244 related articles for article (PubMed ID: 22547224)
1. A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins.
Eykelenboom JE; Briggs GJ; Bradshaw NJ; Soares DC; Ogawa F; Christie S; Malavasi EL; Makedonopoulou P; Mackie S; Malloy MP; Wear MA; Blackburn EA; Bramham J; McIntosh AM; Blackwood DH; Muir WJ; Porteous DJ; Millar JK
Hum Mol Genet; 2012 Aug; 21(15):3374-86. PubMed ID: 22547224
[TBL] [Abstract][Full Text] [Related]
2. DISC1 and DISC2: discovering and dissecting molecular mechanisms underlying psychiatric illness.
Millar JK; James R; Brandon NJ; Thomson PA
Ann Med; 2004; 36(5):367-78. PubMed ID: 15478311
[TBL] [Abstract][Full Text] [Related]
3. Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.
Blackwood DH; Fordyce A; Walker MT; St Clair DM; Porteous DJ; Muir WJ
Am J Hum Genet; 2001 Aug; 69(2):428-33. PubMed ID: 11443544
[TBL] [Abstract][Full Text] [Related]
4. Chromosomal location and genomic structure of the human translin-associated factor X gene (TRAX; TSNAX) revealed by intergenic splicing to DISC1, a gene disrupted by a translocation segregating with schizophrenia.
Millar JK; Christie S; Semple CA; Porteous DJ
Genomics; 2000 Jul; 67(1):69-77. PubMed ID: 10945471
[TBL] [Abstract][Full Text] [Related]
5. The cortical thickness phenotype of individuals with DISC1 translocation resembles schizophrenia.
Doyle OM; Bois C; Thomson P; Romaniuk L; Whitcher B; Williams SC; Turkheimer FE; Stefansson H; McIntosh AM; Mehta MA; Lawrie SM
J Clin Invest; 2015 Sep; 125(9):3714-22. PubMed ID: 26301809
[TBL] [Abstract][Full Text] [Related]
6. Disruption of two novel genes by a translocation co-segregating with schizophrenia.
Millar JK; Wilson-Annan JC; Anderson S; Christie S; Taylor MS; Semple CA; Devon RS; St Clair DM; Muir WJ; Blackwood DH; Porteous DJ
Hum Mol Genet; 2000 May; 9(9):1415-23. PubMed ID: 10814723
[TBL] [Abstract][Full Text] [Related]
7. Effects of a Balanced Translocation between Chromosomes 1 and 11 Disrupting the DISC1 Locus on White Matter Integrity.
Whalley HC; Dimitrova R; Sprooten E; Dauvermann MR; Romaniuk L; Duff B; Watson AR; Moorhead B; Bastin M; Semple SI; Giles S; Hall J; Thomson P; Roberts N; Hughes ZA; Brandon NJ; Dunlop J; Whitcher B; Blackwood DH; McIntosh AM; Lawrie SM
PLoS One; 2015; 10(6):e0130900. PubMed ID: 26102360
[TBL] [Abstract][Full Text] [Related]
8. Boymaw, overexpressed in brains with major psychiatric disorders, may encode a small protein to inhibit mitochondrial function and protein translation.
Ji B; Kim M; Higa KK; Zhou X
Am J Med Genet B Neuropsychiatr Genet; 2015 Jun; 168B(4):284-95. PubMed ID: 25943690
[TBL] [Abstract][Full Text] [Related]
9. DISC1-dependent Regulation of Mitochondrial Dynamics Controls the Morphogenesis of Complex Neuronal Dendrites.
Norkett R; Modi S; Birsa N; Atkin TA; Ivankovic D; Pathania M; Trossbach SV; Korth C; Hirst WD; Kittler JT
J Biol Chem; 2016 Jan; 291(2):613-29. PubMed ID: 26553875
[TBL] [Abstract][Full Text] [Related]
10. Construction of balanced translocation t(1;11)(q42.1;q14.3) probe and screening application in genomic samples in Taiwan.
