BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 22532874)

  • 1. pVHL mediates K63-linked ubiquitination of nCLU.
    Xue J; Lv DD; Jiao S; Zhao W; Li X; Sun H; Yan B; Fan L; Hu RG; Fang J
    PLoS One; 2012; 7(4):e35848. PubMed ID: 22532874
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Estrogen receptor α is a novel target of the Von Hippel-Lindau protein and is responsible for the proliferation of VHL-deficient cells under hypoxic conditions.
    Jung YS; Lee SJ; Yoon MH; Ha NC; Park BJ
    Cell Cycle; 2012 Dec; 11(23):4462-73. PubMed ID: 23159849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WSB1 promotes tumor metastasis by inducing pVHL degradation.
    Kim JJ; Lee SB; Jang J; Yi SY; Kim SH; Han SA; Lee JM; Tong SY; Vincelette ND; Gao B; Yin P; Evans D; Choi DW; Qin B; Liu T; Zhang H; Deng M; Jen J; Zhang J; Wang L; Lou Z
    Genes Dev; 2015 Nov; 29(21):2244-57. PubMed ID: 26545811
    [TBL] [Abstract][Full Text] [Related]  

  • 4. USP9X destabilizes pVHL and promotes cell proliferation.
    Zhang C; Peng Z; Zhu M; Wang P; Du X; Li X; Liu Y; Jin Y; McNutt MA; Yin Y
    Oncotarget; 2016 Sep; 7(37):60519-60534. PubMed ID: 27517496
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
    Corn PG; McDonald ER; Herman JG; El-Deiry WS
    Nat Genet; 2003 Nov; 35(3):229-37. PubMed ID: 14556007
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Clusterin is a secreted marker for a hypoxia-inducible factor-independent function of the von Hippel-Lindau tumor suppressor protein.
    Nakamura E; Abreu-e-Lima P; Awakura Y; Inoue T; Kamoto T; Ogawa O; Kotani H; Manabe T; Zhang GJ; Kondo K; Nosé V; Kaelin WG
    Am J Pathol; 2006 Feb; 168(2):574-84. PubMed ID: 16436671
    [TBL] [Abstract][Full Text] [Related]  

  • 7. pVHL mediates K63-linked ubiquitination of IKKβ, leading to IKKβ inactivation.
    Wang Y; Zhao W; Gao Q; Fan L; Qin Y; Zhou H; Li M; Fang J
    Cancer Lett; 2016 Dec; 383(1):1-8. PubMed ID: 27693634
    [TBL] [Abstract][Full Text] [Related]  

  • 8. pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation.
    Chen J; Liu F; Li H; Archacki S; Gao M; Liu Y; Liao S; Huang M; Wang J; Yu S; Li C; Tang Z; Liu M
    Cell Signal; 2015 Nov; 27(11):2314-23. PubMed ID: 26296657
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.
    Cockman ME; Masson N; Mole DR; Jaakkola P; Chang GW; Clifford SC; Maher ER; Pugh CW; Ratcliffe PJ; Maxwell PH
    J Biol Chem; 2000 Aug; 275(33):25733-41. PubMed ID: 10823831
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes.
    Hicks KC; Patel TB
    J Biol Chem; 2016 Aug; 291(32):16787-801. PubMed ID: 27281823
    [TBL] [Abstract][Full Text] [Related]  

  • 11. pVHL's kryptonite: E2-EPF UCP.
    Ohh M
    Cancer Cell; 2006 Aug; 10(2):95-7. PubMed ID: 16904608
    [TBL] [Abstract][Full Text] [Related]  

  • 12. von Hippel-Lindau protein promotes Skp2 destabilization on DNA damage.
    Roe JS; Kim HR; Hwang IY; Cho EJ; Youn HD
    Oncogene; 2011 Jul; 30(28):3127-38. PubMed ID: 21358672
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The von Hippel-Lindau tumor suppressor protein mediates ubiquitination of activated atypical protein kinase C.
    Okuda H; Saitoh K; Hirai S; Iwai K; Takaki Y; Baba M; Minato N; Ohno S; Shuin T
    J Biol Chem; 2001 Nov; 276(47):43611-7. PubMed ID: 11574546
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1.
    Foy RL; Chitalia VC; Panchenko MV; Zeng L; Lopez D; Lee JW; Rana SV; Boletta A; Qian F; Tsiokas L; Piontek KB; Germino GG; Zhou MI; Cohen HT
    Hum Mol Genet; 2012 Dec; 21(26):5456-71. PubMed ID: 23001567
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ubiquitination of a novel deubiquitinating enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein.
    Li Z; Na X; Wang D; Schoen SR; Messing EM; Wu G
    J Biol Chem; 2002 Feb; 277(7):4656-62. PubMed ID: 11739384
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diverse effects of mutations in exon II of the von Hippel-Lindau (VHL) tumor suppressor gene on the interaction of pVHL with the cytosolic chaperonin and pVHL-dependent ubiquitin ligase activity.
    Hansen WJ; Ohh M; Moslehi J; Kondo K; Kaelin WG; Welch WJ
    Mol Cell Biol; 2002 Mar; 22(6):1947-60. PubMed ID: 11865071
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKCzetaII is a target for degradation through the tumour suppressor protein pVHL.
    Iturrioz X; Parker PJ
    FEBS Lett; 2007 Apr; 581(7):1397-402. PubMed ID: 17350623
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor.
    Liu W; Xin H; Eckert DT; Brown JA; Gnarra JR
    Oncogene; 2011 Jan; 30(1):21-31. PubMed ID: 20802534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The von Hippel-Lindau protein pVHL inhibits ribosome biogenesis and protein synthesis.
    Zhao WT; Zhou CF; Li XB; Zhang YF; Fan L; Pelletier J; Fang J
    J Biol Chem; 2013 Jun; 288(23):16588-16597. PubMed ID: 23612971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.
    Miller F; Kentsis A; Osman R; Pan ZQ
    J Biol Chem; 2005 Mar; 280(9):7985-96. PubMed ID: 15611064
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.