BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

588 related articles for article (PubMed ID: 22537539)

  • 1. The role of hypoxia-inducible factor-1α and -2α in androgen insensitive prostate cancer cells.
    Jeong CW; Yoon CY; Jeong SJ; Hong SK; Byun SS; Kwak C; Lee SE
    Urol Oncol; 2013 Nov; 31(8):1448-56. PubMed ID: 22537539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Nilsson MB; Zage PE; Zeng L; Xu L; Cascone T; Wu HK; Saigal B; Zweidler-McKay PA; Heymach JV
    Oncogene; 2010 May; 29(20):2938-49. PubMed ID: 20208561
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells.
    Zhao D; Zhai B; He C; Tan G; Jiang X; Pan S; Dong X; Wei Z; Ma L; Qiao H; Jiang H; Sun X
    Cell Signal; 2014 May; 26(5):1030-9. PubMed ID: 24486412
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
    Lim CS; Kiriakidis S; Paleolog EM; Davies AH
    J Vasc Surg; 2012 May; 55(5):1427-39. PubMed ID: 22277691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2.
    Ma L; Li G; Zhu H; Dong X; Zhao D; Jiang X; Li J; Qiao H; Ni S; Sun X
    Cancer Lett; 2014 Dec; 355(1):96-105. PubMed ID: 25218350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia inducible factor 1α and hypoxia inducible factor 2α play distinct and functionally overlapping roles in oral squamous cell carcinoma.
    Zhu GQ; Tang YL; Li L; Zheng M; Jiang J; Li XY; Chen SX; Liang XH
    Clin Cancer Res; 2010 Oct; 16(19):4732-41. PubMed ID: 20807755
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells.
    Palayoor ST; Tofilon PJ; Coleman CN
    Clin Cancer Res; 2003 Aug; 9(8):3150-7. PubMed ID: 12912967
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metformin sensitizes sorafenib to inhibit postoperative recurrence and metastasis of hepatocellular carcinoma in orthotopic mouse models.
    You A; Cao M; Guo Z; Zuo B; Gao J; Zhou H; Li H; Cui Y; Fang F; Zhang W; Song T; Li Q; Zhu X; Yin H; Sun H; Zhang T
    J Hematol Oncol; 2016 Mar; 9():20. PubMed ID: 26957312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions.
    Chae KS; Kang MJ; Lee JH; Ryu BK; Lee MG; Her NG; Ha TK; Han J; Kim YK; Chi SG
    Oncogene; 2011 Mar; 30(10):1213-28. PubMed ID: 21057546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MiR-338-3p inhibits hepatocarcinoma cells and sensitizes these cells to sorafenib by targeting hypoxia-induced factor 1α.
    Xu H; Zhao L; Fang Q; Sun J; Zhang S; Zhan C; Liu S; Zhang Y
    PLoS One; 2014; 9(12):e115565. PubMed ID: 25531114
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hypoxia-independent overexpression of hypoxia-inducible factor 1alpha as an early change in mouse hepatocarcinogenesis.
    Tanaka H; Yamamoto M; Hashimoto N; Miyakoshi M; Tamakawa S; Yoshie M; Tokusashi Y; Yokoyama K; Yaginuma Y; Ogawa K
    Cancer Res; 2006 Dec; 66(23):11263-70. PubMed ID: 17145871
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Suppression of TRPM7 Inhibited Hypoxia-Induced Migration and Invasion of Androgen-Independent Prostate Cancer Cells by Enhancing RACK1-Mediated Degradation of HIF-1
    Yang F; Cai J; Zhan H; Situ J; Li W; Mao Y; Luo Y
    Oxid Med Cell Longev; 2020; 2020():6724810. PubMed ID: 32215176
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HIF isoforms have divergent effects on invasion, metastasis, metabolism and formation of lipid droplets.
    Shah T; Krishnamachary B; Wildes F; Mironchik Y; Kakkad SM; Jacob D; Artemov D; Bhujwalla ZM
    Oncotarget; 2015 Sep; 6(29):28104-19. PubMed ID: 26305551
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment.
    Burkitt K; Chun SY; Dang DT; Dang LH
    Mol Cancer Ther; 2009 May; 8(5):1148-56. PubMed ID: 19435875
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression.
    Harashima N; Takenaga K; Akimoto M; Harada M
    Oncotarget; 2017 Jun; 8(26):42887-42900. PubMed ID: 28476028
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Propofol Reversed Hypoxia-Induced Docetaxel Resistance in Prostate Cancer Cells by Preventing Epithelial-Mesenchymal Transition by Inhibiting Hypoxia-Inducible Factor 1
    Qian J; Shen S; Chen W; Chen N
    Biomed Res Int; 2018; 2018():4174232. PubMed ID: 29568752
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha are expressed in kaposi sarcoma and modulated by insulin-like growth factor-I.
    Catrina SB; Botusan IR; Rantanen A; Catrina AI; Pyakurel P; Savu O; Axelson M; Biberfeld P; Poellinger L; Brismar K
    Clin Cancer Res; 2006 Aug; 12(15):4506-14. PubMed ID: 16899596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.
    Banham AH; Boddy J; Launchbury R; Han C; Turley H; Malone PR; Harris AL; Fox SB
    Prostate; 2007 Jul; 67(10):1091-8. PubMed ID: 17477366
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of 2-methoxyestradiol on apoptosis and HIF-1α and HIF-2α expression in lung cancer cells under normoxia and hypoxia.
    Aquino-Gálvez A; González-Ávila G; Delgado-Tello J; Castillejos-López M; Mendoza-Milla C; Zúñiga J; Checa M; Maldonado-Martínez HA; Trinidad-López A; Cisneros J; Torres-Espíndola LM; Hernández-Jiménez C; Sommer B; Cabello-Gutiérrez C; Gutiérrez-González LH
    Oncol Rep; 2016 Jan; 35(1):577-83. PubMed ID: 26548300
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.