These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 22570300)

  • 1. Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.
    Liu F; Park JE; Qian WJ; Lim D; Scharow A; Berg T; Yaffe MB; Lee KS; Burke TR
    Chembiochem; 2012 Jun; 13(9):1291-6. PubMed ID: 22570300
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of high affinity polo-like kinase 1 (Plk1) polo-box domain binding peptides using oxime-based diversification.
    Liu F; Park JE; Qian WJ; Lim D; Scharow A; Berg T; Yaffe MB; Lee KS; Burke TR
    ACS Chem Biol; 2012 May; 7(5):805-10. PubMed ID: 22292814
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-proteinogenic amino acids in the pThr-2 position of a pentamer peptide that confer high binding affinity for the polo box domain (PBD) of polo-like kinase 1 (Plk1).
    Qian WJ; Park JE; Lee KS; Burke TR
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7306-8. PubMed ID: 23159568
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A new class of peptidomimetics targeting the polo-box domain of Polo-like kinase 1.
    Ahn M; Han YH; Park JE; Kim S; Lee WC; Lee SJ; Gunasekaran P; Cheong C; Shin SY; Kim HY; Ryu EK; Murugan RN; Kim NH; Bang JK
    J Med Chem; 2015 Jan; 58(1):294-304. PubMed ID: 25347203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Exploring the binding nature of pyrrolidine pocket-dependent interactions in the polo-box domain of polo-like kinase 1.
    Murugan RN; Ahn M; Lee WC; Kim HY; Song JH; Cheong C; Hwang E; Seo JH; Shin SY; Choi SH; Park JE; Bang JK
    PLoS One; 2013; 8(11):e80043. PubMed ID: 24223211
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymoquinone blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic.
    Yin Z; Song Y; Rehse PH
    ACS Chem Biol; 2013 Feb; 8(2):303-8. PubMed ID: 23135290
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural analysis of the polo-box domain of human Polo-like kinase 2.
    Kim JH; Ku B; Lee KS; Kim SJ
    Proteins; 2015 Jul; 83(7):1201-8. PubMed ID: 25846005
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Application of oxime-diversification to optimize ligand interactions within a cryptic pocket of the polo-like kinase 1 polo-box domain.
    Zhao XZ; Hymel D; Burke TR
    Bioorg Med Chem Lett; 2016 Oct; 26(20):5009-5012. PubMed ID: 27624074
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
    Yun SM; Moulaei T; Lim D; Bang JK; Park JE; Shenoy SR; Liu F; Kang YH; Liao C; Soung NK; Lee S; Yoon DY; Lim Y; Lee DH; Otaka A; Appella E; McMahon JB; Nicklaus MC; Burke TR; Yaffe MB; Wlodawer A; Lee KS
    Nat Struct Mol Biol; 2009 Aug; 16(8):876-82. PubMed ID: 19597481
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of a nuclear localization signal in the polo box domain of Plk1.
    Lee MS; Huang YH; Huang SP; Lin RI; Wu SF; Li C
    Biochim Biophys Acta; 2009 Oct; 1793(10):1571-8. PubMed ID: 19631697
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular and enzoinformatics perspectives of targeting Polo-like kinase 1 in cancer therapy.
    Shakil S; Baig MH; Tabrez S; Rizvi SMD; Zaidi SK; Ashraf GM; Ansari SA; Khan AAP; Al-Qahtani MH; Abuzenadah AM; Chaudhary AG
    Semin Cancer Biol; 2019 Jun; 56():47-55. PubMed ID: 29122685
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects on polo-like kinase 1 polo-box domain binding affinities of peptides incurred by structural variation at the phosphoamino acid position.
    Qian W; Park JE; Liu F; Lee KS; Burke TR
    Bioorg Med Chem; 2013 Jul; 21(14):3996-4003. PubMed ID: 22743087
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high Plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in HeLa cells.
    Qian WJ; Park JE; Lim D; Lai CC; Kelley JA; Park SY; Lee KW; Yaffe MB; Lee KS; Burke TR
    Biopolymers; 2014 Nov; 102(6):444-55. PubMed ID: 25283071
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pinning down the polo-box domain.
    Lee KS; Idle JR
    Chem Biol; 2008 May; 15(5):415-6. PubMed ID: 18482691
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhancing polo-like kinase 1 selectivity of polo-box domain-binding peptides.
    Zhao XZ; Hymel D; Burke TR
    Bioorg Med Chem; 2017 Oct; 25(19):5041-5049. PubMed ID: 28285924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of mammalian polo-like kinase 1 (Plk1) localization: self- versus non-self-priming.
    Lee KS; Park JE; Kang YH; Zimmerman W; Soung NK; Seong YS; Kwak SJ; Erikson RL
    Cell Cycle; 2008 Jan; 7(2):141-5. PubMed ID: 18216497
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Polo-box domain: a versatile mediator of polo-like kinase function.
    Park JE; Soung NK; Johmura Y; Kang YH; Liao C; Lee KH; Park CH; Nicklaus MC; Lee KS
    Cell Mol Life Sci; 2010 Jun; 67(12):1957-70. PubMed ID: 20148280
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphatase-Stable Phosphoamino Acid Mimetics That Enhance Binding Affinities with the Polo-Box Domain of Polo-like Kinase 1.
    Hymel D; Burke TR
    ChemMedChem; 2017 Feb; 12(3):202-206. PubMed ID: 27992122
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural insights into the inhibitor binding and new inhibitor design to Polo-like kinase-1 Polo-box domain using computational studies.
    Abdullah M; Guruprasad L
    J Biomol Struct Dyn; 2019 Aug; 37(13):3410-3421. PubMed ID: 30146942
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.
    Murugan RN; Park JE; Lim D; Ahn M; Cheong C; Kwon T; Nam KY; Choi SH; Kim BY; Yoon DY; Yaffe MB; Yu DY; Lee KS; Bang JK
    Bioorg Med Chem; 2013 May; 21(9):2623-34. PubMed ID: 23498919
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.