BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

116 related articles for article (PubMed ID: 22549023)

  • 21. Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies.
    Nakamura K; Fujioka S; Fukumoto S; Inoue N; Sakamoto K; Hirata H; Kido Y; Yabu Y; Suzuki T; Watanabe Y; Saimoto H; Akiyama H; Kita K
    Parasitol Int; 2010 Dec; 59(4):560-4. PubMed ID: 20688188
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Targeting Cysteine Proteases and their Inhibitors to Combat Trypanosomiasis.
    Saha A; Pushpa ; Moitra S; Basak D; Brahma S; Mondal D; Molla SH; Samadder A; Nandi S
    Curr Med Chem; 2024; 31(16):2135-2169. PubMed ID: 37340748
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
    Redecke L; Nass K; DePonte DP; White TA; Rehders D; Barty A; Stellato F; Liang M; Barends TRM; Boutet S; Williams GJ; Messerschmidt M; Seibert MM; Aquila A; Arnlund D; Bajt S; Barth T; Bogan MJ; Caleman C; Chao TC; Doak RB; Fleckenstein H; Frank M; Fromme R; Galli L; Grotjohann I; Hunter MS; Johansson LC; Kassemeyer S; Katona G; Kirian RA; Koopmann R; Kupitz C; Lomb L; Martin AV; Mogk S; Neutze R; Shoeman RL; Steinbrener J; Timneanu N; Wang D; Weierstall U; Zatsepin NA; Spence JCH; Fromme P; Schlichting I; Duszenko M; Betzel C; Chapman HN
    Science; 2013 Jan; 339(6116):227-230. PubMed ID: 23196907
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L.
    Costa TF; dos Reis FC; Lima AP
    Biochim Biophys Acta; 2012 Mar; 1824(3):493-501. PubMed ID: 22234330
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A cathepsin L-specific inhibitor preferentially inhibits degradation of autophagosomal LC3 and GABARAP in HeLa and Huh-7 cells.
    Ueno T; Takahashi K
    Autophagy; 2009 Aug; 5(6):878-9. PubMed ID: 19535915
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents.
    Vicik R; Hoerr V; Glaser M; Schultheis M; Hansell E; McKerrow JH; Holzgrabe U; Caffrey CR; Ponte-Sucre A; Moll H; Stich A; Schirmeister T
    Bioorg Med Chem Lett; 2006 May; 16(10):2753-7. PubMed ID: 16516467
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei.
    Kerr ID; Wu P; Marion-Tsukamaki R; Mackey ZB; Brinen LS
    PLoS Negl Trop Dis; 2010 Jun; 4(6):e701. PubMed ID: 20544024
    [TBL] [Abstract][Full Text] [Related]  

  • 28. An intracellular form of cathepsin B contributes to invasiveness in cancer.
    Szpaderska AM; Frankfater A
    Cancer Res; 2001 Apr; 61(8):3493-500. PubMed ID: 11309313
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Cathepsin B inhibition prevents trypsinogen activation and reduces pancreatitis severity.
    Van Acker GJ; Saluja AK; Bhagat L; Singh VP; Song AM; Steer ML
    Am J Physiol Gastrointest Liver Physiol; 2002 Sep; 283(3):G794-800. PubMed ID: 12181196
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis.
    Ettari R; Tamborini L; Angelo IC; Micale N; Pinto A; De Micheli C; Conti P
    J Med Chem; 2013 Jul; 56(14):5637-58. PubMed ID: 23611656
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cell morphogenesis of Trypanosoma brucei requires the paralogous, differentially expressed calpain-related proteins CAP5.5 and CAP5.5V.
    Olego-Fernandez S; Vaughan S; Shaw MK; Gull K; Ginger ML
    Protist; 2009 Nov; 160(4):576-90. PubMed ID: 19656721
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cysteine proteinase inhibitors kill cultured bloodstream forms of Trypanosoma brucei brucei.
    Troeberg L; Morty RE; Pike RN; Lonsdale-Eccles JD; Palmer JT; McKerrow JH; Coetzer TH
    Exp Parasitol; 1999 Apr; 91(4):349-55. PubMed ID: 10092479
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A multiplex PCR that discriminates between Trypanosoma brucei brucei and zoonotic T. b. rhodesiense.
    Picozzi K; Carrington M; Welburn SC
    Exp Parasitol; 2008 Jan; 118(1):41-6. PubMed ID: 17643434
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Antiprotozoal and cytotoxic screening of 45 plant extracts from Democratic Republic of Congo.
    Mesia GK; Tona GL; Nanga TH; Cimanga RK; Apers S; Cos P; Maes L; Pieters L; Vlietinck AJ
    J Ethnopharmacol; 2008 Feb; 115(3):409-15. PubMed ID: 18068320
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei.
    Kelner A; Tinti M; Guther MLS; Foth BJ; Chappell L; Berriman M; Cowling VH; Ferguson MAJ
    PLoS One; 2018; 13(7):e0201263. PubMed ID: 30040830
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Cathepsin L of Triatoma brasiliensis (Reduviidae, Triatominae): sequence characterization, expression pattern and zymography.
    Waniek PJ; Pacheco Costa JE; Jansen AM; Costa J; Araújo CA
    J Insect Physiol; 2012 Jan; 58(1):178-87. PubMed ID: 22100382
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Genes of cathepsin L-like proteases in Trypanosoma rangeli isolates: markers for diagnosis, genotyping and phylogenetic relationships.
    Ortiz PA; Maia da Silva F; Cortez AP; Lima L; Campaner M; Pral EM; Alfieri SC; Teixeira MM
    Acta Trop; 2009 Dec; 112(3):249-59. PubMed ID: 19683503
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target.
    Mina JG; Pan SY; Wansadhipathi NK; Bruce CR; Shams-Eldin H; Schwarz RT; Steel PG; Denny PW
    Mol Biochem Parasitol; 2009 Nov; 168(1):16-23. PubMed ID: 19545591
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Leishmania major: comparison of the cathepsin L- and B-like cysteine protease genes with those of other trypanosomatids.
    Sakanari JA; Nadler SA; Chan VJ; Engel JC; Leptak C; Bouvier J
    Exp Parasitol; 1997 Jan; 85(1):63-76. PubMed ID: 9024203
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Stuck in reverse: loss of LC1 in Trypanosoma brucei disrupts outer dynein arms and leads to reverse flagellar beat and backward movement.
    Baron DM; Kabututu ZP; Hill KL
    J Cell Sci; 2007 May; 120(Pt 9):1513-20. PubMed ID: 17405810
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.