353 related articles for article (PubMed ID: 22561515)
1. Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1.
Jaeger E; Leedham S; Lewis A; Segditsas S; Becker M; Cuadrado PR; Davis H; Kaur K; Heinimann K; Howarth K; ; East J; Taylor J; Thomas H; Tomlinson I
Nat Genet; 2012 May; 44(6):699-703. PubMed ID: 22561515
[TBL] [Abstract][Full Text] [Related]
2. Clinicopathological features of a kindred with SCG5-GREM1-associated hereditary mixed polyposis syndrome.
Plesec T; Brown K; Allen C; A Burke C; Church J; Kalady M; LaGuardia L; O'Malley M; Heald B
Hum Pathol; 2017 Feb; 60():75-81. PubMed ID: 27984123
[TBL] [Abstract][Full Text] [Related]
3. Identification of a novel GREM1 duplication in a patient with multiple colon polyps.
McKenna DB; Van Den Akker J; Zhou AY; Ryan L; Leon A; O'Connor R; Shah PD; Rustgi AK; Katona BW
Fam Cancer; 2019 Jan; 18(1):63-66. PubMed ID: 29804199
[TBL] [Abstract][Full Text] [Related]
4. Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.
Clendenning M; Young JP; Walsh MD; Woodall S; Arnold J; Jenkins M; Win AK; Hopper JL; Sweet K; Gallinger S; Rosty C; Parry S; Buchanan DD
PLoS One; 2013; 8(6):e66705. PubMed ID: 23805267
[TBL] [Abstract][Full Text] [Related]
5. Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.
Davis H; Irshad S; Bansal M; Rafferty H; Boitsova T; Bardella C; Jaeger E; Lewis A; Freeman-Mills L; Giner FC; Rodenas-Cuadrado P; Mallappa S; Clark S; Thomas H; Jeffery R; Poulsom R; Rodriguez-Justo M; Novelli M; Chetty R; Silver A; Sansom OJ; Greten FR; Wang LM; East JE; Tomlinson I; Leedham SJ
Nat Med; 2015 Jan; 21(1):62-70. PubMed ID: 25419707
[TBL] [Abstract][Full Text] [Related]
6. Genomic rearrangements of the GREM1-FMN1 locus cause oligosyndactyly, radio-ulnar synostosis, hearing loss, renal defects syndrome and Cenani--Lenz-like non-syndromic oligosyndactyly.
Dimitrov BI; Voet T; De Smet L; Vermeesch JR; Devriendt K; Fryns JP; Debeer P
J Med Genet; 2010 Aug; 47(8):569-74. PubMed ID: 20610440
[TBL] [Abstract][Full Text] [Related]
7. GREM1 and POLE variants in hereditary colorectal cancer syndromes.
Rohlin A; Eiengård F; Lundstam U; Zagoras T; Nilsson S; Edsjö A; Pedersen J; Svensson J; Skullman S; Karlsson BG; Björk J; Nordling M
Genes Chromosomes Cancer; 2016 Jan; 55(1):95-106. PubMed ID: 26493165
[TBL] [Abstract][Full Text] [Related]
8. Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: counselling and management recommendations.
Ziai J; Matloff E; Choi J; Kombo N; Materin M; Bale AE
Genet Res (Camb); 2016 Mar; 98():e5. PubMed ID: 26947005
[TBL] [Abstract][Full Text] [Related]
9. Features of Patients With Hereditary Mixed Polyposis Syndrome Caused by Duplication of GREM1 and Implications for Screening and Surveillance.
Lieberman S; Walsh T; Schechter M; Adar T; Goldin E; Beeri R; Sharon N; Baris H; Ben Avi L; Half E; Lerer I; Shirts BH; Pritchard CC; Tomlinson I; King MC; Levy-Lahad E; Peretz T; Goldberg Y
Gastroenterology; 2017 Jun; 152(8):1876-1880.e1. PubMed ID: 28242209
[TBL] [Abstract][Full Text] [Related]
10. GREM1 germline mutation screening in Ashkenazi Jewish patients with familial colorectal cancer.
Laitman Y; Jaeger E; Katz L; Tomlinson I; Friedman E
Genet Res (Camb); 2015 May; 97():e11. PubMed ID: 25992589
[TBL] [Abstract][Full Text] [Related]
11. Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds.
