These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

366 related articles for article (PubMed ID: 22577471)

  • 1. Analyzing effects of naturally occurring missense mutations.
    Zhang Z; Miteva MA; Wang L; Alexov E
    Comput Math Methods Med; 2012; 2012():805827. PubMed ID: 22577471
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Revealing the Effects of Missense Mutations Causing Snyder-Robinson Syndrome on the Stability and Dimerization of Spermine Synthase.
    Peng Y; Norris J; Schwartz C; Alexov E
    Int J Mol Sci; 2016 Jan; 17(1):. PubMed ID: 26761001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico and in vitro investigations of the mutability of disease-causing missense mutation sites in spermine synthase.
    Zhang Z; Norris J; Schwartz C; Alexov E
    PLoS One; 2011; 6(5):e20373. PubMed ID: 21647366
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disease risk of missense mutations using structural inference from predicted function.
    Horst JA; Wang K; Horst OV; Cunningham ML; Samudrala R
    Curr Protein Pept Sci; 2010 Nov; 11(7):573-88. PubMed ID: 20887259
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhancing human spermine synthase activity by engineered mutations.
    Zhang Z; Zheng Y; Petukh M; Pegg A; Ikeguchi Y; Alexov E
    PLoS Comput Biol; 2013; 9(2):e1002924. PubMed ID: 23468611
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Computational analysis of missense mutations causing Snyder-Robinson syndrome.
    Zhang Z; Teng S; Wang L; Schwartz CE; Alexov E
    Hum Mutat; 2010 Sep; 31(9):1043-9. PubMed ID: 20556796
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathogenic missense protein variants affect different functional pathways and proteomic features than healthy population variants.
    Laddach A; Ng JCF; Fraternali F
    PLoS Biol; 2021 Apr; 19(4):e3001207. PubMed ID: 33909605
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach.
    George Priya Doss C; Rajith B; Chakraboty C; Balaji V; Magesh R; Gowthami B; Menon S; Swati M; Trivedi M; Paul J; Vasan R; Das M
    Mol Biosyst; 2014 Mar; 10(3):421-36. PubMed ID: 24336963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Toward classification of BRCA1 missense variants using a biophysical approach.
    Rowling PJ; Cook R; Itzhaki LS
    J Biol Chem; 2010 Jun; 285(26):20080-7. PubMed ID: 20378548
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approach.
    Zhang Z; Martiny V; Lagorce D; Ikeguchi Y; Alexov E; Miteva MA
    PLoS One; 2014; 9(10):e110884. PubMed ID: 25340632
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction Interfaces.
    Engin HB; Kreisberg JF; Carter H
    PLoS One; 2016; 11(4):e0152929. PubMed ID: 27043210
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A rational free energy-based approach to understanding and targeting disease-causing missense mutations.
    Zhang Z; Witham S; Petukh M; Moroy G; Miteva M; Ikeguchi Y; Alexov E
    J Am Med Inform Assoc; 2013; 20(4):643-51. PubMed ID: 23408511
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses.
    Banerjee S; Wu Q; Ying Y; Li Y; Shirota M; Neculai D; Li C
    Oncotarget; 2016 Aug; 7(33):52766-52780. PubMed ID: 27421141
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of novel ARG1 mutations causing hyperargininemia and correlation with arginase I activity in erythrocytes.
    Carvalho DR; Brand GD; Brum JM; Takata RI; Speck-Martins CE; Pratesi R
    Gene; 2012 Nov; 509(1):124-30. PubMed ID: 22959135
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and functional impact of missense mutations in TPMT: An integrated computational approach.
    Fazel-Najafabadi E; Vahdat Ahar E; Fattahpour S; Sedghi M
    Comput Biol Chem; 2015 Dec; 59 Pt A():48-55. PubMed ID: 26410243
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Predicting the Effect of Amino Acid Single-Point Mutations on Protein Stability-Large-Scale Validation of MD-Based Relative Free Energy Calculations.
    Steinbrecher T; Zhu C; Wang L; Abel R; Negron C; Pearlman D; Feyfant E; Duan J; Sherman W
    J Mol Biol; 2017 Apr; 429(7):948-963. PubMed ID: 27964946
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Machine learning algorithms for predicting protein folding rates and stability of mutant proteins: comparison with statistical methods.
    Gromiha MM; Huang LT
    Curr Protein Pept Sci; 2011 Sep; 12(6):490-502. PubMed ID: 21787301
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.
    Studer RA; Dessailly BH; Orengo CA
    Biochem J; 2013 Feb; 449(3):581-94. PubMed ID: 23301657
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PROXiMATE: a database of mutant protein-protein complex thermodynamics and kinetics.
    Jemimah S; Yugandhar K; Michael Gromiha M
    Bioinformatics; 2017 Sep; 33(17):2787-2788. PubMed ID: 28498885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular dynamic simulation to explore the molecular basis of Btk-PH domain interaction with Ins(1,3,4,5)P4.
    Lu D; Jiang J; Liang Z; Sun M; Luo C; Shen B; Hu G
    ScientificWorldJournal; 2013; 2013():580456. PubMed ID: 24307874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.