BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 22576130)

  • 21. Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.
    Toulany M; Lee KJ; Fattah KR; Lin YF; Fehrenbacher B; Schaller M; Chen BP; Chen DJ; Rodemann HP
    Mol Cancer Res; 2012 Jul; 10(7):945-57. PubMed ID: 22596249
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Irinotecan and DNA-PKcs inhibitors synergize in killing of colon cancer cells.
    Davidson D; Coulombe Y; Martinez-Marignac VL; Amrein L; Grenier J; Hodkinson K; Masson JY; Aloyz R; Panasci L
    Invest New Drugs; 2012 Jun; 30(3):1248-56. PubMed ID: 21221710
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
    Calabrese CR; Almassy R; Barton S; Batey MA; Calvert AH; Canan-Koch S; Durkacz BW; Hostomsky Z; Kumpf RA; Kyle S; Li J; Maegley K; Newell DR; Notarianni E; Stratford IJ; Skalitzky D; Thomas HD; Wang LZ; Webber SE; Williams KJ; Curtin NJ
    J Natl Cancer Inst; 2004 Jan; 96(1):56-67. PubMed ID: 14709739
    [TBL] [Abstract][Full Text] [Related]  

  • 24. An Intrinsically Disordered APLF Links Ku, DNA-PKcs, and XRCC4-DNA Ligase IV in an Extended Flexible Non-homologous End Joining Complex.
    Hammel M; Yu Y; Radhakrishnan SK; Chokshi C; Tsai MS; Matsumoto Y; Kuzdovich M; Remesh SG; Fang S; Tomkinson AE; Lees-Miller SP; Tainer JA
    J Biol Chem; 2016 Dec; 291(53):26987-27006. PubMed ID: 27875301
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination.
    Tavecchio M; Munck JM; Cano C; Newell DR; Curtin NJ
    Cancer Chemother Pharmacol; 2012 Jan; 69(1):155-64. PubMed ID: 21630086
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Ku-DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks.
    Mendoza-Munoz PL; Gavande NS; VanderVere-Carozza PS; Pawelczak KS; Dynlacht JR; Garrett JE; Turchi JJ
    NAR Cancer; 2023 Mar; 5(1):zcad003. PubMed ID: 36755959
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Pharmacologic Inhibitor of DNA-PK, M3814, Potentiates Radiotherapy and Regresses Human Tumors in Mouse Models.
    Zenke FT; Zimmermann A; Sirrenberg C; Dahmen H; Kirkin V; Pehl U; Grombacher T; Wilm C; Fuchss T; Amendt C; Vassilev LT; Blaukat A
    Mol Cancer Ther; 2020 May; 19(5):1091-1101. PubMed ID: 32220971
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Targeting the phosphatidylinositol 3-kinase/Akt pathway for enhancing breast cancer cells to radiotherapy.
    Liang K; Jin W; Knuefermann C; Schmidt M; Mills GB; Ang KK; Milas L; Fan Z
    Mol Cancer Ther; 2003 Apr; 2(4):353-60. PubMed ID: 12700279
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair.
    Wang Q; Gao F; Wang T; Flagg T; Deng X
    Neoplasia; 2009 Oct; 11(10):1012-21. PubMed ID: 19794960
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Feedback autophagy activation as a key resistance factor of Ku-0060648 in colorectal cancer cells.
    Mao M; Liu Y; Gao X
    Biochem Biophys Res Commun; 2017 Sep; 490(4):1244-1249. PubMed ID: 28676397
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.
    Li Y; Wang X; Yue P; Tao H; Ramalingam SS; Owonikoko TK; Deng X; Wang Y; Fu H; Khuri FR; Sun SY
    J Biol Chem; 2013 May; 288(19):13215-24. PubMed ID: 23536185
    [TBL] [Abstract][Full Text] [Related]  

  • 32. DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining.
    Head PE; Kapoor-Vazirani P; Nagaraju GP; Zhang H; Rath SK; Luong NC; Haji-Seyed-Javadi R; Sesay F; Wang SY; Duong DM; Daddacha W; Minten EV; Song B; Danelia D; Liu X; Li S; Ortlund EA; Seyfried NT; Smalley DM; Wang Y; Deng X; Dynan WS; El-Rayes B; Davis AJ; Yu DS
    Nucleic Acids Res; 2023 Aug; 51(15):7972-7987. PubMed ID: 37395399
    [TBL] [Abstract][Full Text] [Related]  

  • 33. DNA-PK-dependent phosphorylation of Ku70/80 is not required for non-homologous end joining.
    Douglas P; Gupta S; Morrice N; Meek K; Lees-Miller SP
    DNA Repair (Amst); 2005 Aug; 4(9):1006-18. PubMed ID: 15941674
    [TBL] [Abstract][Full Text] [Related]  

  • 34. DNA-PK inhibition causes a low level of H2AX phosphorylation and homologous recombination repair in Medaka (Oryzias latipes) cells.
    Urushihara Y; Kobayashi J; Matsumoto Y; Komatsu K; Oda S; Mitani H
    Biochem Biophys Res Commun; 2012 Dec; 429(3-4):131-6. PubMed ID: 23142596
    [TBL] [Abstract][Full Text] [Related]  

  • 35. DNA double-strand breaks repair inhibitors potentiates the combined effect of VP-16 and CDDP in human colorectal adenocarcinoma (LoVo) cells.
    Kopa P; Macieja A; Pastwa E; Majsterek I; Poplawski T
    Mol Biol Rep; 2021 Jan; 48(1):709-720. PubMed ID: 33389482
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mechanisms of DNA double strand break repair and chromosome aberration formation.
    Iliakis G; Wang H; Perrault AR; Boecker W; Rosidi B; Windhofer F; Wu W; Guan J; Terzoudi G; Pantelias G
    Cytogenet Genome Res; 2004; 104(1-4):14-20. PubMed ID: 15162010
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The role of insulin-like growth factor binding protein-3 in the breast cancer cell response to DNA-damaging agents.
    Lin MZ; Marzec KA; Martin JL; Baxter RC
    Oncogene; 2014 Jan; 33(1):85-96. PubMed ID: 23178489
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Potentiation of chemosensitivity in multidrug-resistant human leukemia CEM cells by inhibition of DNA-dependent protein kinase using wortmannin.
    Kim SH; Um JH; Dong-Won B; Kwon BH; Kim DW; Chung BS; Kang CD
    Leuk Res; 2000 Nov; 24(11):917-25. PubMed ID: 11086175
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Competitive and noncompetitive inhibition of the DNA-dependent protein kinase.
    Izzard RA; Jackson SP; Smith GC
    Cancer Res; 1999 Jun; 59(11):2581-6. PubMed ID: 10363977
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Autophosphorylation of DNA-PKCS regulates its dynamics at DNA double-strand breaks.
    Uematsu N; Weterings E; Yano K; Morotomi-Yano K; Jakob B; Taucher-Scholz G; Mari PO; van Gent DC; Chen BP; Chen DJ
    J Cell Biol; 2007 Apr; 177(2):219-29. PubMed ID: 17438073
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.