176 related articles for article (PubMed ID: 22536782)
1. Bivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative manner.
McDonald CB; Bhat V; Mikles DC; Deegan BJ; Seldeen KL; Farooq A
FEBS J; 2012 Jun; 279(12):2156-73. PubMed ID: 22536782
[TBL] [Abstract][Full Text] [Related]
2. Binding of the cSH3 domain of Grb2 adaptor to two distinct RXXK motifs within Gab1 docker employs differential mechanisms.
McDonald CB; Seldeen KL; Deegan BJ; Bhat V; Farooq A
J Mol Recognit; 2011; 24(4):585-96. PubMed ID: 21472810
[TBL] [Abstract][Full Text] [Related]
3. Allostery mediates ligand binding to Grb2 adaptor in a mutually exclusive manner.
McDonald CB; El Hokayem J; Zafar N; Balke JE; Bhat V; Mikles DC; Deegan BJ; Seldeen KL; Farooq A
J Mol Recognit; 2013 Feb; 26(2):92-103. PubMed ID: 23334917
[TBL] [Abstract][Full Text] [Related]
4. Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.
McDonald CB; Balke JE; Bhat V; Mikles DC; Deegan BJ; Seldeen KL; Farooq A
Biochemistry; 2012 Mar; 51(10):2122-35. PubMed ID: 22360309
[TBL] [Abstract][Full Text] [Related]
5. Assembly of the Sos1-Grb2-Gab1 ternary signaling complex is under allosteric control.
McDonald CB; Seldeen KL; Deegan BJ; Bhat V; Farooq A
Arch Biochem Biophys; 2010 Feb; 494(2):216-25. PubMed ID: 20005866
[TBL] [Abstract][Full Text] [Related]
6. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases.
Lock LS; Royal I; Naujokas MA; Park M
J Biol Chem; 2000 Oct; 275(40):31536-45. PubMed ID: 10913131
[TBL] [Abstract][Full Text] [Related]
7. High-Affinity Interactions of the nSH3/cSH3 Domains of Grb2 with the C-Terminal Proline-Rich Domain of SOS1.
Liao TJ; Jang H; Nussinov R; Fushman D
J Am Chem Soc; 2020 Feb; 142(7):3401-3411. PubMed ID: 31970984
[TBL] [Abstract][Full Text] [Related]
8. Structural basis of the differential binding of the SH3 domains of Grb2 adaptor to the guanine nucleotide exchange factor Sos1.
McDonald CB; Seldeen KL; Deegan BJ; Farooq A
Arch Biochem Biophys; 2008 Nov; 479(1):52-62. PubMed ID: 18778683
[TBL] [Abstract][Full Text] [Related]
9. The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner.
Bongartz H; Gille K; Hessenkemper W; Mandel K; Lewitzky M; Feller SM; Schaper F
Cell Commun Signal; 2019 Oct; 17(1):135. PubMed ID: 31651330
[TBL] [Abstract][Full Text] [Related]
10. Mutant huntingtin replaces Gab1 and interacts with C-terminal SH3 domain of growth factor receptor binding protein 2 (Grb2).
Baksi S; Basu S; Mukhopadhyay D
Neurosci Res; 2014 Oct; 87():77-83. PubMed ID: 25041730
[TBL] [Abstract][Full Text] [Related]
11. SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate manner.
McDonald CB; Seldeen KL; Deegan BJ; Farooq A
Biochemistry; 2009 May; 48(19):4074-85. PubMed ID: 19323566
[TBL] [Abstract][Full Text] [Related]
12. How to Grb2 a Gab.
Wöhrle FU; Daly RJ; Brummer T
Structure; 2009 Jun; 17(6):779-81. PubMed ID: 19523893
[TBL] [Abstract][Full Text] [Related]
13. Sos-mediated activation of rac1 by p66shc.
Khanday FA; Santhanam L; Kasuno K; Yamamori T; Naqvi A; Dericco J; Bugayenko A; Mattagajasingh I; Disanza A; Scita G; Irani K
J Cell Biol; 2006 Mar; 172(6):817-22. PubMed ID: 16520382
[TBL] [Abstract][Full Text] [Related]
14. Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET.
Chaudhuri A; Xie MH; Yang B; Mahapatra K; Liu J; Marsters S; Bodepudi S; Ashkenazi A
J Biol Chem; 2011 Sep; 286(37):32762-74. PubMed ID: 21784853
[TBL] [Abstract][Full Text] [Related]
15. The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.
Lewitzky M; Kardinal C; Gehring NH; Schmidt EK; Konkol B; Eulitz M; Birchmeier W; Schaeper U; Feller SM
Oncogene; 2001 Mar; 20(9):1052-62. PubMed ID: 11314042
[TBL] [Abstract][Full Text] [Related]
16. SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations.
Liao TJ; Jang H; Fushman D; Nussinov R
J Chem Phys; 2020 Jul; 153(4):045106. PubMed ID: 32752665
[TBL] [Abstract][Full Text] [Related]
17. Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.
Lock LS; Frigault MM; Saucier C; Park M
J Biol Chem; 2003 Aug; 278(32):30083-90. PubMed ID: 12766170
[TBL] [Abstract][Full Text] [Related]
18. Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1.
Houtman JC; Yamaguchi H; Barda-Saad M; Braiman A; Bowden B; Appella E; Schuck P; Samelson LE
Nat Struct Mol Biol; 2006 Sep; 13(9):798-805. PubMed ID: 16906159
[TBL] [Abstract][Full Text] [Related]
19. Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2.
Harkiolaki M; Tsirka T; Lewitzky M; Simister PC; Joshi D; Bird LE; Jones EY; O'Reilly N; Feller SM
Structure; 2009 Jun; 17(6):809-22. PubMed ID: 19523899
[TBL] [Abstract][Full Text] [Related]
20. Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
Schaeper U; Gehring NH; Fuchs KP; Sachs M; Kempkes B; Birchmeier W
J Cell Biol; 2000 Jun; 149(7):1419-32. PubMed ID: 10871282
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
