260 related articles for article (PubMed ID: 22560300)
21. GPR119 agonists: a promising approach for T2DM treatment? A SWOT analysis of GPR119.
Kang SU
Drug Discov Today; 2013 Dec; 18(23-24):1309-15. PubMed ID: 24060477
[TBL] [Abstract][Full Text] [Related]
22. Modulating GPR40: therapeutic promise and potential in diabetes.
Poitout V; Lin DC
Drug Discov Today; 2013 Dec; 18(23-24):1301-8. PubMed ID: 24051395
[TBL] [Abstract][Full Text] [Related]
23. Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents.
Overton HA; Babbs AJ; Doel SM; Fyfe MC; Gardner LS; Griffin G; Jackson HC; Procter MJ; Rasamison CM; Tang-Christensen M; Widdowson PS; Williams GM; Reynet C
Cell Metab; 2006 Mar; 3(3):167-75. PubMed ID: 16517404
[TBL] [Abstract][Full Text] [Related]
24. Activation of GPR119 by fatty acid agonists augments insulin release from clonal β-cells and isolated pancreatic islets and improves glucose tolerance in mice.
Moran BM; Abdel-Wahab YH; Flatt PR; McKillop AM
Biol Chem; 2014 Apr; 395(4):453-64. PubMed ID: 24323890
[TBL] [Abstract][Full Text] [Related]
25. 5-Hydroxy-eicosapentaenoic acid is an endogenous GPR119 agonist and enhances glucose-dependent insulin secretion.
Kogure R; Toyama K; Hiyamuta S; Kojima I; Takeda S
Biochem Biophys Res Commun; 2011 Dec; 416(1-2):58-63. PubMed ID: 22079287
[TBL] [Abstract][Full Text] [Related]
26. GPR119 agonists for the treatment of type 2 diabetes: an updated patent review (2014-present).
Li H; Fang Y; Guo S; Yang Z
Expert Opin Ther Pat; 2021 Sep; 31(9):795-808. PubMed ID: 33896337
[No Abstract] [Full Text] [Related]
27. Angelica dahurica Extracts Improve Glucose Tolerance through the Activation of GPR119.
Park EY; Kim EH; Kim CY; Kim MH; Choung JS; Oh YS; Moon HS; Jun HS
PLoS One; 2016; 11(7):e0158796. PubMed ID: 27391814
[TBL] [Abstract][Full Text] [Related]
28. GPR119 agonists 2009-2011.
Buzard DJ; Lehmann J; Han S; Jones RM
Pharm Pat Anal; 2012 Jul; 1(3):285-99. PubMed ID: 24236842
[TBL] [Abstract][Full Text] [Related]
29. Therapeutic application of GPR119 ligands in metabolic disorders.
Yang JW; Kim HS; Choi YW; Kim YM; Kang KW
Diabetes Obes Metab; 2018 Feb; 20(2):257-269. PubMed ID: 28722242
[TBL] [Abstract][Full Text] [Related]
30. Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series.
Han S; Narayanan S; Kim SH; Calderon I; Zhu X; Kawasaki A; Yue D; Lehmann J; Wong A; Buzard DJ; Semple G; Carroll C; Chu ZL; Al-Sharmma H; Shu HH; Tung SF; Unett DJ; Behan DP; Yoon WH; Morgan M; Usmani KA; Chen C; Sadeque A; Leonard JN; Jones RM
Bioorg Med Chem Lett; 2015 Aug; 25(15):3034-8. PubMed ID: 26048791
[TBL] [Abstract][Full Text] [Related]
31. High-throughput screening for GPR119 modulators identifies a novel compound with anti-diabetic efficacy in db/db mice.
Zhang M; Feng Y; Wang J; Zhao J; Li T; He M; Yang D; Nosjean O; Boutin J; Renard P; Wang MW
PLoS One; 2013; 8(5):e63861. PubMed ID: 23704946
[TBL] [Abstract][Full Text] [Related]
32. 2-OMe-lysophosphatidylcholine analogues are GPR119 ligands and activate insulin secretion from βTC-3 pancreatic cells: Evaluation of structure-dependent biological activity.
Drzazga A; Sowińska A; Krzemińska A; Okruszek A; Paneth P; Koziołkiewicz M; Gendaszewska-Darmach E
Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Jan; 1863(1):91-103. PubMed ID: 29079451
[TBL] [Abstract][Full Text] [Related]
33. The cytoprotective effects of oleoylethanolamide in insulin-secreting cells do not require activation of GPR119.
Stone VM; Dhayal S; Smith DM; Lenaghan C; Brocklehurst KJ; Morgan NG
Br J Pharmacol; 2012 Apr; 165(8):2758-70. PubMed ID: 22029844
[TBL] [Abstract][Full Text] [Related]
34. Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells.
Ning Y; O'Neill K; Lan H; Pang L; Shan LX; Hawes BE; Hedrick JA
Br J Pharmacol; 2008 Dec; 155(7):1056-65. PubMed ID: 18724386
[TBL] [Abstract][Full Text] [Related]
35. The significance of GPR119 agonists as a future treatment for type 2 diabetes.
Dhayal S; Morgan NG
Drug News Perspect; 2010 Sep; 23(7):418-24. PubMed ID: 20862393
[TBL] [Abstract][Full Text] [Related]
36. Fatty acid binding receptors and their physiological role in type 2 diabetes.
Swaminath G
Arch Pharm (Weinheim); 2008 Dec; 341(12):753-61. PubMed ID: 19009545
[TBL] [Abstract][Full Text] [Related]
37. Discovery, optimisation and in vivo evaluation of novel GPR119 agonists.
Brocklehurst KJ; Broo A; Butlin RJ; Brown HS; Clarke DS; Davidsson Ö; Goldberg K; Groombridge SD; Kelly EE; Leach A; McKerrecher D; O'Donnell C; Poucher S; Schofield P; Scott JS; Teague J; Westgate L; Wood MJ
Bioorg Med Chem Lett; 2011 Dec; 21(24):7310-6. PubMed ID: 22061639
[TBL] [Abstract][Full Text] [Related]
38. N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119.
Chu ZL; Carroll C; Chen R; Alfonso J; Gutierrez V; He H; Lucman A; Xing C; Sebring K; Zhou J; Wagner B; Unett D; Jones RM; Behan DP; Leonard J
Mol Endocrinol; 2010 Jan; 24(1):161-70. PubMed ID: 19901198
[TBL] [Abstract][Full Text] [Related]
39. GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space.
Chen C; Li H; Long YQ
Bioorg Med Chem Lett; 2016 Dec; 26(23):5603-5612. PubMed ID: 27825762
[TBL] [Abstract][Full Text] [Related]
40. Is GPR119 agonism an appropriate treatment modality for the safe amelioration of metabolic diseases?
Cornall LM; Mathai ML; Hryciw DH; McAinch AJ
Expert Opin Investig Drugs; 2013 Apr; 22(4):487-98. PubMed ID: 23442069
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]