188 related articles for article (PubMed ID: 22570068)
21. Rescue of amyotrophic lateral sclerosis phenotype in a mouse model by intravenous AAV9-ADAR2 delivery to motor neurons.
Yamashita T; Chai HL; Teramoto S; Tsuji S; Shimazaki K; Muramatsu S; Kwak S
EMBO Mol Med; 2013 Nov; 5(11):1710-9. PubMed ID: 24115583
[TBL] [Abstract][Full Text] [Related]
22. RNA editing of the Q/R site of GluA2 in different cultured cell lines that constitutively express different levels of RNA editing enzyme ADAR2.
Yamashita T; Tadami C; Nishimoto Y; Hideyama T; Kimura D; Suzuki T; Kwak S
Neurosci Res; 2012 May; 73(1):42-8. PubMed ID: 22366356
[TBL] [Abstract][Full Text] [Related]
23. Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2.
Hideyama T; Yamashita T; Suzuki T; Tsuji S; Higuchi M; Seeburg PH; Takahashi R; Misawa H; Kwak S
J Neurosci; 2010 Sep; 30(36):11917-25. PubMed ID: 20826656
[TBL] [Abstract][Full Text] [Related]
24. MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.
MacNair L; Xiao S; Miletic D; Ghani M; Julien JP; Keith J; Zinman L; Rogaeva E; Robertson J
Brain; 2016 Jan; 139(Pt 1):86-100. PubMed ID: 26525917
[TBL] [Abstract][Full Text] [Related]
25. Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).
Volkening K; Leystra-Lantz C; Yang W; Jaffee H; Strong MJ
Brain Res; 2009 Dec; 1305():168-82. PubMed ID: 19815002
[TBL] [Abstract][Full Text] [Related]
26. Phosphorylated TDP-43 becomes resistant to cleavage by calpain: A regulatory role for phosphorylation in TDP-43 pathology of ALS/FTLD.
Yamashita T; Teramoto S; Kwak S
Neurosci Res; 2016 Jun; 107():63-9. PubMed ID: 26723245
[TBL] [Abstract][Full Text] [Related]
27. RNA Editing: A New Therapeutic Target in Amyotrophic Lateral Sclerosis and Other Neurological Diseases.
Hosaka T; Tsuji H; Kwak S
Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681616
[TBL] [Abstract][Full Text] [Related]
28. Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA.
Kawahara Y; Sun H; Ito K; Hideyama T; Aoki M; Sobue G; Tsuji S; Kwak S
Neurosci Res; 2006 Jan; 54(1):11-4. PubMed ID: 16225946
[TBL] [Abstract][Full Text] [Related]
29. [The implications of TDP-43 mutations in pathogenesis of amyotrophic lateral sclerosis].
Ishihara T; Yokoseki A; Nishizawa M; Takahashi H; Onodera O
Brain Nerve; 2009 Nov; 61(11):1301-7. PubMed ID: 19938687
[TBL] [Abstract][Full Text] [Related]
30. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
Ishihara T; Ariizumi Y; Shiga A; Kato T; Tan CF; Sato T; Miki Y; Yokoo M; Fujino T; Koyama A; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
Hum Mol Genet; 2013 Oct; 22(20):4136-47. PubMed ID: 23740936
[TBL] [Abstract][Full Text] [Related]
31. A system-wide mislocalization of RNA-binding proteins in motor neurons is a new feature of ALS.
Liu YJ; Kuo HC; Chern Y
Neurobiol Dis; 2021 Dec; 160():105531. PubMed ID: 34634461
[TBL] [Abstract][Full Text] [Related]
32. A role for calpain-dependent cleavage of TDP-43 in amyotrophic lateral sclerosis pathology.
Yamashita T; Hideyama T; Hachiga K; Teramoto S; Takano J; Iwata N; Saido TC; Kwak S
Nat Commun; 2012; 3():1307. PubMed ID: 23250437
[TBL] [Abstract][Full Text] [Related]
33. [ALS and excitatory amino acid].
Aizawa H; Kwak S
Brain Nerve; 2007 Oct; 59(10):1117-27. PubMed ID: 17969352
[TBL] [Abstract][Full Text] [Related]
34. Pathological and immunoblot analysis of phosphorylated TDP-43 in sporadic amyotrophic lateral sclerosis with pallido-nigro-luysian degeneration.
Uchino A; Ogino M; Takahashi-Fujigasaki J; Oonuma S; Kanazawa N; Kajita S; Ichinoe M; Hasegawa M; Nishiyama K; Murayama S
Neuropathology; 2018 Apr; 38(2):171-178. PubMed ID: 28906030
[TBL] [Abstract][Full Text] [Related]
35. Testing of the therapeutic efficacy and safety of AMPA receptor RNA aptamers in an ALS mouse model.
Akamatsu M; Yamashita T; Teramoto S; Huang Z; Lynch J; Toda T; Niu L; Kwak S
Life Sci Alliance; 2022 Apr; 5(4):. PubMed ID: 35022247
[TBL] [Abstract][Full Text] [Related]
36. Loss of nuclear TDP-43 in amyotrophic lateral sclerosis (ALS) causes altered expression of splicing machinery and widespread dysregulation of RNA splicing in motor neurones.
Highley JR; Kirby J; Jansweijer JA; Webb PS; Hewamadduma CA; Heath PR; Higginbottom A; Raman R; Ferraiuolo L; Cooper-Knock J; McDermott CJ; Wharton SB; Shaw PJ; Ince PG
Neuropathol Appl Neurobiol; 2014 Oct; 40(6):670-85. PubMed ID: 24750229
[TBL] [Abstract][Full Text] [Related]
37. [Perampanel for Sporadic Amyotrophic Lateral Sclerosis].
Aizawa H; Kwak S
Brain Nerve; 2019 Nov; 71(11):1270-1278. PubMed ID: 31722313
[TBL] [Abstract][Full Text] [Related]
38. Newly identified ADAR-mediated A-to-I editing positions as a tool for ALS research.
Kwak S; Nishimoto Y; Yamashita T
RNA Biol; 2008; 5(4):193-7. PubMed ID: 18971634
[TBL] [Abstract][Full Text] [Related]
39. Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
Sawada J; Yamashita T; Aizawa H; Aburakawa Y; Hasebe N; Kwak S
Neurosci Res; 2009 Jul; 64(3):251-8. PubMed ID: 19447293
[TBL] [Abstract][Full Text] [Related]
40. Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress.
Onda-Ohto A; Hasegawa-Ogawa M; Matsuno H; Shiraishi T; Bono K; Hiraki H; Kanegae Y; Iguchi Y; Okano HJ
Mol Brain; 2023 Jul; 16(1):62. PubMed ID: 37496071
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
