106 related articles for article (PubMed ID: 22516260)
1. DNA damage response and inflammatory signaling limit the MLL-ENL-induced leukemogenesis in vivo.
Takacova S; Slany R; Bartkova J; Stranecky V; Dolezel P; Luzna P; Bartek J; Divoky V
Cancer Cell; 2012 Apr; 21(4):517-31. PubMed ID: 22516260
[TBL] [Abstract][Full Text] [Related]
2. MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation.
Schreiner S; Birke M; García-Cuéllar MP; Zilles O; Greil J; Slany RK
Cancer Res; 2001 Sep; 61(17):6480-6. PubMed ID: 11522644
[TBL] [Abstract][Full Text] [Related]
3. MLL-ENL-mediated leukemia initiation at the interface of lymphoid commitment.
Ugale A; Säwén P; Dudenhöffer-Pfeifer M; Wahlestedt M; Norddahl GL; Bryder D
Oncogene; 2017 Jun; 36(22):3207-3212. PubMed ID: 28068328
[TBL] [Abstract][Full Text] [Related]
4. Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.
Zeisig BB; Milne T; García-Cuéllar MP; Schreiner S; Martin ME; Fuchs U; Borkhardt A; Chanda SK; Walker J; Soden R; Hess JL; Slany RK
Mol Cell Biol; 2004 Jan; 24(2):617-28. PubMed ID: 14701735
[TBL] [Abstract][Full Text] [Related]
5. MLL-AF9 leukemia stem cells: hardwired or taking cues from the microenvironment?
Muntean AG; Hess JL
Cancer Cell; 2008 Jun; 13(6):465-7. PubMed ID: 18538728
[TBL] [Abstract][Full Text] [Related]
6. The efficiency of murine MLL-ENL-driven leukemia initiation changes with age and peaks during neonatal development.
Okeyo-Owuor T; Li Y; Patel RM; Yang W; Casey EB; Cluster AS; Porter SN; Bryder D; Magee JA
Blood Adv; 2019 Aug; 3(15):2388-2399. PubMed ID: 31405949
[TBL] [Abstract][Full Text] [Related]
7. Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.
Horton SJ; Walf-Vorderwülbecke V; Chatters SJ; Sebire NJ; de Boer J; Williams O
Blood; 2009 May; 113(20):4922-9. PubMed ID: 19029444
[TBL] [Abstract][Full Text] [Related]
8. Tet1 is not required for myeloid leukemogenesis by MLL-ENL in novel mouse models.
Ono R; Masuya M; Inoue N; Shinmei M; Ishii S; Maegawa Y; Maharjan BD; Katayama N; Nosaka T
PLoS One; 2021; 16(3):e0248425. PubMed ID: 33705482
[TBL] [Abstract][Full Text] [Related]
9. Transcriptional activation by MLL fusion proteins in leukemogenesis.
Yokoyama A
Exp Hematol; 2017 Feb; 46():21-30. PubMed ID: 27865805
[TBL] [Abstract][Full Text] [Related]
10. Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C.
Schwieger M; Schüler A; Forster M; Engelmann A; Arnold MA; Delwel R; Valk PJ; Löhler J; Slany RK; Olson EN; Stocking C
Blood; 2009 Sep; 114(12):2476-88. PubMed ID: 19584403
[TBL] [Abstract][Full Text] [Related]
11. MLL chimeric protein activation renders cells vulnerable to chromosomal damage: an explanation for the very short latency of infant leukemia.
Eguchi M; Eguchi-Ishimae M; Knight D; Kearney L; Slany R; Greaves M
Genes Chromosomes Cancer; 2006 Aug; 45(8):754-60. PubMed ID: 16688745
[TBL] [Abstract][Full Text] [Related]
12. Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia.
Liu T; Jankovic D; Brault L; Ehret S; Baty F; Stavropoulou V; Rossi V; Biondi A; Schwaller J
Leukemia; 2010 Mar; 24(3):601-12. PubMed ID: 20072157
[TBL] [Abstract][Full Text] [Related]
13. Continuous MLL-ENL expression is necessary to establish a "Hox Code" and maintain immortalization of hematopoietic progenitor cells.
Horton SJ; Grier DG; McGonigle GJ; Thompson A; Morrow M; De Silva I; Moulding DA; Kioussis D; Lappin TR; Brady HJ; Williams O
Cancer Res; 2005 Oct; 65(20):9245-52. PubMed ID: 16230385
[TBL] [Abstract][Full Text] [Related]
14. Clinical outcome and monitoring of minimal residual disease in patients with acute lymphoblastic leukemia expressing the MLL/ENL fusion gene.
Elia L; Grammatico S; Paoloni F; Vignetti M; Rago A; Cenfra N; Mecarocci S; Mancini M; Luciani M; Di Raimondo F; Cazzaniga G; Matarazzo M; Moleti ML; Santoro L; Gaidano G; Foà R; Mandelli F; Cimino G
Am J Hematol; 2011 Dec; 86(12):993-7. PubMed ID: 21953510
[TBL] [Abstract][Full Text] [Related]
15. Multistep pathogenesis of leukemia via the MLL-AF4 chimeric gene/Flt3 gene tyrosine kinase domain (TKD) mutation-related enhancement of S100A6 expression.
Yamaguchi H; Hanawa H; Uchida N; Inamai M; Sawaguchi K; Mitamura Y; Shimada T; Dan K; Inokuchi K
Exp Hematol; 2009 Jun; 37(6):701-14. PubMed ID: 19463771
[TBL] [Abstract][Full Text] [Related]
16. Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation.
Ono R; Kumagai H; Nakajima H; Hishiya A; Taki T; Horikawa K; Takatsu K; Satoh T; Hayashi Y; Kitamura T; Nosaka T
Leukemia; 2009 Dec; 23(12):2197-209. PubMed ID: 19710696
[TBL] [Abstract][Full Text] [Related]
17. Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19ARF.
Nishimoto N; Arai S; Ichikawa M; Nakagawa M; Goyama S; Kumano K; Takahashi T; Kamikubo Y; Imai Y; Kurokawa M
Blood; 2011 Sep; 118(9):2541-50. PubMed ID: 21757616
[TBL] [Abstract][Full Text] [Related]
18. Mixed lineage leukemia: roles in human malignancies and potential therapy.
Marschalek R
FEBS J; 2010 Apr; 277(8):1822-31. PubMed ID: 20236311
[TBL] [Abstract][Full Text] [Related]
19. The oncoprotein MLL-ENL disturbs hematopoietic lineage determination and transforms a biphenotypic lymphoid/myeloid cell.
Zeisig BB; García-Cuéllar MP; Winkler TH; Slany RK
Oncogene; 2003 Mar; 22(11):1629-37. PubMed ID: 12642866
[TBL] [Abstract][Full Text] [Related]
20. The mechanism of hematopoietic progenitor cell immortalization by MLL-ENL.
Horton SJ; Williams O
Cell Cycle; 2006 Feb; 5(4):360-2. PubMed ID: 16479159
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
