These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 2254311)

  • 1. Probing the role of glutamic acid 144 in the EcoRI endonuclease using aspartic acid and glutamine replacements.
    Hager PW; Reich NO; Day JP; Coche TG; Boyer HW; Rosenberg JM; Greene PJ
    J Biol Chem; 1990 Dec; 265(35):21520-6. PubMed ID: 2254311
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutational analysis of the function of Gln115 in the EcoRI restriction endonuclease, a critical amino acid for recognition of the inner thymidine residue in the sequence -GAATTC- and for coupling specific DNA binding to catalysis.
    Jeltsch A; Alves J; Oelgeschläger T; Wolfes H; Maass G; Pingoud A
    J Mol Biol; 1993 Jan; 229(1):221-34. PubMed ID: 8421302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stereoselective interaction with chiral phosphorothioates at the central DNA kink of the EcoRI endonuclease-GAATTC complex.
    Lesser DR; Grajkowski A; Kurpiewski MR; Koziolkiewicz M; Stec WJ; Jen-Jacobson L
    J Biol Chem; 1992 Dec; 267(34):24810-8. PubMed ID: 1447218
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Changing the hydrogen-bonding potential in the DNA binding site of EcoRI by site-directed mutagenesis drastically reduces the enzymatic activity, not, however, the preference of this restriction endonuclease for cleavage within the site-GAATTC-.
    Alves J; Rüter T; Geiger R; Fliess A; Maass G; Pingoud A
    Biochemistry; 1989 Mar; 28(6):2678-84. PubMed ID: 2659077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Asn141 is essential for DNA recognition by EcoRI restriction endonuclease.
    Fritz A; Küster W; Alves J
    FEBS Lett; 1998 Oct; 438(1-2):66-70. PubMed ID: 9821960
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determinants of EcoRI endonuclease sequence discrimination.
    Needels MC; Fried SR; Love R; Rosenberg JM; Boyer HW; Greene PJ
    Proc Natl Acad Sci U S A; 1989 May; 86(10):3579-83. PubMed ID: 2657723
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A dodecapeptide comprising the extended chain-alpha 4 region of the restriction endonuclease EcoRI specifically binds to the EcoRI recognition site.
    Jeltsch A; Alves J; Urbanke C; Maass G; Eckstein H; Lianshan Z; Bayer E; Pingoud A
    J Biol Chem; 1995 Mar; 270(10):5122-9. PubMed ID: 7890621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thermodynamic and kinetic basis for the relaxed DNA sequence specificity of "promiscuous" mutant EcoRI endonucleases.
    Sapienza PJ; Dela Torre CA; McCoy WH; Jana SV; Jen-Jacobson L
    J Mol Biol; 2005 Apr; 348(2):307-24. PubMed ID: 15811370
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Site-directed mutagenesis in the catalytic center of the restriction endonuclease EcoRI.
    Grabowski G; Jeltsch A; Wolfes H; Maass G; Alves J
    Gene; 1995 May; 157(1-2):113-8. PubMed ID: 7607470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Asp-59 is not important for the catalytic activity of the restriction endonuclease EcoRI.
    Grabowski G; Maass G; Alves J
    FEBS Lett; 1996 Feb; 381(1-2):106-10. PubMed ID: 8641414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The highly homologous isoschizomers RsrI endonuclease and EcoRI endonuclease do not recognize their target sequence identically.
    Aiken CR; McLaughlin LW; Gumport RI
    J Biol Chem; 1991 Oct; 266(28):19070-8. PubMed ID: 1918026
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How the EcoRI endonuclease recognizes and cleaves DNA.
    Heitman J
    Bioessays; 1992 Jul; 14(7):445-54. PubMed ID: 1445286
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants.
    Flores H; Osuna J; Heitman J; Soberón X
    Gene; 1995 May; 157(1-2):295-301. PubMed ID: 7607511
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutants of the EcoRI endonuclease with promiscuous substrate specificity implicate residues involved in substrate recognition.
    Heitman J; Model P
    EMBO J; 1990 Oct; 9(10):3369-78. PubMed ID: 2209548
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of enzyme-substrate contacts located outside the EcoRI recognition site on cleavage of duplex oligodeoxyribonucleotide substrates by EcoRI endonuclease.
    Van Cleve MD; Gumport RI
    Biochemistry; 1992 Jan; 31(2):334-9. PubMed ID: 1731891
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutational analysis of the function of Met137 and Ile197, two amino acids implicated in sequence-specific DNA recognition by the EcoRI endonuclease.
    Ivanenko T; Heitman J; Kiss A
    Biol Chem; 1998; 379(4-5):459-65. PubMed ID: 9628338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substrate recognition by the EcoRI endonuclease.
    Heitman J; Model P
    Proteins; 1990; 7(2):185-97. PubMed ID: 2139225
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI- and FokI-like catalytic domains.
    Armalyte E; Bujnicki JM; Giedriene J; Gasiunas G; Kosiński J; Lubys A
    J Biol Chem; 2005 Dec; 280(50):41584-94. PubMed ID: 16223716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An EcoRI-RsrI chimeric restriction endonuclease retains parental sequence specificity.
    Chuluunbaatar T; Ivanenko-Johnston T; Fuxreiter M; Meleshko R; Raskó T; Simon I; Heitman J; Kiss A
    Biochim Biophys Acta; 2007 May; 1774(5):583-94. PubMed ID: 17442645
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The negative charge of Glu-111 is required to activate the cleavage center of EcoRI endonuclease.
    Wright DJ; King K; Modrich P
    J Biol Chem; 1989 Jul; 264(20):11816-21. PubMed ID: 2745418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.