161 related articles for article (PubMed ID: 22570686)
1. Overexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cells.
Bier C; Hecht R; Kunst L; Scheiding S; Wünsch D; Goesswein D; Schneider G; Krämer OH; Knauer SK; Stauber RH
PLoS One; 2012; 7(5):e34142. PubMed ID: 22570686
[TBL] [Abstract][Full Text] [Related]
2. Allosteric inhibition of Taspase1's pathobiological activity by enforced dimerization in vivo.
Bier C; Knauer SK; Wünsch D; Kunst L; Scheiding S; Kaiser M; Ottmann C; Krämer OH; Stauber RH
FASEB J; 2012 Aug; 26(8):3421-9. PubMed ID: 22623586
[TBL] [Abstract][Full Text] [Related]
3. Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein.
Sabiani S; Geppert T; Engelbrecht C; Kowarz E; Schneider G; Marschalek R
EBioMedicine; 2015 May; 2(5):386-95. PubMed ID: 26137584
[TBL] [Abstract][Full Text] [Related]
4. The heterodimerization domains of MLL-FYRN and FYRC--are potential target structures in t(4;11) leukemia.
Pless B; Oehm C; Knauer S; Stauber RH; Dingermann T; Marschalek R
Leukemia; 2011 Apr; 25(4):663-70. PubMed ID: 21233834
[TBL] [Abstract][Full Text] [Related]
5. The importin-alpha/nucleophosmin switch controls taspase1 protease function.
Bier C; Knauer SK; Docter D; Schneider G; Krämer OH; Stauber RH
Traffic; 2011 Jun; 12(6):703-14. PubMed ID: 21418451
[TBL] [Abstract][Full Text] [Related]
6. Bioassays to monitor Taspase1 function for the identification of pharmacogenetic inhibitors.
Knauer SK; Fetz V; Rabenstein J; Friedl S; Hofmann B; Sabiani S; Schröder E; Kunst L; Proschak E; Thines E; Kindler T; Schneider G; Marschalek R; Stauber RH; Bier C
PLoS One; 2011; 6(5):e18253. PubMed ID: 21647428
[TBL] [Abstract][Full Text] [Related]
7. Cryptic splice site activation during RNA processing of MLL/AF4 chimeric transcripts in infants with t(4;11) positive ALL.
Divoky V; Trka JM; Watzinger F; Lion T
Gene; 2000 Apr; 247(1-2):111-8. PubMed ID: 10773450
[TBL] [Abstract][Full Text] [Related]
8. Clinical significance of MLL-AF4 fusion transcript expression in the absence of a cytogenetically detectable t(4;11)(q21;q23) chromosomal translocation.
Uckun FM; Herman-Hatten K; Crotty ML; Sensel MG; Sather HN; Tuel-Ahlgren L; Sarquis MB; Bostrom B; Nachman JB; Steinherz PG; Gaynon PS; Heerema N
Blood; 1998 Aug; 92(3):810-21. PubMed ID: 9680349
[TBL] [Abstract][Full Text] [Related]
9. Leukemic fusion genes MLL/AF4 and AML1/MTG8 support leukemic self-renewal by controlling expression of the telomerase subunit TERT.
Gessner A; Thomas M; Castro PG; Büchler L; Scholz A; Brümmendorf TH; Soria NM; Vormoor J; Greil J; Heidenreich O
Leukemia; 2010 Oct; 24(10):1751-9. PubMed ID: 20686504
[TBL] [Abstract][Full Text] [Related]
10. A Novel t(4;11)(q21;q23) MLL-AF4 fusion transcript in infant leukemia.
Abdelhaleem M; Yi Q; Beimnet K; Grant R
Am J Hematol; 2007 Mar; 82(3):247. PubMed ID: 16924642
[No Abstract] [Full Text] [Related]
11. A novel infant acute lymphoblastic leukemia cell line with MLL-AF5q31 fusion transcript.
Imamura T; Morimoto A; Ikushima S; Kakazu N; Hada S; Tabata Y; Yagi T; Inaba T; Hibi S; Sugimoto T; Imashuku S
Leukemia; 2002 Nov; 16(11):2302-8. PubMed ID: 12399976
[TBL] [Abstract][Full Text] [Related]
12. Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Salvatore F; Esposito G
Cell Oncol (Dordr); 2019 Dec; 42(6):829-845. PubMed ID: 31493143
[TBL] [Abstract][Full Text] [Related]
13. LAF4, an AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia.
von Bergh AR; Beverloo HB; Rombout P; van Wering ER; van Weel MH; Beverstock GC; Kluin PM; Slater RM; Schuuring E
Genes Chromosomes Cancer; 2002 Sep; 35(1):92-6. PubMed ID: 12203795
[TBL] [Abstract][Full Text] [Related]
14. Taspase1: a 'misunderstood' protease with translational cancer relevance.
Wünsch D; Hahlbrock A; Jung S; Schirmeister T; van den Boom J; Schilling O; Knauer SK; Stauber RH
Oncogene; 2016 Jun; 35(26):3351-64. PubMed ID: 26657154
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure of human Taspase1, a crucial protease regulating the function of MLL.
Khan JA; Dunn BM; Tong L
Structure; 2005 Oct; 13(10):1443-52. PubMed ID: 16216576
[TBL] [Abstract][Full Text] [Related]
16. Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants.
Driessen EM; van Roon EH; Spijkers-Hagelstein JA; Schneider P; de Lorenzo P; Valsecchi MG; Pieters R; Stam RW
Haematologica; 2013 Jun; 98(6):937-44. PubMed ID: 23403319
[TBL] [Abstract][Full Text] [Related]
17. Pro-B-cell to pre-B-cell development in B-lineage acute lymphoblastic leukemia expressing the MLL/AF4 fusion protein.
Bertrand FE; Vogtenhuber C; Shah N; LeBien TW
Blood; 2001 Dec; 98(12):3398-405. PubMed ID: 11719380
[TBL] [Abstract][Full Text] [Related]
18. Cryptic t(4;11) encoding MLL-AF4 due to insertion of 5' MLL sequences in chromosome 4.
von Bergh A; Gargallo P; De Prijck B; Vranckx H; Marschalek R; Larripa I; Kluin P; Schuuring E; Hagemeijer A
Leukemia; 2001 Apr; 15(4):595-600. PubMed ID: 11368362
[TBL] [Abstract][Full Text] [Related]
19. RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction.
Wilkinson AC; Ballabio E; Geng H; North P; Tapia M; Kerry J; Biswas D; Roeder RG; Allis CD; Melnick A; de Bruijn MF; Milne TA
Cell Rep; 2013 Jan; 3(1):116-27. PubMed ID: 23352661
[TBL] [Abstract][Full Text] [Related]
20. Disease-relevant signalling-pathways in head and neck cancer: Taspase1's proteolytic activity fine-tunes TFIIA function.
Gribko A; Hahlbrock A; Strieth S; Becker S; Hagemann J; Deichelbohrer M; Hildebrandt A; Habtemichael N; Wünsch D
Sci Rep; 2017 Nov; 7(1):14937. PubMed ID: 29097782
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]