BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 22521293)

  • 1. ETS-dependent p16INK4a and p21waf1/cip1 gene expression upon endothelin-1 stimulation in malignant versus and non-malignant proximal tubule cells.
    von Brandenstein M; Schlosser M; Richter C; Depping R; Fries JW
    Life Sci; 2012 Oct; 91(13-14):562-71. PubMed ID: 22521293
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.
    Takeuchi S; Takahashi A; Motoi N; Yoshimoto S; Tajima T; Yamakoshi K; Hirao A; Yanagi S; Fukami K; Ishikawa Y; Sone S; Hara E; Ohtani N
    Cancer Res; 2010 Nov; 70(22):9381-90. PubMed ID: 21062974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. p53 Deficiency leads to compensatory up-regulation of p16INK4a.
    Leong WF; Chau JF; Li B
    Mol Cancer Res; 2009 Mar; 7(3):354-60. PubMed ID: 19240179
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Id1 is down-regulated by hepatocyte growth factor via ERK-dependent and ERK-independent signaling pathways, leading to increased expression of p16INK4a in hepatoma cells.
    Ushio K; Hashimoto T; Kitamura N; Tanaka T
    Mol Cancer Res; 2009 Jul; 7(7):1179-88. PubMed ID: 19567783
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.
    Zheng QH; Ma LW; Zhu WG; Zhang ZY; Tong TJ
    J Cell Biochem; 2006 Aug; 98(5):1230-48. PubMed ID: 16514663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two mechanisms underlying the loss of p16(Ink4a) function are associated with distinct tumorigenic consequences for WS MEFs escaping from senescence.
    Wu X; Jia S; Zhang X; Si X; Tang W; Luo Y
    Mech Ageing Dev; 2012 Aug; 133(8):549-55. PubMed ID: 22813853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells.
    Enomoto K; Mimura T; Harris DL; Joyce NC
    Invest Ophthalmol Vis Sci; 2006 Oct; 47(10):4330-40. PubMed ID: 17003423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The expression of p16INK4a tumor suppressor is upregulated by human cytomegalovirus infection and required for optimal viral replication.
    Zannetti C; Mondini M; De Andrea M; Caposio P; Hara E; Peters G; Gribaudo G; Gariglio M; Landolfo S
    Virology; 2006 May; 349(1):79-86. PubMed ID: 16504234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA; Mehmi I; Atlas E; Colomer R; Lupu R
    Int J Oncol; 2004 Mar; 24(3):591-608. PubMed ID: 14767544
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Up-regulation of cell cycle regulatory genes after renal ischemia/reperfusion: differential expression of p16(INK4a), p21(WAF1/CIP1) and p27(Kip1) cyclin-dependent kinase inhibitor genes depending on reperfusion time.
    Chkhotua AB; Abendroth D; Froeba G; Schelzig H
    Transpl Int; 2006 Jan; 19(1):72-7. PubMed ID: 16359379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence.
    Ohtani N; Zebedee Z; Huot TJ; Stinson JA; Sugimoto M; Ohashi Y; Sharrocks AD; Peters G; Hara E
    Nature; 2001 Feb; 409(6823):1067-70. PubMed ID: 11234019
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of p53, p21WAF1/CIP1, p16INK4A and Ki-67 proteins in serous ovarian tumors.
    Buchynska LG; Nesina IP; Yurchenko NP; Bilyk OO; Grinkevych VN; Svintitsky VS
    Exp Oncol; 2007 Mar; 29(1):49-53. PubMed ID: 17431389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells.
    Park US; Park SK; Lee YI; Park JG; Lee YI
    Oncogene; 2000 Jul; 19(30):3384-94. PubMed ID: 10918595
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hepatitis B virus X protein overcomes stress-induced premature senescence by repressing p16(INK4a) expression via DNA methylation.
    Kim YJ; Jung JK; Lee SY; Jang KL
    Cancer Lett; 2010 Feb; 288(2):226-35. PubMed ID: 19656618
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Effects of extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activation on proliferation and cell cycle associated genes in human colon cancer cells].
    Wang X; Lu R; Fang JY
    Zhonghua Yi Xue Za Zhi; 2007 Apr; 87(14):982-6. PubMed ID: 17650425
    [TBL] [Abstract][Full Text] [Related]  

  • 16. All-trans retinoic acid induces cellular senescence by up-regulating levels of p16 and p21 via promoter hypomethylation.
    Lim JS; Park SH; Jang KL
    Biochem Biophys Res Commun; 2011 Sep; 412(3):500-5. PubMed ID: 21843507
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of p16INK4A promotes cellular senescence of bone marrow-derived mesenchymal stem cells from systemic lupus erythematosus patients.
    Gu Z; Cao X; Jiang J; Li L; Da Z; Liu H; Cheng C
    Cell Signal; 2012 Dec; 24(12):2307-14. PubMed ID: 22820504
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alternative pathway of transcriptional induction of p21WAF1/Cip1 by cyclosporine A in p53-deficient human glioblastoma cells.
    Zupanska A; Adach A; Dziembowska M; Kaminska B
    Cell Signal; 2007 Jun; 19(6):1268-78. PubMed ID: 17321721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transcriptional factor HBP1 targets P16(INK4A), upregulating its expression and consequently is involved in Ras-induced premature senescence.
    Li H; Wang W; Liu X; Paulson KE; Yee AS; Zhang X
    Oncogene; 2010 Sep; 29(36):5083-94. PubMed ID: 20581871
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of cell-cycle mediators in ovarian cancer cells after transfection with p16(INK4a), p21(WAF1/Cip-1), and p53.
    Ramirez PT; Gershenson DM; Tortolero-Luna G; Ramondetta LM; Fightmaster D; Wharton JT; Wolf JK
    Gynecol Oncol; 2001 Dec; 83(3):543-8. PubMed ID: 11733969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.