Li D; Yuan D; Shen H; Mao X; Yuan S; Liu Q
Mol Vis; 2019; 25():625-635. PubMed ID: 31700227
[TBL] [Abstract][Full Text] [Related]
12. A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.
Lewis A; Freeman-Mills L; de la Calle-Mustienes E; Giráldez-Pérez RM; Davis H; Jaeger E; Becker M; Hubner NC; Nguyen LN; Zeron-Medina J; Bond G; Stunnenberg HG; Carvajal JJ; Gomez-Skarmeta JL; Leedham S; Tomlinson I
Cell Rep; 2014 Aug; 8(4):983-90. PubMed ID: 25131200
[TBL] [Abstract][Full Text] [Related]
13. Prognostic significance of stromal GREM1 expression in colorectal cancer.
Jang BG; Kim HS; Chang WY; Bae JM; Oh HJ; Wen X; Jeong S; Cho NY; Kim WH; Kang GH
Hum Pathol; 2017 Apr; 62():56-65. PubMed ID: 28041973
[TBL] [Abstract][Full Text] [Related]
14. Meta-analysis of the rs4779584 polymorphism and colorectal cancer risk.
Yang H; Gao Y; Feng T; Jin TB; Kang LL; Chen C
PLoS One; 2014; 9(2):e89736. PubMed ID: 24586997
[TBL] [Abstract][Full Text] [Related]
15. Cenani-Lenz syndrome and other related syndactyly disorders due to variants in LRP4, GREM1/FMN1, and APC: Insight into the pathogenesis and the relationship to polyposis through the WNT and BMP antagonistic pathways.
Al-Qattan MM; Alkuraya FS
Am J Med Genet A; 2019 Feb; 179(2):266-279. PubMed ID: 30569497
[TBL] [Abstract][Full Text] [Related]
16. Mapping of hereditary mixed polyposis syndrome (HMPS) to chromosome 10q23 by genomewide high-density single nucleotide polymorphism (SNP) scan and identification of BMPR1A loss of function.
Cao X; Eu KW; Kumarasinghe MP; Li HH; Loi C; Cheah PY
J Med Genet; 2006 Mar; 43(3):e13. PubMed ID: 16525031
[TBL] [Abstract][Full Text] [Related]
17. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression.
Ren J; Smid M; Iaria J; Salvatori DCF; van Dam H; Zhu HJ; Martens JWM; Ten Dijke P
Breast Cancer Res; 2019 Sep; 21(1):109. PubMed ID: 31533776
[TBL] [Abstract][Full Text] [Related]
18. Genetic mapping of hereditary mixed polyposis syndrome to chromosome 6q.
Thomas HJ; Whitelaw SC; Cottrell SE; Murday VA; Tomlinson IP; Markie D; Jones T; Bishop DT; Hodgson SV; Sheer D; Northover JM; Talbot IC; Solomon E; Bodmer WF
Am J Hum Genet; 1996 Apr; 58(4):770-6. PubMed ID: 8644741
[TBL] [Abstract][Full Text] [Related]
19. BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2.
Bayne RA; Donnachie DJ; Kinnell HL; Childs AJ; Anderson RA
Mol Hum Reprod; 2016 Sep; 22(9):622-33. PubMed ID: 27385727
[TBL] [Abstract][Full Text] [Related]
20. Germline bone morphogenesis protein receptor 1A mutation causes colorectal tumorigenesis in hereditary mixed polyposis syndrome.
Cheah PY; Wong YH; Chau YP; Loi C; Lim KH; Lim JF; Koh PK; Eu KW
Am J Gastroenterol; 2009 Dec; 104(12):3027-33. PubMed ID: 19773747
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]