409 related articles for article (PubMed ID: 22536986)
1. Analogues of fenarimol are potent inhibitors of Trypanosoma cruzi and are efficacious in a murine model of Chagas disease.
Keenan M; Abbott MJ; Alexander PW; Armstrong T; Best WM; Berven B; Botero A; Chaplin JH; Charman SA; Chatelain E; von Geldern TW; Kerfoot M; Khong A; Nguyen T; McManus JD; Morizzi J; Ryan E; Scandale I; Thompson RA; Wang SZ; White KL
J Med Chem; 2012 May; 55(9):4189-204. PubMed ID: 22536986
[TBL] [Abstract][Full Text] [Related]
2. Design, structure-activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi.
Keenan M; Alexander PW; Diao H; Best WM; Khong A; Kerfoot M; Thompson RC; White KL; Shackleford DM; Ryan E; Gregg AD; Charman SA; von Geldern TW; Scandale I; Chatelain E
Bioorg Med Chem; 2013 Apr; 21(7):1756-63. PubMed ID: 23462713
[TBL] [Abstract][Full Text] [Related]
3. Two analogues of fenarimol show curative activity in an experimental model of Chagas disease.
Keenan M; Chaplin JH; Alexander PW; Abbott MJ; Best WM; Khong A; Botero A; Perez C; Cornwall S; Thompson RA; White KL; Shackleford DM; Koltun M; Chiu FC; Morizzi J; Ryan E; Campbell M; von Geldern TW; Scandale I; Chatelain E; Charman SA
J Med Chem; 2013 Dec; 56(24):10158-70. PubMed ID: 24304150
[TBL] [Abstract][Full Text] [Related]
4. [The chemotherapy of Chagas disease].
Stoppani AO
Medicina (B Aires); 1999; 59 Suppl 2():147-65. PubMed ID: 10668258
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, structure-activity relationship and trypanocidal activity of pyrazole-imidazoline and new pyrazole-tetrahydropyrimidine hybrids as promising chemotherapeutic agents for Chagas disease.
Monteiro ME; Lechuga G; Lara LS; Souto BA; Viganó MG; Bourguignon SC; Calvet CM; Oliveira FOR; Alves CR; Souza-Silva F; Santos MS; Pereira MCS
Eur J Med Chem; 2019 Nov; 182():111610. PubMed ID: 31434040
[TBL] [Abstract][Full Text] [Related]
6. Trypanocidal activity of 5,6-dihydropyran-2-ones against free trypomastigotes forms of Trypanosoma cruzi.
de Fátima A; Marquissolo C; de Albuquerque S; Carraro-Abrahão AA; Pilli RA
Eur J Med Chem; 2006 Oct; 41(10):1210-3. PubMed ID: 16815596
[TBL] [Abstract][Full Text] [Related]
7. Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death.
Magalhaes Moreira DR; de Oliveira AD; Teixeira de Moraes Gomes PA; de Simone CA; Villela FS; Ferreira RS; da Silva AC; dos Santos TA; Brelaz de Castro MC; Pereira VR; Leite AC
Eur J Med Chem; 2014 Mar; 75():467-78. PubMed ID: 24561675
[TBL] [Abstract][Full Text] [Related]
8. Trypanocidal activity and selectivity in vitro of aromatic amidine compounds upon bloodstream and intracellular forms of Trypanosoma cruzi.
De Souza EM; da Silva PB; Nefertiti AS; Ismail MA; Arafa RK; Tao B; Nixon-Smith CK; Boykin DW; Soeiro MN
Exp Parasitol; 2011 Feb; 127(2):429-35. PubMed ID: 20971106
[TBL] [Abstract][Full Text] [Related]
9. Identification of small-molecule inhibitors of Trypansoma cruzi replication.
Germain AR; Carmody LC; Dockendorff C; Galan-Rodriguez C; Rodriguez A; Johnston S; Bittker JA; MacPherson L; Dandapani S; Palmer M; Schreiber SL; Munoz B
Bioorg Med Chem Lett; 2011 Dec; 21(23):7197-200. PubMed ID: 22018462
[TBL] [Abstract][Full Text] [Related]
10. Toxic effects of natural piperine and its derivatives on epimastigotes and amastigotes of Trypanosoma cruzi.
Ribeiro TS; Freire-de-Lima L; Previato JO; Mendonça-Previato L; Heise N; de Lima ME
Bioorg Med Chem Lett; 2004 Jul; 14(13):3555-8. PubMed ID: 15177472
[TBL] [Abstract][Full Text] [Related]
11. Phthalazine derivatives containing imidazole rings behave as Fe-SOD inhibitors and show remarkable anti-T. cruzi activity in immunodeficient-mouse mode of infection.
