BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 22540932)

  • 1. Enhancement of cyclopamine via conjugation with nonmetabolic sugars.
    Goff RD; Thorson JS
    Org Lett; 2012 May; 14(10):2454-7. PubMed ID: 22540932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine.
    Winkler JD; Isaacs A; Holderbaum L; Tatard V; Dahmane N
    Org Lett; 2009 Jul; 11(13):2824-7. PubMed ID: 19552464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exo-cyclopamine--a stable and potent inhibitor of hedgehog-signaling.
    Heretsch P; Büttner A; Tzagkaroulaki L; Zahn S; Kirchner B; Giannis A
    Chem Commun (Camb); 2011 Jul; 47(26):7362-4. PubMed ID: 21589966
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Veratrum and Solanum alkaloids.
    Heretsch P; Giannis A
    Alkaloids Chem Biol; 2015; 74():201-32. PubMed ID: 25845062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hydroxylated cyclopamine analogues from Veratrum californicum and their hedgehog pathway inhibiting activity.
    Chianese G; Lopatriello A; Sirignano C; Andreani A; Gambini A; De Combarieu E; Stornaiuolo M; Taglialatela-Scafati O
    Bioorg Med Chem; 2023 Apr; 84():117265. PubMed ID: 37001245
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of all diastereomers of the piperidine--alkaloid substructure of cyclopamine.
    Heretsch P; Rabe S; Giannis A
    Org Lett; 2009 Dec; 11(23):5410-2. PubMed ID: 19883099
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of cyclopamine using a biomimetic and diastereoselective approach.
    Giannis A; Heretsch P; Sarli V; Stössel A
    Angew Chem Int Ed Engl; 2009; 48(42):7911-4. PubMed ID: 19591183
    [No Abstract]   [Full Text] [Related]  

  • 8. Divergent and gram-scale syntheses of (-)-veratramine and (-)-cyclopamine.
    Hou W; Lin H; Wu Y; Li C; Chen J; Liu XY; Qin Y
    Nat Commun; 2024 Jun; 15(1):5332. PubMed ID: 38909052
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.
    Tremblay MR; Nevalainen M; Nair SJ; Porter JR; Castro AC; Behnke ML; Yu LC; Hagel M; White K; Faia K; Grenier L; Campbell MJ; Cushing J; Woodward CN; Hoyt J; Foley MA; Read MA; Sydor JR; Tong JK; Palombella VJ; McGovern K; Adams J
    J Med Chem; 2008 Nov; 51(21):6646-9. PubMed ID: 18842035
    [TBL] [Abstract][Full Text] [Related]  

  • 10. One Hundred Faces of Cyclopamine.
    Iovine V; Mori M; Calcaterra A; Berardozzi S; Botta B
    Curr Pharm Des; 2016; 22(12):1658-81. PubMed ID: 26759083
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of A B C-ring subunit of C-nor-D-homo-steroidal alkaloids: towards the total synthesis of cyclopamine.
    Zhang XL; Liao YQ; Cai PJ; Yao HQ; Kong LY; Sun HB
    Chin J Nat Med; 2013 May; 11(3):277-83. PubMed ID: 23725842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new cyclopamine glucuronide prodrug with improved kinetics of drug release.
    Renoux B; Legigan T; Bensalma S; Chadéneau C; Muller JM; Papot S
    Org Biomol Chem; 2011 Dec; 9(24):8459-64. PubMed ID: 22042246
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and anticancer activity studies of cyclopamine derivatives.
    Zhang J; Garrossian M; Gardner D; Garrossian A; Chang YT; Kim YK; Chang CW
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1359-63. PubMed ID: 18221872
    [TBL] [Abstract][Full Text] [Related]  

  • 14. I only have eye for ewe: the discovery of cyclopamine and development of Hedgehog pathway-targeting drugs.
    Chen JK
    Nat Prod Rep; 2016 May; 33(5):595-601. PubMed ID: 26787175
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A convenient and efficient one-pot conversion of peimisine into cyclopamine.
    Zheng SY; Tan HS; Tao JS; Shen ZW
    Fitoterapia; 2012 Oct; 83(7):1238-41. PubMed ID: 22735603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cyclopamine bioactivity by extraction method from Veratrum californicum.
    Turner MW; Cruz R; Mattos J; Baughman N; Elwell J; Fothergill J; Nielsen A; Brookhouse J; Bartlett A; Malek P; Pu X; King MD; McDougal OM
    Bioorg Med Chem; 2016 Aug; 24(16):3752-7. PubMed ID: 27338657
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclopamine, a naturally occurring alkaloid, and its analogues may find wide applications in cancer therapy.
    Ma H; Li HQ; Zhang X
    Curr Top Med Chem; 2013; 13(17):2208-15. PubMed ID: 23978132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A piperidine chiron for the Veratrum alkaloids.
    Taber DF; DeMatteo PW
    J Org Chem; 2012 May; 77(9):4235-41. PubMed ID: 22401662
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cyclopamine: from cyclops lambs to cancer treatment.
    Lee ST; Welch KD; Panter KE; Gardner DR; Garrossian M; Chang CW
    J Agric Food Chem; 2014 Jul; 62(30):7355-62. PubMed ID: 24754790
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum.
    Tang J; Li HL; Shen YH; Jin HZ; Yan SK; Liu XH; Zeng HW; Liu RH; Tan YX; Zhang WD
    Phytother Res; 2010 Jun; 24(6):821-6. PubMed ID: 20013819
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.