full Text] [Related]
14. Trisubstituted acridines as G-quadruplex telomere targeting agents. Effects of extensions of the 3,6- and 9-side chains on quadruplex binding, telomerase activity, and cell proliferation.
Moore MJ; Schultes CM; Cuesta J; Cuenca F; Gunaratnam M; Tanious FA; Wilson WD; Neidle S
J Med Chem; 2006 Jan; 49(2):582-99. PubMed ID: 16420044
[TBL] [Abstract][Full Text] [Related]
15. Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells.
Zhou G; Liu X; Li Y; Xu S; Ma C; Wu X; Cheng Y; Yu Z; Zhao G; Chen Y
Oncotarget; 2016 Mar; 7(12):14925-39. PubMed ID: 26908447
[TBL] [Abstract][Full Text] [Related]
16. Discovery of Novel Schizocommunin Derivatives as Telomeric G-Quadruplex Ligands That Trigger Telomere Dysfunction and the Deoxyribonucleic Acid (DNA) Damage Response.
Che T; Chen SB; Tu JL; Wang B; Wang YQ; Zhang Y; Wang J; Wang ZQ; Zhang ZP; Ou TM; Zhao Y; Tan JH; Huang ZS
J Med Chem; 2018 Apr; 61(8):3436-3453. PubMed ID: 29618208
[TBL] [Abstract][Full Text] [Related]
17. Stabilization of Telomere G-Quadruplexes Interferes with Human Herpesvirus 6A Chromosomal Integration.
Gilbert-Girard S; Gravel A; Artusi S; Richter SN; Wallaschek N; Kaufer BB; Flamand L
J Virol; 2017 Jul; 91(14):. PubMed ID: 28468887
[TBL] [Abstract][Full Text] [Related]
18. Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes.
Gowan SM; Heald R; Stevens MF; Kelland LR
Mol Pharmacol; 2001 Nov; 60(5):981-8. PubMed ID: 11641426
[TBL] [Abstract][Full Text] [Related]
19. Design and synthesis of new benzimidazole-carbazole conjugates for the stabilization of human telomeric DNA, telomerase inhibition, and their selective action on cancer cells.
Maji B; Kumar K; Kaulage M; Muniyappa K; Bhattacharya S
J Med Chem; 2014 Aug; 57(16):6973-88. PubMed ID: 25062468
[TBL] [Abstract][Full Text] [Related]
20. Methods of studying telomere damage induced by quadruplex-ligand complexes.
Rizzo A; Salvati E; Biroccio A
Methods; 2012 May; 57(1):93-9. PubMed ID: 22410593
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]