BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 22513363)

  • 1. Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells.
    Ridgway LD; Wetzel MD; Ngo JA; Erdreich-Epstein A; Marchetti D
    Mol Cancer Res; 2012 Jun; 10(6):689-702. PubMed ID: 22513363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of GEF-H1 induced signaling by heparanase in brain metastatic melanoma cells.
    Ridgway LD; Wetzel MD; Marchetti D
    J Cell Biochem; 2010 Dec; 111(5):1299-309. PubMed ID: 20803552
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epidermal growth factor-induced heparanase nucleolar localization augments DNA topoisomerase I activity in brain metastatic breast cancer.
    Zhang L; Sullivan P; Suyama J; Marchetti D
    Mol Cancer Res; 2010 Feb; 8(2):278-90. PubMed ID: 20164500
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Guanine nucleotide exchange factor-H1 regulates cell migration via localized activation of RhoA at the leading edge.
    Nalbant P; Chang YC; Birkenfeld J; Chang ZF; Bokoch GM
    Mol Biol Cell; 2009 Sep; 20(18):4070-82. PubMed ID: 19625450
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling.
    Liao YC; Ruan JW; Lua I; Li MH; Chen WL; Wang JR; Kao RH; Chen JH
    Oncogene; 2012 Jun; 31(25):3086-97. PubMed ID: 22002306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer.
    Zhang L; Ngo JA; Wetzel MD; Marchetti D
    Neoplasia; 2015 Jan; 17(1):101-13. PubMed ID: 25622903
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase.
    Zhang L; Sullivan PS; Goodman JC; Gunaratne PH; Marchetti D
    Cancer Res; 2011 Feb; 71(3):645-54. PubMed ID: 21266359
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Guanine nucleotide exchange factor-H1 signaling is involved in lipopolysaccharide-induced endothelial barrier dysfunction.
    Zhou Z; Guo F; Dou Y; Tang J; Huan J
    Surgery; 2013 Sep; 154(3):621-31. PubMed ID: 23859306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. GEF-H1-RhoA signaling pathway mediates LPS-induced NF-κB transactivation and IL-8 synthesis in endothelial cells.
    Guo F; Tang J; Zhou Z; Dou Y; Van Lonkhuyzen D; Gao C; Huan J
    Mol Immunol; 2012 Feb; 50(1-2):98-107. PubMed ID: 22226472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase.
    McSherry EA; Brennan K; Hudson L; Hill AD; Hopkins AM
    Breast Cancer Res; 2011 Mar; 13(2):R31. PubMed ID: 21429211
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells.
    Eitaki M; Yamamori T; Meike S; Yasui H; Inanami O
    BMC Cancer; 2012 Oct; 12():469. PubMed ID: 23057787
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization.
    Yamahashi Y; Saito Y; Murata-Kamiya N; Hatakeyama M
    J Biol Chem; 2011 Dec; 286(52):44576-84. PubMed ID: 22072711
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heparanase Modulates Shh and Wnt3a Signaling in Human Medulloblastoma Cells.
    Ridgway LD; Wetzel MD; Marchetti D
    Exp Ther Med; 2011 Mar; 2(2):229-238. PubMed ID: 21442027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases.
    Ren Y; Li R; Zheng Y; Busch H
    J Biol Chem; 1998 Dec; 273(52):34954-60. PubMed ID: 9857026
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heparanase-1-induced shedding of heparan sulfate from syndecan-1 in hepatocarcinoma cell facilitates lymphatic endothelial cell proliferation via VEGF-C/ERK pathway.
    Yu S; Lv H; Zhang H; Jiang Y; Hong Y; Xia R; Zhang Q; Ju W; Jiang L; Ou G; Zhang J; Wang S; Zhang J
    Biochem Biophys Res Commun; 2017 Apr; 485(2):432-439. PubMed ID: 28209511
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration.
    Tsapara A; Luthert P; Greenwood J; Hill CS; Matter K; Balda MS
    Mol Biol Cell; 2010 Mar; 21(6):860-70. PubMed ID: 20089843
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.
    Waheed F; Dan Q; Amoozadeh Y; Zhang Y; Tanimura S; Speight P; Kapus A; Szászi K
    Mol Biol Cell; 2013 Apr; 24(7):1068-82. PubMed ID: 23389627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction.
    Birukova AA; Adyshev D; Gorshkov B; Bokoch GM; Birukov KG; Verin AD
    Am J Physiol Lung Cell Mol Physiol; 2006 Mar; 290(3):L540-8. PubMed ID: 16257999
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1.
    Murakami M; Meneses PI; Knight JS; Lan K; Kaul R; Verma SC; Robertson ES
    Int J Cancer; 2008 Aug; 123(3):500-10. PubMed ID: 18470881
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P; Huynh-Do U
    Cell Signal; 2014 Mar; 26(3):483-91. PubMed ID: 24308970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.