BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 22555804)

  • 1. Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells.
    Swiatek-Machado K; Mieczkowski J; Ellert-Miklaszewska A; Swierk P; Fokt I; Szymanski S; Skora S; Szeja W; Grynkiewicz G; Lesyng B; Priebe W; Kaminska B
    Cancer Biol Ther; 2012 Jun; 13(8):657-70. PubMed ID: 22555804
    [TBL] [Abstract][Full Text] [Related]  

  • 2. JAK/STAT pathway plays a critical role in the proinflammatory gene expression and apoptosis of RAW264.7 cells induced by trichothecenes as DON and T-2 toxin.
    Wang X; Liu Q; Ihsan A; Huang L; Dai M; Hao H; Cheng G; Liu Z; Wang Y; Yuan Z
    Toxicol Sci; 2012 Jun; 127(2):412-24. PubMed ID: 22454431
    [TBL] [Abstract][Full Text] [Related]  

  • 3. JAK2 tyrosine kinase inhibitor AG490 suppresses cell growth and invasion of gallbladder cancer cells via inhibition of JAK2/STAT3 signaling.
    Fu LX; Lian QW; Pan JD; Xu ZL; Zhou TM; Ye B
    J Biol Regul Homeost Agents; 2017; 31(1):51-58. PubMed ID: 28337870
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A small-molecule compound identified through a cell-based screening inhibits JAK/STAT pathway signaling in human cancer cells.
    Kim BH; Yin CH; Guo Q; Bach EA; Lee H; Sandoval C; Jayabose S; Ulaczyk-Lesanko A; Hall DG; Baeg GH
    Mol Cancer Ther; 2008 Sep; 7(9):2672-80. PubMed ID: 18790749
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells.
    Wang Y; Ma X; Yan S; Shen S; Zhu H; Gu Y; Wang H; Qin G; Yu Q
    Cancer Res; 2009 Sep; 69(18):7302-10. PubMed ID: 19706767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MAPK and JAK-STAT signaling pathways are involved in the oxidative stress-induced decrease in expression of surfactant protein genes.
    Park SK; Dahmer MK; Quasney MW
    Cell Physiol Biochem; 2012; 30(2):334-46. PubMed ID: 22739240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel inhibitor of the STAT3 pathway induces apoptosis in malignant glioma cells both in vitro and in vivo.
    Iwamaru A; Szymanski S; Iwado E; Aoki H; Yokoyama T; Fokt I; Hess K; Conrad C; Madden T; Sawaya R; Kondo S; Priebe W; Kondo Y
    Oncogene; 2007 Apr; 26(17):2435-44. PubMed ID: 17043651
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.
    Kreis S; Munz GA; Haan S; Heinrich PC; Behrmann I
    Mol Cancer Res; 2007 Dec; 5(12):1331-41. PubMed ID: 18171991
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the signal transducers and activators of transcription (STAT) 3 signalling pathway by AG490 in laryngeal carcinoma cells.
    Zhang H; Zhang D; Luan X; Xie G; Pan X
    J Int Med Res; 2010; 38(5):1673-81. PubMed ID: 21309481
    [TBL] [Abstract][Full Text] [Related]  

  • 10. WP1066 suppresses macrophage cell death induced by inflammasome agonists independently of its inhibitory effect on STAT3.
    Honda S; Sadatomi D; Yamamura Y; Nakashioya K; Tanimura S; Takeda K
    Cancer Sci; 2017 Mar; 108(3):520-527. PubMed ID: 28035720
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Curcumin-Mediated Apoptotic Cell Death in Papillary Thyroid Cancer and Cancer Stem-Like Cells through Targeting of the JAK/STAT3 Signaling Pathway.
    Khan AQ; Ahmed EI; Elareer N; Fathima H; Prabhu KS; Siveen KS; Kulinski M; Azizi F; Dermime S; Ahmad A; Steinhoff M; Uddin S
    Int J Mol Sci; 2020 Jan; 21(2):. PubMed ID: 31936675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells.
    Senft C; Priester M; Polacin M; Schröder K; Seifert V; Kögel D; Weissenberger J
    J Neurooncol; 2011 Feb; 101(3):393-403. PubMed ID: 20589525
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling.
    Zhu F; Dai C; Fu Y; Loo JF; Xia D; Gao SP; Ma Z; Chen Z
    Oncotarget; 2016 Feb; 7(8):9462-76. PubMed ID: 26843613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.
    Yang F; Brown C; Buettner R; Hedvat M; Starr R; Scuto A; Schroeder A; Jensen M; Jove R
    Mol Cancer Ther; 2010 Apr; 9(4):953-62. PubMed ID: 20371721
    [TBL] [Abstract][Full Text] [Related]  

  • 15. JAK/STAT3 signaling is required for TGF-β-induced epithelial-mesenchymal transition in lung cancer cells.
    Liu RY; Zeng Y; Lei Z; Wang L; Yang H; Liu Z; Zhao J; Zhang HT
    Int J Oncol; 2014 May; 44(5):1643-51. PubMed ID: 24573038
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pterostilbene exerts antitumor activity against human osteosarcoma cells by inhibiting the JAK2/STAT3 signaling pathway.
    Liu Y; Wang L; Wu Y; Lv C; Li X; Cao X; Yang M; Feng D; Luo Z
    Toxicology; 2013 Feb; 304():120-31. PubMed ID: 23313376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of a JAK inhibitor, AG490, on proliferation and apoptosis of human nasopharyngeal carcinoma cell line CNE-2Z.
    Wu MH; Chen XY; Cai KR
    Ai Zheng; 2009 Jan; 28(1):24-8. PubMed ID: 19448411
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines.
    Barton BE; Karras JG; Murphy TF; Barton A; Huang HF
    Mol Cancer Ther; 2004 Jan; 3(1):11-20. PubMed ID: 14749471
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.
    Liu L; Nam S; Tian Y; Yang F; Wu J; Wang Y; Scuto A; Polychronopoulos P; Magiatis P; Skaltsounis L; Jove R
    Cancer Res; 2011 Jun; 71(11):3972-9. PubMed ID: 21610112
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Silibinin inhibits constitutive activation of Stat3, and causes caspase activation and apoptotic death of human prostate carcinoma DU145 cells.
    Agarwal C; Tyagi A; Kaur M; Agarwal R
    Carcinogenesis; 2007 Jul; 28(7):1463-70. PubMed ID: 17341659
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.