BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 22575566)

  • 1. Mutant human myocilin induces strain specific differences in ocular hypertension and optic nerve damage in mice.
    McDowell CM; Luan T; Zhang Z; Putliwala T; Wordinger RJ; Millar JC; John SW; Pang IH; Clark AF
    Exp Eye Res; 2012 Jul; 100():65-72. PubMed ID: 22575566
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutated myocilin and heterozygous Sod2 deficiency act synergistically in a mouse model of open-angle glaucoma.
    Joe MK; Nakaya N; Abu-Asab M; Tomarev SI
    Hum Mol Genet; 2015 Jun; 24(12):3322-34. PubMed ID: 25740847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma.
    Zode GS; Bugge KE; Mohan K; Grozdanic SD; Peters JC; Koehn DR; Anderson MG; Kardon RH; Stone EM; Sheffield VC
    Invest Ophthalmol Vis Sci; 2012 Mar; 53(3):1557-65. PubMed ID: 22328638
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma.
    Zode GS; Kuehn MH; Nishimura DY; Searby CC; Mohan K; Grozdanic SD; Bugge K; Anderson MG; Clark AF; Stone EM; Sheffield VC
    J Clin Invest; 2011 Sep; 121(9):3542-53. PubMed ID: 21821918
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork.
    Kasetti RB; Phan TN; Millar JC; Zode GS
    Invest Ophthalmol Vis Sci; 2016 Nov; 57(14):6058-6069. PubMed ID: 27820874
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intraocular pressure across the lifespan of Tg-MYOC
    Zhang X; Xi G; Feng P; Li C; Kuehn MH; Zhu W
    Exp Eye Res; 2024 Apr; 241():109855. PubMed ID: 38453040
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma.
    Zhou Y; Grinchuk O; Tomarev SI
    Invest Ophthalmol Vis Sci; 2008 May; 49(5):1932-9. PubMed ID: 18436825
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glaucomatous MYOC mutations activate the IL-1/NF-κB inflammatory stress response and the glaucoma marker SELE in trabecular meshwork cells.
    Itakura T; Peters DM; Fini ME
    Mol Vis; 2015; 21():1071-84. PubMed ID: 26396484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tissue Transglutaminase Elevates Intraocular Pressure in Mice.
    Raychaudhuri U; Millar JC; Clark AF
    Invest Ophthalmol Vis Sci; 2017 Dec; 58(14):6197-6211. PubMed ID: 29222550
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
    Patil SV; Kaipa BR; Ranshing S; Sundaresan Y; Millar JC; Nagarajan B; Kiehlbauch C; Zhang Q; Jain A; Searby CC; Scheetz TE; Clark AF; Sheffield VC; Zode GS
    Sci Rep; 2024 Mar; 14(1):6958. PubMed ID: 38521856
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of the myocilin (MYOC) glaucoma gene in monkey and human steroid-induced ocular hypertension.
    Fingert JH; Clark AF; Craig JE; Alward WL; Snibson GR; McLaughlin M; Tuttle L; Mackey DA; Sheffield VC; Stone EM
    Invest Ophthalmol Vis Sci; 2001 Jan; 42(1):145-52. PubMed ID: 11133859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetically increasing Myoc expression supports a necessary pathologic role of abnormal proteins in glaucoma.
    Gould DB; Miceli-Libby L; Savinova OV; Torrado M; Tomarev SI; Smith RS; John SW
    Mol Cell Biol; 2004 Oct; 24(20):9019-25. PubMed ID: 15456875
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Adenoviral gene transfer of active human transforming growth factor-{beta}2 elevates intraocular pressure and reduces outflow facility in rodent eyes.
    Shepard AR; Millar JC; Pang IH; Jacobson N; Wang WH; Clark AF
    Invest Ophthalmol Vis Sci; 2010 Apr; 51(4):2067-76. PubMed ID: 19959644
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The clinical feature of myocilin Y437H mutation in a Chinese family with primary open-angle glaucoma.
    Lei L; Li S; Liu X; Zhang C
    Br J Ophthalmol; 2019 Oct; 103(10):1524-1529. PubMed ID: 30612094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cross-talk between MYOC p. Y437H mutation and TGF-β2 in the pathology of glaucoma.
    Yang Y; Abdulatef ASWA; Zhang L; Jiang H; Zeng Z; Li H; Xia X
    Int J Med Sci; 2020; 17(8):1062-1070. PubMed ID: 32410836
    [No Abstract]   [Full Text] [Related]  

  • 16. Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye.
    van der Heide CJ; Alward WLM; Flamme-Wiese M; Riker M; Syed NA; Anderson MG; Carter K; Kuehn MH; Stone EM; Mullins RF; Fingert JH
    Ophthalmol Glaucoma; 2018; 1(2):132-138. PubMed ID: 30906929
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutant myocilin nonsecretion in vivo is not sufficient to cause glaucoma.
    Gould DB; Reedy M; Wilson LA; Smith RS; Johnson RL; John SW
    Mol Cell Biol; 2006 Nov; 26(22):8427-36. PubMed ID: 16954374
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gln368STOP myocilin mutation in families with late-onset primary open-angle glaucoma.
    Allingham RR; Wiggs JL; De La Paz MA; Vollrath D; Tallett DA; Broomer B; Jones KH; Del Bono EA; Kern J; Patterson K; Haines JL; Pericak-Vance MA
    Invest Ophthalmol Vis Sci; 1998 Nov; 39(12):2288-95. PubMed ID: 9804137
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle.
    Lynch JM; Dolman AJ; Guo C; Dolan K; Xiang C; Reda S; Li B; Prasanna G
    PLoS One; 2018; 13(11):e0206801. PubMed ID: 30395621
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The application of lentiviral vectors for the establishment of TGFβ2-induced ocular hypertension in C57BL/6J mice.
    Peng M; Margetts TJ; Rayana NP; Sugali CK; Dai J; Mao W
    Exp Eye Res; 2022 Aug; 221():109137. PubMed ID: 35691374
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.