BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

339 related articles for article (PubMed ID: 22558232)

  • 1. Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation.
    Krejci P; Aklian A; Kaucka M; Sevcikova E; Prochazkova J; Masek JK; Mikolka P; Pospisilova T; Spoustova T; Weis M; Paznekas WA; Wolf JH; Gutkind JS; Wilcox WR; Kozubik A; Jabs EW; Bryja V; Salazar L; Vesela I; Balek L
    PLoS One; 2012; 7(4):e35826. PubMed ID: 22558232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.
    Červenka I; Wolf J; Mašek J; Krejci P; Wilcox WR; Kozubík A; Schulte G; Gutkind JS; Bryja V
    Mol Cell Biol; 2011 Jan; 31(1):179-89. PubMed ID: 20974802
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MiR-126 promotes coxsackievirus replication by mediating cross-talk of ERK1/2 and Wnt/β-catenin signal pathways.
    Ye X; Hemida MG; Qiu Y; Hanson PJ; Zhang HM; Yang D
    Cell Mol Life Sci; 2013 Dec; 70(23):4631-44. PubMed ID: 23811937
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage.
    Buchtova M; Oralova V; Aklian A; Masek J; Vesela I; Ouyang Z; Obadalova T; Konecna Z; Spoustova T; Pospisilova T; Matula P; Varecha M; Balek L; Gudernova I; Jelinkova I; Duran I; Cervenkova I; Murakami S; Kozubik A; Dvorak P; Bryja V; Krejci P
    Biochim Biophys Acta; 2015 May; 1852(5):839-50. PubMed ID: 25558817
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphorylation of PPP(S/T)P motif of the free LRP6 intracellular domain is not required to activate the Wnt/beta-catenin pathway and attenuate GSK3beta activity.
    Beagle B; Mi K; Johnson GV
    J Cell Biochem; 2009 Nov; 108(4):886-95. PubMed ID: 19711366
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine phosphorylation of LRP6 by Src and Fer inhibits Wnt/β-catenin signalling.
    Chen Q; Su Y; Wesslowski J; Hagemann AI; Ramialison M; Wittbrodt J; Scholpp S; Davidson G
    EMBO Rep; 2014 Dec; 15(12):1254-67. PubMed ID: 25391905
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tyrosine-based signal mediates LRP6 receptor endocytosis and desensitization of Wnt/β-catenin pathway signaling.
    Liu CC; Kanekiyo T; Roth B; Bu G
    J Biol Chem; 2014 Oct; 289(40):27562-70. PubMed ID: 25143377
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity.
    Valvezan AJ; Zhang F; Diehl JA; Klein PS
    J Biol Chem; 2012 Feb; 287(6):3823-32. PubMed ID: 22184111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
    Park DS; Seo JH; Hong M; Choi SC
    Biochem Biophys Res Commun; 2013 Jun; 436(2):338-43. PubMed ID: 23743195
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of GSK3 by Wnt signalling--two contrasting models.
    Metcalfe C; Bienz M
    J Cell Sci; 2011 Nov; 124(Pt 21):3537-44. PubMed ID: 22083140
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wnt proteins prevent apoptosis of both uncommitted osteoblast progenitors and differentiated osteoblasts by beta-catenin-dependent and -independent signaling cascades involving Src/ERK and phosphatidylinositol 3-kinase/AKT.
    Almeida M; Han L; Bellido T; Manolagas SC; Kousteni S
    J Biol Chem; 2005 Dec; 280(50):41342-51. PubMed ID: 16251184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4-1BB signaling activates the t cell factor 1 effector/β-catenin pathway with delayed kinetics via ERK signaling and delayed PI3K/AKT activation to promote the proliferation of CD8+ T Cells.
    Lee DY; Choi BK; Lee DG; Kim YH; Kim CH; Lee SJ; Kwon BS
    PLoS One; 2013; 8(7):e69677. PubMed ID: 23874982
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.
    Chen M; Philipp M; Wang J; Premont RT; Garrison TR; Caron MG; Lefkowitz RJ; Chen W
    J Biol Chem; 2009 Dec; 284(50):35040-8. PubMed ID: 19801552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.
    Cselenyi CS; Jernigan KK; Tahinci E; Thorne CA; Lee LA; Lee E
    Proc Natl Acad Sci U S A; 2008 Jun; 105(23):8032-7. PubMed ID: 18509060
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway.
    Lu W; Lin C; Roberts MJ; Waud WR; Piazza GA; Li Y
    PLoS One; 2011; 6(12):e29290. PubMed ID: 22195040
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies.
    Kim SE; Huang H; Zhao M; Zhang X; Zhang A; Semonov MV; MacDonald BT; Zhang X; Garcia Abreu J; Peng L; He X
    Science; 2013 May; 340(6134):867-70. PubMed ID: 23579495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Salinomycin suppresses LRP6 expression and inhibits both Wnt/β-catenin and mTORC1 signaling in breast and prostate cancer cells.
    Lu W; Li Y
    J Cell Biochem; 2014 Oct; 115(10):1799-807. PubMed ID: 24905570
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5).
    Palsgaard J; Emanuelli B; Winnay JN; Sumara G; Karsenty G; Kahn CR
    J Biol Chem; 2012 Apr; 287(15):12016-26. PubMed ID: 22337886
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dysregulation of Wnt/β-catenin signaling by protein kinases in hepatocellular carcinoma and its therapeutic application.
    Li Q; Sun M; Wang M; Feng M; Yang F; Li L; Zhao J; Chang C; Dong H; Xie T; Chen J
    Cancer Sci; 2021 May; 112(5):1695-1706. PubMed ID: 33605517
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gbetagamma activates GSK3 to promote LRP6-mediated beta-catenin transcriptional activity.
    Jernigan KK; Cselenyi CS; Thorne CA; Hanson AJ; Tahinci E; Hajicek N; Oldham WM; Lee LA; Hamm HE; Hepler JR; Kozasa T; Linder ME; Lee E
    Sci Signal; 2010 May; 3(121):ra37. PubMed ID: 20460648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.