Sánchez-Moreno M; Gómez-Contreras F; Navarro P; Marín C; Olmo F; Yunta MJ; Sanz AM; Rosales MJ; Cano C; Campayo L
J Med Chem; 2012 Nov; 55(22):9900-13. PubMed ID: 23043291
[TBL] [Abstract][Full Text] [Related]
12. Trypanocidal activity of the phenyl-substituted analogue of furamidine DB569 against Trypanosoma cruzi infection in vivo.
de Souza EM; Oliveira GM; Boykin DW; Kumar A; Hu Q; De Nazaré C Soeiro M
J Antimicrob Chemother; 2006 Sep; 58(3):610-4. PubMed ID: 16854954
[TBL] [Abstract][Full Text] [Related]
13. Antiprotozoal drug nitazoxanide enhances parasitemia, tissue lesions and mortality caused by Trypanosoma cruzi in murine model.
Valle-Reyes JS; Melnikov V; Dobrovinskaya O; Rodriguez-Hernández A; Wookee-Zea C; Pimientel-Rodrigez V; Rueda-Valdovinos G; Delgado-Enciso I; López-Lemus UA; Espinoza-Gómez F
Exp Parasitol; 2017 Jan; 172():44-50. PubMed ID: 28011170
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes).
Schvartzapel AJ; Zhong L; Docampo R; Rodriguez JB; Gros EG
J Med Chem; 1997 Jul; 40(15):2314-22. PubMed ID: 9240347
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of quinones derived from natural product komaroviquinone as anti-Trypanosoma cruzi agents.
Suto Y; Nakajima-Shimada J; Yamagiwa N; Onizuka Y; Iwasaki G
Bioorg Med Chem Lett; 2015 Aug; 25(15):2967-71. PubMed ID: 26037321
[TBL] [Abstract][Full Text] [Related]
16. Benzophenone-based farnesyltransferase inhibitors with high activity against Trypanosoma cruzi.
Esteva MI; Kettler K; Maidana C; Fichera L; Ruiz AM; Bontempi EJ; Andersson B; Dahse HM; Haebel P; Ortmann R; Klebe G; Schlitzer M
J Med Chem; 2005 Nov; 48(23):7186-91. PubMed ID: 16279776
[TBL] [Abstract][Full Text] [Related]
17. Trypanosoma cruzi: in vitro and in vivo antiproliferative effects of epigallocatechin gallate (EGCg).
Güida MC; Esteva MI; Camino A; Flawiá MM; Torres HN; Paveto C
Exp Parasitol; 2007 Oct; 117(2):188-94. PubMed ID: 17673202
[TBL] [Abstract][Full Text] [Related]
18. The efficacy of novel arylimidamides against Trypanosoma cruzi in vitro.
DA Silva CF; Daliry A; DA Silva PB; Akay S; Banerjee M; Farahat AA; Fisher MK; Hu L; Kumar A; Liu Z; Stephens CE; Boykin DW; Correia Soeiro MD
Parasitology; 2011 Dec; 138(14):1863-9. PubMed ID: 21902869
[TBL] [Abstract][Full Text] [Related]
19. Enantiomers of nifurtimox do not exhibit stereoselective anti-Trypanosoma cruzi activity, toxicity, or pharmacokinetic properties.
Moraes CB; White KL; Braillard S; Perez C; Goo J; Gaspar L; Shackleford DM; Cordeiro-da-Silva A; Thompson RC; Freitas-Junior L; Charman SA; Chatelain E
Antimicrob Agents Chemother; 2015; 59(6):3645-7. PubMed ID: 25845874
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents.
Yang PY; Wang M; Li L; Wu H; He CY; Yao SQ
Chemistry; 2012 May; 18(21):6528-41. PubMed ID: 22488888
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]