BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

103 related articles for article (PubMed ID: 22576206)

  • 1. Cancer cell metabolism: there is no ROS for the weary.
    Dang CV
    Cancer Discov; 2012 Apr; 2(4):304-7. PubMed ID: 22576206
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.
    Ros S; Santos CR; Moco S; Baenke F; Kelly G; Howell M; Zamboni N; Schulze A
    Cancer Discov; 2012 Apr; 2(4):328-43. PubMed ID: 22576210
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer.
    Yi M; Ban Y; Tan Y; Xiong W; Li G; Xiang B
    Mol Metab; 2019 Feb; 20():1-13. PubMed ID: 30553771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.
    Ros S; Flöter J; Kaymak I; Da Costa C; Houddane A; Dubuis S; Griffiths B; Mitter R; Walz S; Blake S; Behrens A; Brindle KM; Zamboni N; Rider MH; Schulze A
    Oncogene; 2017 Jun; 36(23):3287-3299. PubMed ID: 28092678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening.
    Strohecker AM; Joshi S; Possemato R; Abraham RT; Sabatini DM; White E
    Oncogene; 2015 Nov; 34(45):5662-76. PubMed ID: 25772235
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia induces transcription of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 gene via hypoxia-inducible factor-1alpha activation.
    Minchenko O; Opentanova I; Minchenko D; Ogura T; Esumi H
    FEBS Lett; 2004 Oct; 576(1-2):14-20. PubMed ID: 15474002
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fructose-2,6-bisphosphate synthesis by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is required for the glycolytic response to hypoxia and tumor growth.
    Chesney J; Clark J; Klarer AC; Imbert-Fernandez Y; Lane AN; Telang S
    Oncotarget; 2014 Aug; 5(16):6670-86. PubMed ID: 25115398
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vitamin D controls the capacity of human dendritic cells to induce functional regulatory T cells by regulation of glucose metabolism.
    Vanherwegen AS; Eelen G; Ferreira GB; Ghesquière B; Cook DP; Nikolic T; Roep B; Carmeliet P; Telang S; Mathieu C; Gysemans C
    J Steroid Biochem Mol Biol; 2019 Mar; 187():134-145. PubMed ID: 30481575
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 acts as a protein kinase to regulate glioblastoma progression by activating the AKT/forkhead box O1 pathway.
    Zhao K; Yu C; Luo J; Huang M; Wen Q; Zhao N
    Acta Biochim Pol; 2022 Feb; 69(1):165-172. PubMed ID: 35143148
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.
    Dasgupta S; Rajapakshe K; Zhu B; Nikolai BC; Yi P; Putluri N; Choi JM; Jung SY; Coarfa C; Westbrook TF; Zhang XH; Foulds CE; Tsai SY; Tsai MJ; O'Malley BW
    Nature; 2018 Apr; 556(7700):249-254. PubMed ID: 29615789
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of PFKFB4 induces cell cycle arrest and glucose metabolism inhibition by inactivating MEK/ERK/c-Myc pathway in cervical cancer cells.
    Wu Y; Zhang L; Bao Y; Wan B; Shu D; Luo T; He Z
    J Obstet Gynaecol; 2022 Aug; 42(6):2399-2405. PubMed ID: 35659173
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis.
    Pegoraro C; Figueiredo AL; Maczkowiak F; Pouponnot C; Eychène A; Monsoro-Burq AH
    Nat Commun; 2015 Jan; 6():5953. PubMed ID: 25601028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the sugar metabolism of tumors with a first-in-class 6-phosphofructo-2-kinase (PFKFB4) inhibitor.
    Chesney J; Clark J; Lanceta L; Trent JO; Telang S
    Oncotarget; 2015 Jul; 6(20):18001-11. PubMed ID: 26221874
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma.
    Li W; Cohen A; Sun Y; Squires J; Braas D; Graeber TG; Du L; Li G; Li Z; Xu X; Chen X; Huang J
    Mol Cancer Res; 2016 Apr; 14(4):344-53. PubMed ID: 26832214
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of PFKFB4 induces cell death in mitotically arrested ovarian cancer cells.
    Taylor C; Mannion D; Miranda F; Karaminejadranjbar M; Herrero-Gonzalez S; Hellner K; Zheng Y; Bartholomeusz G; Bast RC; Ahmed AA
    Oncotarget; 2017 Mar; 8(11):17960-17980. PubMed ID: 28152500
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.
    Yalcin A; Telang S; Clem B; Chesney J
    Exp Mol Pathol; 2009 Jun; 86(3):174-9. PubMed ID: 19454274
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53 coordinates DNA repair with nucleotide synthesis by suppressing PFKFB3 expression and promoting the pentose phosphate pathway.
    Franklin DA; He Y; Leslie PL; Tikunov AP; Fenger N; Macdonald JM; Zhang Y
    Sci Rep; 2016 Nov; 6():38067. PubMed ID: 27901115
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Androgen stimulates glycolysis for de novo lipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells.
    Moon JS; Jin WJ; Kwak JH; Kim HJ; Yun MJ; Kim JW; Park SW; Kim KS
    Biochem J; 2011 Jan; 433(1):225-33. PubMed ID: 20958264
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence.
    Dai T; Rosario SR; Katsuta E; Sawant Dessai A; Paterson EJ; Novickis AT; Cortes Gomez E; Zhu B; Liu S; Wang H; Abrams SI; Seshadri M; Bshara W; Dasgupta S
    Cell Rep; 2022 Dec; 41(10):111756. PubMed ID: 36476868
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase and tumor cell glycolysis.
    Chesney J
    Curr Opin Clin Nutr Metab Care; 2006 Sep; 9(5):535-9. PubMed ID: 16912547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.