Liu YL; Liu CM; Tien HF; Hwu HG
J Formos Med Assoc; 2009 Jul; 108(7):587-91. PubMed ID: 19586833
[TBL] [Abstract][Full Text] [Related]
11. DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness.
Malavasi ELV; Economides KD; Grünewald E; Makedonopoulou P; Gautier P; Mackie S; Murphy LC; Murdoch H; Crummie D; Ogawa F; McCartney DL; O'Sullivan ST; Burr K; Torrance HS; Phillips J; Bonneau M; Anderson SM; Perry P; Pearson M; Constantinides C; Davidson-Smith H; Kabiri M; Duff B; Johnstone M; Polites HG; Lawrie SM; Blackwood DH; Semple CA; Evans KL; Didier M; Chandran S; McIntosh AM; Price DJ; Houslay MD; Porteous DJ; Millar JK
Transl Psychiatry; 2018 Sep; 8(1):184. PubMed ID: 30190480
[TBL] [Abstract][Full Text] [Related]
12. A frameshift mutation in Disrupted in Schizophrenia 1 in an American family with schizophrenia and schizoaffective disorder.
Sachs NA; Sawa A; Holmes SE; Ross CA; DeLisi LE; Margolis RL
Mol Psychiatry; 2005 Aug; 10(8):758-64. PubMed ID: 15940305
[TBL] [Abstract][Full Text] [Related]
13. Questions about DISC1 as a genetic risk factor for schizophrenia.
Sullivan PF
Mol Psychiatry; 2013 Oct; 18(10):1050-2. PubMed ID: 24056909
[No Abstract] [Full Text] [Related]
14. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.
Hennah W; Thomson P; Peltonen L; Porteous D
Schizophr Bull; 2006 Jul; 32(3):409-16. PubMed ID: 16699061
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders.
Ji B; Higa KK; Kim M; Zhou L; Young JW; Geyer MA; Zhou X
Hum Mol Genet; 2014 Nov; 23(21):5683-705. PubMed ID: 24908665
[TBL] [Abstract][Full Text] [Related]
16. Analysis of the DISC1 translocation partner (11q14.3) in genetic risk of schizophrenia.
Debono R; Topless R; Markie D; Black MA; Merriman TR
Genes Brain Behav; 2012 Oct; 11(7):859-63. PubMed ID: 22891933
[TBL] [Abstract][Full Text] [Related]
17. Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.
Hodgkinson CA; Goldman D; Jaeger J; Persaud S; Kane JM; Lipsky RH; Malhotra AK
Am J Hum Genet; 2004 Nov; 75(5):862-72. PubMed ID: 15386212
[TBL] [Abstract][Full Text] [Related]
18. Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder.
Devon RS; Anderson S; Teague PW; Burgess P; Kipari TM; Semple CA; Millar JK; Muir WJ; Murray V; Pelosi AJ; Blackwood DH; Porteous DJ
Psychiatr Genet; 2001 Jun; 11(2):71-8. PubMed ID: 11525420
[TBL] [Abstract][Full Text] [Related]
19. Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.
Millar JK; Christie S; Anderson S; Lawson D; Hsiao-Wei Loh D; Devon RS; Arveiler B; Muir WJ; Blackwood DH; Porteous DJ
Mol Psychiatry; 2001 Mar; 6(2):173-8. PubMed ID: 11317219
[TBL] [Abstract][Full Text] [Related]
20. Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness.
Bonneau M; Sullivan STO; Gonzalez-Lozano MA; Baxter P; Gautier P; Marchisella E; Hardingham NR; Chesters RA; Torrance H; Howard DM; Jansen MA; McMillan M; Singh Y; Didier M; Koopmans F; Semple CA; McIntosh AM; Volkmer H; Loos M; Fox K; Hardingham GE; Vernon AC; Porteous DJ; Smit AB; Price DJ; Kirsty Millar J
Transl Psychiatry; 2021 Feb; 11(1):135. PubMed ID: 33608504
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
