These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 22559792)

  • 1. ADMET evaluation in drug discovery. 11. PharmacoKinetics Knowledge Base (PKKB): a comprehensive database of pharmacokinetic and toxic properties for drugs.
    Cao D; Wang J; Zhou R; Li Y; Yu H; Hou T
    J Chem Inf Model; 2012 May; 52(5):1132-7. PubMed ID: 22559792
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Current development of integrated web servers for preclinical safety and pharmacokinetics assessments in drug development.
    Hsiao Y; Su BH; Tseng YJ
    Brief Bioinform; 2021 May; 22(3):. PubMed ID: 32770190
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modeling of drug absorption, distribution, metabolism, excretion, and toxicity.
    Gaohua L; Miao X; Dou L
    Expert Opin Drug Metab Toxicol; 2021 Sep; 17(9):1103-1124. PubMed ID: 34253134
    [No Abstract]   [Full Text] [Related]  

  • 4. In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.
    Sjögren E; Westergren J; Grant I; Hanisch G; Lindfors L; Lennernäs H; Abrahamsson B; Tannergren C
    Eur J Pharm Sci; 2013 Jul; 49(4):679-98. PubMed ID: 23727464
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PK/DB: database for pharmacokinetic properties and predictive in silico ADME models.
    Moda TL; Torres LG; Carrara AE; Andricopulo AD
    Bioinformatics; 2008 Oct; 24(19):2270-1. PubMed ID: 18684738
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IDAAPM: integrated database of ADMET and adverse effects of predictive modeling based on FDA approved drug data.
    Legehar A; Xhaard H; Ghemtio L
    J Cheminform; 2016; 8():33. PubMed ID: 27303447
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties.
    Xiong G; Wu Z; Yi J; Fu L; Yang Z; Hsieh C; Yin M; Zeng X; Wu C; Lu A; Chen X; Hou T; Cao D
    Nucleic Acids Res; 2021 Jul; 49(W1):W5-W14. PubMed ID: 33893803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interpretable-ADMET: a web service for ADMET prediction and optimization based on deep neural representation.
    Wei Y; Li S; Li Z; Wan Z; Lin J
    Bioinformatics; 2022 May; 38(10):2863-2871. PubMed ID: 35561160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modeling ADMET.
    Ghosh J; Lawless MS; Waldman M; Gombar V; Fraczkiewicz R
    Methods Mol Biol; 2016; 1425():63-83. PubMed ID: 27311462
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADMET modeling approaches in drug discovery.
    Ferreira LLG; Andricopulo AD
    Drug Discov Today; 2019 May; 24(5):1157-1165. PubMed ID: 30890362
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Predictive QSAR modeling for the successful predictions of the ADMET properties of candidate drug molecules.
    Khan MT; Sylte I
    Curr Drug Discov Technol; 2007 Oct; 4(3):141-9. PubMed ID: 17985997
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADMETopt: A Web Server for ADMET Optimization in Drug Design via Scaffold Hopping.
    Yang H; Sun L; Wang Z; Li W; Liu G; Tang Y
    J Chem Inf Model; 2018 Oct; 58(10):2051-2056. PubMed ID: 30251842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relating molecular properties and in vitro assay results to in vivo drug disposition and toxicity outcomes.
    Sutherland JJ; Raymond JW; Stevens JL; Baker TK; Watson DE
    J Med Chem; 2012 Jul; 55(14):6455-66. PubMed ID: 22716080
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery.
    Lin J; Sahakian DC; de Morais SM; Xu JJ; Polzer RJ; Winter SM
    Curr Top Med Chem; 2003; 3(10):1125-54. PubMed ID: 12769713
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor.
    Zhang L; Mao Y; Gao Z; Chen X; Li X; Liu Y; Xia G
    Eur J Drug Metab Pharmacokinet; 2020 Feb; 45(1):15-26. PubMed ID: 31494843
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recent uses of topological indices in the development of in silico ADMET models.
    Votano JR
    Curr Opin Drug Discov Devel; 2005 Jan; 8(1):32-7. PubMed ID: 15679169
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PharmaBench: Enhancing ADMET benchmarks with large language models.
    Niu Z; Xiao X; Wu W; Cai Q; Jiang Y; Jin W; Wang M; Yang G; Kong L; Jin X; Yang G; Chen H
    Sci Data; 2024 Sep; 11(1):985. PubMed ID: 39256394
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of ADMET Predictor in Early Discovery Drug Metabolism and Pharmacokinetics Project Work.
    Sohlenius-Sternbeck AK; Terelius Y
    Drug Metab Dispos; 2022 Feb; 50(2):95-104. PubMed ID: 34750195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures.
    Pires DE; Blundell TL; Ascher DB
    J Med Chem; 2015 May; 58(9):4066-72. PubMed ID: 25860834
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles.
    Sanders JM; Beshore DC; Culberson JC; Fells JI; Imbriglio JE; Gunaydin H; Haidle AM; Labroli M; Mattioni BE; Sciammetta N; Shipe WD; Sheridan RP; Suen LM; Verras A; Walji A; Joshi EM; Bueters T
    J Med Chem; 2017 Aug; 60(16):6771-6780. PubMed ID: 28418656
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.