BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

674 related articles for article (PubMed ID: 22538852)

  • 21. Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.
    Merlot AM; Shafie NH; Yu Y; Richardson V; Jansson PJ; Sahni S; Lane DJR; Kovacevic Z; Kalinowski DS; Richardson DR
    Biochem Pharmacol; 2016 Jun; 109():27-47. PubMed ID: 27059255
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
    Liu X; Guo GL; Kong B; Hilburn DB; Hubchak SC; Park S; LeCuyer B; Hsieh A; Wang L; Fang D; Green RM
    Hepatology; 2018 Jul; 68(1):304-316. PubMed ID: 29377207
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation.
    Majumder M; Huang C; Snider MD; Komar AA; Tanaka J; Kaufman RJ; Krokowski D; Hatzoglou M
    Mol Cell Biol; 2012 Mar; 32(5):992-1003. PubMed ID: 22215619
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The molecular mechanisms of XBP-1 gene silencing on IRE1α-TRAF2-ASK1-JNK pathways in oral squamous cell carcinoma under endoplasmic reticulum stress.
    Chen H; Yang H; Pan L; Wang W; Liu X; Ren X; Liu Y; Liu W; Zhang Y; Jiang L; Li K; Zhang B; Wang LX
    Biomed Pharmacother; 2016 Feb; 77():108-13. PubMed ID: 26796273
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway.
    Tsuru A; Imai Y; Saito M; Kohno K
    Sci Rep; 2016 Apr; 6():24217. PubMed ID: 27052593
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T; Chu K; Kodama R; Byun S; Yoon KW; Hiraki M; Mandinova A; Lee SW
    Oncotarget; 2015 Aug; 6(24):19990-20001. PubMed ID: 26254280
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The IRE1α-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis.
    Tohmonda T; Yoda M; Mizuochi H; Morioka H; Matsumoto M; Urano F; Toyama Y; Horiuchi K
    J Biol Chem; 2013 Jan; 288(3):1691-5. PubMed ID: 23235147
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeting Adaptive IRE1α Signaling and PLK2 in Multiple Myeloma: Possible Anti-Tumor Mechanisms of KIRA8 and Nilotinib.
    Yamashita Y; Morita S; Hosoi H; Kobata H; Kishimoto S; Ishibashi T; Mishima H; Kinoshita A; Backes BJ; Yoshiura KI; Papa FR; Sonoki T; Tamura S
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32878237
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1.
    Ling SC; Lau EK; Al-Shabeeb A; Nikolic A; Catalano A; Iland H; Horvath N; Ho PJ; Harrison S; Fleming S; Joshua DE; Allen JD
    Haematologica; 2012 Jan; 97(1):64-72. PubMed ID: 21993678
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mammalian IRE1α dynamically and functionally coalesces with stress granules.
    Liu S; Zhang X; Yao X; Wang G; Huang S; Chen P; Tang M; Cai J; Wu Z; Zhang Y; Xu R; Liu K; He K; Wang Y; Jiang L; Wang QA; Rui L; Liu J; Liu Y
    Nat Cell Biol; 2024 Jun; 26(6):917-931. PubMed ID: 38714852
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Endoplasmic reticulum stress-induced IRE1α activation mediates cross-talk of GSK-3β and XBP-1 to regulate inflammatory cytokine production.
    Kim S; Joe Y; Kim HJ; Kim YS; Jeong SO; Pae HO; Ryter SW; Surh YJ; Chung HT
    J Immunol; 2015 May; 194(9):4498-506. PubMed ID: 25821218
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
    Ming J; Ruan S; Wang M; Ye D; Fan N; Meng Q; Tian B; Huang T
    Oncotarget; 2015 Dec; 6(38):40692-703. PubMed ID: 26517687
    [TBL] [Abstract][Full Text] [Related]  

  • 33. IRE1α-XBP1 pathway promotes melanoma progression by regulating IL-6/STAT3 signaling.
    Chen C; Zhang X
    J Transl Med; 2017 Feb; 15(1):42. PubMed ID: 28222747
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells.
    Yap J; Chen X; Delmotte P; Sieck GC
    Am J Physiol Lung Cell Mol Physiol; 2020 Mar; 318(3):L483-L493. PubMed ID: 31940218
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors.
    Wang L; Perera BG; Hari SB; Bhhatarai B; Backes BJ; Seeliger MA; Schürer SC; Oakes SA; Papa FR; Maly DJ
    Nat Chem Biol; 2012 Dec; 8(12):982-9. PubMed ID: 23086298
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression.
    Qi Y; Wang W; Chen J; Dai L; Kaczorowski D; Gao X; Xia P
    J Biol Chem; 2015 Sep; 290(38):23282-90. PubMed ID: 26240153
    [TBL] [Abstract][Full Text] [Related]  

  • 37. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
    So JS; Cho S; Min SH; Kimball SR; Lee AH
    Mol Cell Biol; 2015 Aug; 35(16):2761-70. PubMed ID: 26031337
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.
    Jiang D; Lynch C; Medeiros BC; Liedtke M; Bam R; Tam AB; Yang Z; Alagappan M; Abidi P; Le QT; Giaccia AJ; Denko NC; Niwa M; Koong AC
    Sci Rep; 2016 Sep; 6():33353. PubMed ID: 27634301
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
    Jiang D; Tam AB; Alagappan M; Hay MP; Gupta A; Kozak MM; Solow-Cordero DE; Lum PY; Denko NC; Giaccia AJ; Le QT; Niwa M; Koong AC
    Mol Cancer Ther; 2016 Sep; 15(9):2055-65. PubMed ID: 27307600
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways.
    Doudican NA; Wen SY; Mazumder A; Orlow SJ
    Oncol Rep; 2012 Nov; 28(5):1851-8. PubMed ID: 22922937
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 34.