These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Cutaneous adverse effects of targeted therapies: Part II: Inhibitors of intracellular molecular signaling pathways. Macdonald JB; Macdonald B; Golitz LE; LoRusso P; Sekulic A J Am Acad Dermatol; 2015 Feb; 72(2):221-36; quiz 237-8. PubMed ID: 25592339 [TBL] [Abstract][Full Text] [Related]
4. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Roberts PJ; Der CJ Oncogene; 2007 May; 26(22):3291-310. PubMed ID: 17496923 [TBL] [Abstract][Full Text] [Related]
5. [Future targeting of the RAS/RAF/MEK/ERK signaling pathway in oncology: the example of melanoma]. Favre G Bull Acad Natl Med; 2014 Feb; 198(2):321-36; discussion 337-8. PubMed ID: 26263707 [TBL] [Abstract][Full Text] [Related]
7. Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy. Friday BB; Adjei AA Clin Cancer Res; 2008 Jan; 14(2):342-6. PubMed ID: 18223206 [TBL] [Abstract][Full Text] [Related]
8. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines. Ulivi P; Arienti C; Amadori D; Fabbri F; Carloni S; Tesei A; Vannini I; Silvestrini R; Zoli W J Cell Physiol; 2009 Jul; 220(1):214-21. PubMed ID: 19288493 [TBL] [Abstract][Full Text] [Related]
9. Cutaneous drug eruptions associated with the use of new oncological drugs. Belloni B; Schönewolf N; Rozati S; Goldinger SM; Dummer R Chem Immunol Allergy; 2012; 97():191-202. PubMed ID: 22613863 [TBL] [Abstract][Full Text] [Related]
10. Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway. Gollob JA; Wilhelm S; Carter C; Kelley SL Semin Oncol; 2006 Aug; 33(4):392-406. PubMed ID: 16890795 [TBL] [Abstract][Full Text] [Related]
11. Targeting the RAF-MEK-ERK pathway in cancer therapy. Montagut C; Settleman J Cancer Lett; 2009 Oct; 283(2):125-34. PubMed ID: 19217204 [TBL] [Abstract][Full Text] [Related]
12. Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors. McCubrey JA; Milella M; Tafuri A; Martelli AM; Lunghi P; Bonati A; Cervello M; Lee JT; Steelman LS Curr Opin Investig Drugs; 2008 Jun; 9(6):614-30. PubMed ID: 18516761 [TBL] [Abstract][Full Text] [Related]
14. 1Alpha,25-dihydroxyvitamin D3-mediated stimulation of steroid sulphatase activity in myeloid leukaemic cell lines requires VDRnuc-mediated activation of the RAS/RAF/ERK-MAP kinase signalling pathway. Hughes PJ; Brown G J Cell Biochem; 2006 Jun; 98(3):590-617. PubMed ID: 16440327 [TBL] [Abstract][Full Text] [Related]
15. Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy. Steelman LS; Franklin RA; Abrams SL; Chappell W; Kempf CR; Bäsecke J; Stivala F; Donia M; Fagone P; Nicoletti F; Libra M; Ruvolo P; Ruvolo V; Evangelisti C; Martelli AM; McCubrey JA Leukemia; 2011 Jul; 25(7):1080-94. PubMed ID: 21494257 [TBL] [Abstract][Full Text] [Related]
16. Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1. Gysin S; Lee SH; Dean NM; McMahon M Cancer Res; 2005 Jun; 65(11):4870-80. PubMed ID: 15930308 [TBL] [Abstract][Full Text] [Related]
17. [Focus on targeting the Ras-MAPK pathway: the Mek inhibitors]. Baldini C; Duchemann B; Hollebecque A; Routier É; Varga A; Gazzah A; Bahleda R; Besse B; Soria JC; Massard C Bull Cancer; 2012 Sep; 99(9):865-74. PubMed ID: 25471668 [TBL] [Abstract][Full Text] [Related]
18. Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders. Schad K; Baumann Conzett K; Zipser MC; Enderlin V; Kamarashev J; French LE; Dummer R Clin Cancer Res; 2010 Feb; 16(3):1058-64. PubMed ID: 20103661 [TBL] [Abstract][Full Text] [Related]
19. RAF inhibition and induction of cutaneous squamous cell carcinoma. Robert C; Arnault JP; Mateus C Curr Opin Oncol; 2011 Mar; 23(2):177-82. PubMed ID: 21192261 [TBL] [Abstract][Full Text] [Related]
20. The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer. Shimizu T; Tolcher AW; Papadopoulos KP; Beeram M; Rasco DW; Smith LS; Gunn S; Smetzer L; Mays TA; Kaiser B; Wick MJ; Alvarez C; Cavazos A; Mangold GL; Patnaik A Clin Cancer Res; 2012 Apr; 18(8):2316-25. PubMed ID: 22261800 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]