BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

478 related articles for article (PubMed ID: 22575700)

  • 1. Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1.
    Balmus G; Zhu M; Mukherjee S; Lyndaker AM; Hume KR; Lee J; Riccio ML; Reeves AP; Sutter NB; Noden DM; Peters RM; Weiss RS
    Hum Mol Genet; 2012 Aug; 21(15):3408-20. PubMed ID: 22575700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HUS1 regulates in vivo responses to genotoxic chemotherapies.
    Balmus G; Lim PX; Oswald A; Hume KR; Cassano A; Pierre J; Hill A; Huang W; August A; Stokol T; Southard T; Weiss RS
    Oncogene; 2016 Feb; 35(5):662-9. PubMed ID: 25915840
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
    Liu S; Opiyo SO; Manthey K; Glanzer JG; Ashley AK; Amerin C; Troksa K; Shrivastav M; Nickoloff JA; Oakley GG
    Nucleic Acids Res; 2012 Nov; 40(21):10780-94. PubMed ID: 22977173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATM regulates ATR chromatin loading in response to DNA double-strand breaks.
    Cuadrado M; Martinez-Pastor B; Murga M; Toledo LI; Gutierrez-Martinez P; Lopez E; Fernandez-Capetillo O
    J Exp Med; 2006 Feb; 203(2):297-303. PubMed ID: 16461339
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint.
    Lee AY; Chiba T; Truong LN; Cheng AN; Do J; Cho MJ; Chen L; Wu X
    J Biol Chem; 2012 Jan; 287(4):2531-43. PubMed ID: 22123827
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A positive role for c-Abl in Atm and Atr activation in DNA damage response.
    Wang X; Zeng L; Wang J; Chau JF; Lai KP; Jia D; Poonepalli A; Hande MP; Liu H; He G; He L; Li B
    Cell Death Differ; 2011 Jan; 18(1):5-15. PubMed ID: 20798688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular basis of ataxia telangiectasia and related diseases.
    Ball LG; Xiao W
    Acta Pharmacol Sin; 2005 Aug; 26(8):897-907. PubMed ID: 16038621
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATM and the molecular pathogenesis of ataxia telangiectasia.
    McKinnon PJ
    Annu Rev Pathol; 2012; 7():303-21. PubMed ID: 22035194
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATR and H2AX cooperate in maintaining genome stability under replication stress.
    Chanoux RA; Yin B; Urtishak KA; Asare A; Bassing CH; Brown EJ
    J Biol Chem; 2009 Feb; 284(9):5994-6003. PubMed ID: 19049966
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
    Martínez P; Flores JM; Blasco MA
    J Cell Biol; 2012 Apr; 197(2):283-300. PubMed ID: 22508511
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.
    Difilippantonio S; Celeste A; Fernandez-Capetillo O; Chen HT; Reina San Martin B; Van Laethem F; Yang YP; Petukhova GV; Eckhaus M; Feigenbaum L; Manova K; Kruhlak M; Camerini-Otero RD; Sharan S; Nussenzweig M; Nussenzweig A
    Nat Cell Biol; 2005 Jul; 7(7):675-85. PubMed ID: 15965469
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Function of the ATR N-terminal domain revealed by an ATM/ATR chimera.
    Chen X; Zhao R; Glick GG; Cortez D
    Exp Cell Res; 2007 May; 313(8):1667-74. PubMed ID: 17376433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophosphorylation and ATM activation: additional sites add to the complexity.
    Kozlov SV; Graham ME; Jakob B; Tobias F; Kijas AW; Tanuji M; Chen P; Robinson PJ; Taucher-Scholz G; Suzuki K; So S; Chen D; Lavin MF
    J Biol Chem; 2011 Mar; 286(11):9107-19. PubMed ID: 21149446
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia.
    Rimkus SA; Katzenberger RJ; Trinh AT; Dodson GE; Tibbetts RS; Wassarman DA
    Genes Dev; 2008 May; 22(9):1205-20. PubMed ID: 18408079
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.
    Tomimatsu N; Mukherjee B; Burma S
    EMBO Rep; 2009 Jun; 10(6):629-35. PubMed ID: 19444312
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.
    Smith J; Tho LM; Xu N; Gillespie DA
    Adv Cancer Res; 2010; 108():73-112. PubMed ID: 21034966
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.
    Yamauchi M; Oka Y; Yamamoto M; Niimura K; Uchida M; Kodama S; Watanabe M; Sekine I; Yamashita S; Suzuki K
    DNA Repair (Amst); 2008 Mar; 7(3):405-17. PubMed ID: 18248856
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA replication stress-induced phosphorylation of cyclic AMP response element-binding protein mediated by ATM.
    Dodson GE; Tibbetts RS
    J Biol Chem; 2006 Jan; 281(3):1692-7. PubMed ID: 16293623
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ataxia-telangiectasia and related diseases.
    Frappart PO; McKinnon PJ
    Neuromolecular Med; 2006; 8(4):495-511. PubMed ID: 17028372
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.