These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 22561024)

  • 1. Implication of MEK1 and MEK2 in the establishment of the blood-placenta barrier during placentogenesis in mouse.
    Charron J; Bissonauth V; Nadeau V
    Reprod Biomed Online; 2012 Jul; 25(1):58-67. PubMed ID: 22561024
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Mek1 and Mek2 functions in the formation of the blood placental barrier].
    Nadeau V; Bissonauth V; Charron J
    Med Sci (Paris); 2012 Apr; 28(4):409-15. PubMed ID: 22549869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Essential role of the ERK/MAPK pathway in blood-placental barrier formation.
    Nadeau V; Charron J
    Development; 2014 Jul; 141(14):2825-37. PubMed ID: 24948605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.
    Aoidi R; Maltais A; Charron J
    Sci Signal; 2016 Jan; 9(412):ra9. PubMed ID: 26814233
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation.
    Nadeau V; Guillemette S; Bélanger LF; Jacob O; Roy S; Charron J
    Development; 2009 Apr; 136(8):1363-74. PubMed ID: 19304888
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta.
    Giroux S; Tremblay M; Bernard D; Cardin-Girard JF; Aubry S; Larouche L; Rousseau S; Huot J; Landry J; Jeannotte L; Charron J
    Curr Biol; 1999 Apr; 9(7):369-72. PubMed ID: 10209122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crucial requirement of ERK/MAPK signaling in respiratory tract development.
    Boucherat O; Nadeau V; Bérubé-Simard FA; Charron J; Jeannotte L
    Development; 2014 Aug; 141(16):3197-211. PubMed ID: 25100655
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal.
    Catalanotti F; Reyes G; Jesenberger V; Galabova-Kovacs G; de Matos Simoes R; Carugo O; Baccarini M
    Nat Struct Mol Biol; 2009 Mar; 16(3):294-303. PubMed ID: 19219045
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road.
    Caunt CJ; Sale MJ; Smith PD; Cook SJ
    Nat Rev Cancer; 2015 Oct; 15(10):577-92. PubMed ID: 26399658
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis.
    Bissonauth V; Roy S; Gravel M; Guillemette S; Charron J
    Development; 2006 Sep; 133(17):3429-40. PubMed ID: 16887817
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia.
    Scholl FA; Dumesic PA; Barragan DI; Harada K; Bissonauth V; Charron J; Khavari PA
    Dev Cell; 2007 Apr; 12(4):615-29. PubMed ID: 17419998
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition.
    Ohren JF; Chen H; Pavlovsky A; Whitehead C; Zhang E; Kuffa P; Yan C; McConnell P; Spessard C; Banotai C; Mueller WT; Delaney A; Omer C; Sebolt-Leopold J; Dudley DT; Leung IK; Flamme C; Warmus J; Kaufman M; Barrett S; Tecle H; Hasemann CA
    Nat Struct Mol Biol; 2004 Dec; 11(12):1192-7. PubMed ID: 15543157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
    Gailhouste L; Ezan F; Bessard A; Frémin C; Rageul J; Langouët S; Baffet G
    Int J Cancer; 2010 Mar; 126(6):1367-77. PubMed ID: 19816936
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MEK1 and MEK2 differentially control the duration and amplitude of the ERK cascade response.
    Kocieniewski P; Lipniacki T
    Phys Biol; 2013 Jun; 10(3):035006. PubMed ID: 23735655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.
    Bardwell AJ; Abdollahi M; Bardwell L
    Biochem J; 2003 Mar; 370(Pt 3):1077-85. PubMed ID: 12529172
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aberrant extracellular signal-regulated kinase (ERK)1/2 signalling in suicide brain: role of ERK kinase 1 (MEK1).
    Dwivedi Y; Rizavi HS; Zhang H; Roberts RC; Conley RR; Pandey GN
    Int J Neuropsychopharmacol; 2009 Nov; 12(10):1337-54. PubMed ID: 19835659
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.
    Voisin L; Julien C; Duhamel S; Gopalbhai K; Claveau I; Saba-El-Leil MK; Rodrigue-Gervais IG; Gaboury L; Lamarre D; Basik M; Meloche S
    BMC Cancer; 2008 Nov; 8():337. PubMed ID: 19014680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IQGAP1 is a scaffold for mitogen-activated protein kinase signaling.
    Roy M; Li Z; Sacks DB
    Mol Cell Biol; 2005 Sep; 25(18):7940-52. PubMed ID: 16135787
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of ERK/MAPK in the lateral amygdala of the mouse is required for acquisition of a fear-potentiated startle response.
    Di Benedetto B; Kallnik M; Weisenhorn DM; Falls WA; Wurst W; Hölter SM
    Neuropsychopharmacology; 2009 Jan; 34(2):356-66. PubMed ID: 18432190
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential expression of MEK1 and MEK2 during mouse development.
    Alessandrini A; Brott BK; Erikson RL
    Cell Growth Differ; 1997 May; 8(5):505-11. PubMed ID: 9149902
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.